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Questions and Answers
What is the primary factor that affects the color of fresh urine?
What is the primary factor that affects the color of fresh urine?
What is the typical range of colors for fresh urine?
What is the typical range of colors for fresh urine?
What is the classification of urine based on its clarity?
What is the classification of urine based on its clarity?
What is the term for cloudiness caused by excessive cellular material or protein in the urine?
What is the term for cloudiness caused by excessive cellular material or protein in the urine?
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What is NOT a factor that affects the color of fresh urine?
What is NOT a factor that affects the color of fresh urine?
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Which of the following odors is associated with high urea levels in the urine?
Which of the following odors is associated with high urea levels in the urine?
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What is the typical characteristic of fresh urine?
What is the typical characteristic of fresh urine?
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What is the normal range of urine pH?
What is the normal range of urine pH?
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What is the term for a urine volume of less than 500ml/24hr?
What is the term for a urine volume of less than 500ml/24hr?
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What is the normal range of specific gravity in urine?
What is the normal range of specific gravity in urine?
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What is the term for excess protein in the urine?
What is the term for excess protein in the urine?
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At what blood glucose level will glucose appear in the urine?
At what blood glucose level will glucose appear in the urine?
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What is the term for excess sugar in the urine, often associated with diabetes mellitus?
What is the term for excess sugar in the urine, often associated with diabetes mellitus?
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What is the primary function of the kidneys in the process of urination?
What is the primary function of the kidneys in the process of urination?
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What is the term for the process of eliminating waste products from the body through the urine?
What is the term for the process of eliminating waste products from the body through the urine?
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Which of the following is NOT a component of normal urine?
Which of the following is NOT a component of normal urine?
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What is the purpose of the urine dipstick chemical analysis?
What is the purpose of the urine dipstick chemical analysis?
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What is the term for the examination of urine under a microscope?
What is the term for the examination of urine under a microscope?
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What is the term for the study of the structure and function of cells in the urine?
What is the term for the study of the structure and function of cells in the urine?
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Which of the following is a component of a routine urinalysis?
Which of the following is a component of a routine urinalysis?
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What is the term for the examination of urine for abnormal constituents?
What is the term for the examination of urine for abnormal constituents?
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Which of the following is NOT a type of urine test?
Which of the following is NOT a type of urine test?
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What is the purpose of a urine urinalysis?
What is the purpose of a urine urinalysis?
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In which condition do ketones, such as acetone, typically appear in urine?
In which condition do ketones, such as acetone, typically appear in urine?
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What is the primary purpose of centrifuging the specimen in the microscopic examination?
What is the primary purpose of centrifuging the specimen in the microscopic examination?
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What is the recommended volume of the specimen to be collected in the tube?
What is the recommended volume of the specimen to be collected in the tube?
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What is the primary function of the gloves in the microscopic examination?
What is the primary function of the gloves in the microscopic examination?
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What is the duration of centrifugation recommended for the specimen?
What is the duration of centrifugation recommended for the specimen?
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What is the primary purpose of examining the urine sample under low power?
What is the primary purpose of examining the urine sample under low power?
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What is the normal range of RBCs in urine per high power field?
What is the normal range of RBCs in urine per high power field?
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What does the presence of 2 or more WBCs in high power field indicate?
What does the presence of 2 or more WBCs in high power field indicate?
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What is the characteristic of WBCs in urine?
What is the characteristic of WBCs in urine?
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What is the characteristic of epithelial cells in urine?
What is the characteristic of epithelial cells in urine?
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What type of cast is seen in healthy individuals?
What type of cast is seen in healthy individuals?
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What is the commonest organism seen in urine?
What is the commonest organism seen in urine?
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Which of the following crystals is always abnormal in urine?
Which of the following crystals is always abnormal in urine?
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What is an artifact that can be seen in urine samples?
What is an artifact that can be seen in urine samples?
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What is the purpose of collecting the urine sample in a dry and clean container?
What is the purpose of collecting the urine sample in a dry and clean container?
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Study Notes
Urine Exam (GUE)
- Urine is a sterile, liquid by-product of the body, secreted by the kidneys and excreted through the urethra through a process called urination.
Properties of Normal Urine
- Normal urine is sterile and contains no microorganisms.
- Urine is a mixture of water, chemicals, proteins, and electrolytes such as sodium, potassium, urea, creatinine, etc.
- Urine pH ranges from 4.5 to 8.0 and generally reflects blood pH.
Urinalysis
- Urinalysis or general urine exam includes:
- MACROSCOPIC EXAM (visual observation of urine)
- Urine dipstick chemical analysis
- MICROSCOPIC EXAM (examination under a microscope)
MACROSCOPIC EXAM
- Examines urine color, transparency, odor, and volume.
- Normal urine color: pale yellow to amber.
- Transparency: classified as clear or turbid.
- Odor: aromatic (normal), ammoniac (high urea), or fruity (DM due to presence of ketones).
- Volume: normal (800-2000ml/24hr), oliguria (below 500ml/24hr), anuria (below 100ml/24hr), or increased (above 2000ml/24hr).
Urine Dipstick Chemical Analysis
- pH: ranges from 4.5 to 8.0.
- Specific gravity (sp gr): ranges from 1.002 to 1.035 and measures solute concentration.
- Protein: normal range (less than 150mg/24hr); proteinuria means excess protein in urine.
- Glucose: appears in urine when blood glucose is above 180 mg/dl; glycosuria means excess sugar in urine (diabetes mellitus).
- Ketones: like acetone, not found in normal urine, but appears in diabetic ketoacidosis or starvation.
MICROSCOPIC EXAM
- Examines urine under a microscope to identify:
- RBCs (red blood cells)
- WBCs (white blood cells)
- Epithelial cells
- Casts (solid, cylindrical structures formed by debris in kidney)
- Microorganisms (bacteria, yeast, etc.)
- Crystals (uric acid, calcium oxalate, etc.)
RBCs
- Hematuria: presence of abnormal number of RBCs in urine, seen in cases like trauma, stones, infection, or cancer.
- Normally, 4 RBCs are found in high power field (HPF).
WBCs
- Pyuria: presence of abnormal number of WBCs in urine, indicates infection in the renal system.
- High WBCs in urine sample: abnormal.
- WBCs have lobed nuclei and granular cytoplasm.
Epithelial Cells
- Larger than WBCs, contain round or oval nucleus.
- Found in small numbers in the sample.
- Increased in some medical diseases of the kidney, like nephrotic syndrome.
Casts
- Solid, cylindrical structures formed by debris in the kidney.
- Hyaline casts: seen in healthy individuals.
- RBCs casts, WBCs casts, and cellular casts can also be seen.
Microorganisms
- Bacteria are the most common organism seen and common contaminant.
- Fungus, like Trichomonas vaginalis, can also be seen.
Crystals
- Common crystals seen in healthy persons: uric acid, calcium oxalate, and ammonium magnesium phosphate.
- Certain crystals, like cysteine, tyrosine, and leucine, are always abnormal if detected in urine.
Artifacts in Urine Sample
- Hair, air bubbles, fat droplets, and cloth fibers can be present as artifacts in the urine sample.
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Description
Learn about the properties of normal urine, including its composition and pH levels. Understand the process of urinalysis and its significance in medical diagnosis.