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Questions and Answers
What is the primary function of the urinary system?
What is the primary function of the urinary system?
Which structure is NOT part of the kidney's nephron?
Which structure is NOT part of the kidney's nephron?
What composes the renal corpuscle?
What composes the renal corpuscle?
Which layer of Bowman’s capsule is composed of podocytes?
Which layer of Bowman’s capsule is composed of podocytes?
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Which component of the urinary system stores urine before excretion?
Which component of the urinary system stores urine before excretion?
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What type of connective tissue surrounds the kidney?
What type of connective tissue surrounds the kidney?
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How many nephrons does each kidney typically contain?
How many nephrons does each kidney typically contain?
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What is the primary function of the collecting tubules?
What is the primary function of the collecting tubules?
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What is the outer layer of the kidney called?
What is the outer layer of the kidney called?
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Which hormone is secreted by the kidneys to regulate blood pressure?
Which hormone is secreted by the kidneys to regulate blood pressure?
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What is the primary function of the thick continuous basement membrane in the filtration barrier?
What is the primary function of the thick continuous basement membrane in the filtration barrier?
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Which type of cells are responsible for renin secretion in the juxtaglomerular apparatus?
Which type of cells are responsible for renin secretion in the juxtaglomerular apparatus?
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What is the main function of the proximal convoluted tubule (PCT)?
What is the main function of the proximal convoluted tubule (PCT)?
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Which component of the nephron has a brush border on its epithelial cells?
Which component of the nephron has a brush border on its epithelial cells?
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Which part of the urinary passage is lined with transitional epithelium?
Which part of the urinary passage is lined with transitional epithelium?
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What do macula densa cells primarily function as?
What do macula densa cells primarily function as?
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What type of tissue comprises the muscular layer of the urinary passage?
What type of tissue comprises the muscular layer of the urinary passage?
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Where is the juxtaglomerular apparatus (JGA) located?
Where is the juxtaglomerular apparatus (JGA) located?
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Which ion is predominantly reabsorbed in the distal convoluted tubule (DCT) under the influence of aldosterone?
Which ion is predominantly reabsorbed in the distal convoluted tubule (DCT) under the influence of aldosterone?
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What role do mesangial cells play in the glomerulus?
What role do mesangial cells play in the glomerulus?
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Study Notes
Urinary System Histology
- The urinary system comprises paired kidneys and ureters, a urinary bladder, and a urethra.
- Kidneys are bean-shaped retroperitoneal organs, formed of stroma (capsule, renal interstitium, CT) and parenchyma (outer cortex, inner medulla).
- The nephron is the functional unit, consisting of a renal corpuscle and tubule (proximal, loop of Henle, distal, collecting).
- The renal corpuscle includes a glomerulus (vascular ball, 200 µm diameter) covered by Bowman's capsule (double-walled epithelial cup).
- The filtration membrane separates blood in the glomerular capillaries from the urinary space in Bowman's capsule.
- The filtration membrane has fenestrated endothelial cells, a continuous basement membrane, and filtration slits with diaphragms.
- Mesangial cells are stellate cells supporting glomerular capillaries and having phagocytic function.
- The juxtaglomerular apparatus (JGA) includes cells from the distal tubule (macula densa), afferent arteriolar smooth muscle cells (juxtaglomerular cells), and lacis cells (extraglomerular mesangial cells).
- Macula densa acts as osmoreceptors sensitive to sodium concentration in the distal tubule.
- Juxtaglomerular cells secrete renin to regulate blood pressure.
- Lacis cells function in supporting the JGA.
- Proximal convoluted tubule (PCT) is lined with simple cuboidal epithelium with a brush border (microvilli). Its functions include active reabsorption of glucose and amino acids, and reabsorption of Na+, Cl-, K+, and H2O.
- Distal convoluted tubule (DCT) is lined with cuboidal epithelium without a brush border. It functions include reabsorption of Na+, K+, and water under aldosterone and ADH influences, and excretion of H2O and NH3.
- Urinary passages include calyces, pelvis, ureter, bladder, and urethra.
- Urinary passages have a mucosa with transitional epithelium, a muscular layer (detrusor muscle), and an adventitia (loose connective tissue).
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Description
Test your knowledge on the urinary system with this quiz. It covers the structure and function of the kidneys, nephron components, and various associated processes. Perfect for students studying human anatomy and physiology!