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Questions and Answers
What is the primary function of the nephron in the urinary system?
What is the primary function of the nephron in the urinary system?
- Filtration of blood and formation of urine (correct)
- Production of hormones needed for metabolism
- Regulating respiratory rate and gas exchange
- Absorption of nutrients from the digestive tract
Which component of the glomerulus is essential for the filtration process?
Which component of the glomerulus is essential for the filtration process?
- Podocytes that line Bowman’s capsule (correct)
- Cortical tissue surrounding renal pyramids
- Vascular pole that regulates blood flow
- Renal pelvis that collects urine
Which structure is responsible for the secretion of erythropoietin?
Which structure is responsible for the secretion of erythropoietin?
- Ureter
- Renal medulla
- Renal cortex (correct)
- Urethra
What process occurs when the kidneys reabsorb water and solutes back into the bloodstream?
What process occurs when the kidneys reabsorb water and solutes back into the bloodstream?
Which of the following is a function of the urinary system?
Which of the following is a function of the urinary system?
What role do mesangial cells play in the glomerulus?
What role do mesangial cells play in the glomerulus?
In the nephron, which structure is primarily involved in ion balance and absorption of small molecules?
In the nephron, which structure is primarily involved in ion balance and absorption of small molecules?
Which part of the nephron begins the process of filtration?
Which part of the nephron begins the process of filtration?
What anatomical feature allows for the reabsorption of water in the kidneys?
What anatomical feature allows for the reabsorption of water in the kidneys?
Which of these structures is part of the renal corpuscle?
Which of these structures is part of the renal corpuscle?
What is the primary role of Sertoli cells in the male reproductive system?
What is the primary role of Sertoli cells in the male reproductive system?
During which phase of the menstrual cycle do secondary follicles in the ovary become dominant?
During which phase of the menstrual cycle do secondary follicles in the ovary become dominant?
What characterizes the ovulatory phase of the menstrual cycle?
What characterizes the ovulatory phase of the menstrual cycle?
What happens to the corpus luteum if fertilization does not occur?
What happens to the corpus luteum if fertilization does not occur?
During the menstrual phase, what primary change occurs in the endometrial lining?
During the menstrual phase, what primary change occurs in the endometrial lining?
Which structure is responsible for the production of testosterone in the male reproductive system?
Which structure is responsible for the production of testosterone in the male reproductive system?
What type of epithelium lines the vagina?
What type of epithelium lines the vagina?
What is the purpose of cervical effacement during parturition?
What is the purpose of cervical effacement during parturition?
What is characterized by the presence of rugae in the vaginal mucosa?
What is characterized by the presence of rugae in the vaginal mucosa?
What primarily influences the viscosity of cervical mucus?
What primarily influences the viscosity of cervical mucus?
What is the primary function of the enterocytes found in the intestinal villi?
What is the primary function of the enterocytes found in the intestinal villi?
Which of the following glands produces HCl and intrinsic factor?
Which of the following glands produces HCl and intrinsic factor?
Which of the following statements about the crypts of Lieberkuhn is true?
Which of the following statements about the crypts of Lieberkuhn is true?
What type of cells are Paneth cells, and what is their primary function?
What type of cells are Paneth cells, and what is their primary function?
What characterizes the serosa of the gastrointestinal tract?
What characterizes the serosa of the gastrointestinal tract?
Which cells are primarily responsible for local immune responses within the intestinal epithelium?
Which cells are primarily responsible for local immune responses within the intestinal epithelium?
Which structure in the large intestine aids in the absorption of water and electrolytes?
Which structure in the large intestine aids in the absorption of water and electrolytes?
What type of epithelium lines the gastrointestinal tract from the stomach to the intestine?
What type of epithelium lines the gastrointestinal tract from the stomach to the intestine?
What is the main role of the gallbladder?
What is the main role of the gallbladder?
Which layer of the gastrointestinal wall contains the myenteric plexus of Auerbach?
Which layer of the gastrointestinal wall contains the myenteric plexus of Auerbach?
What is the primary acidity producing cell type in the stomach?
What is the primary acidity producing cell type in the stomach?
The accessory glands associated with the oral cavity include which of the following?
The accessory glands associated with the oral cavity include which of the following?
What is the primary secretion type of the parotid gland?
What is the primary secretion type of the parotid gland?
Flashcards
What is a nephron?
What is a nephron?
The functional unit of the kidney, responsible for filtering blood and producing urine.
What is the renal corpuscle?
What is the renal corpuscle?
The initial part of the nephron, composed of the glomerulus and Bowman's capsule, where filtration occurs.
What is the glomerulus?
What is the glomerulus?
A network of capillaries within the Bowman's capsule, where blood is filtered.
What is Bowman's capsule?
What is Bowman's capsule?
The double-walled sac surrounding the glomerulus, collecting the filtered fluid.
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What are renal tubules?
What are renal tubules?
A long tube that extends from Bowman's capsule, responsible for reabsorbing necessary substances and secreting waste.
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What is glomerular filtration?
What is glomerular filtration?
The process by which water and small solutes from the blood move into the nephron's lumen.
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What is tubular reabsorption?
What is tubular reabsorption?
The process by which useful substances move from the nephron's lumen back into the blood.
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What is tubular secretion?
What is tubular secretion?
The process by which waste products move from the blood into the nephron's lumen.
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What is the glomerular filtration barrier?
What is the glomerular filtration barrier?
A specialized barrier that separates blood in the glomerulus from the Bowman's capsule, controlling what gets filtered.
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What are the components of the glomerular filtration barrier?
What are the components of the glomerular filtration barrier?
The main components of the glomerular filtration barrier are the glomerular capillary endothelium, the basement membrane, and the podocyte's filtration slits.
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Transformation Zone
Transformation Zone
Junction between squamous and mucus-secreting columnar epithelium of the cervix.
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Cervical Effacement
Cervical Effacement
Remodelling and collagen removal of the connective tissue of the cervix prior to childbirth. It softens the cervix and allows the cervical canal to dilate.
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Oogenesis: Initial Stage
Oogenesis: Initial Stage
The initial stage of oogenesis where oogonia differentiate into larger cells called primary oocytes.
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Meiosis I in Oogenesis
Meiosis I in Oogenesis
Production of two haploid daughter cells from a primary oocyte. Happens during the first meiotic division of oogenesis.
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Meiosis II in Oogenesis
Meiosis II in Oogenesis
The completion of meiosis II in oogenesis only occurs upon fertilization.
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Menstrual Phase
Menstrual Phase
The first 5 days of the endometrial cycle marked by shedding of the functional layer of the endometrium, triggered by a decrease in progesterone and estrogen.
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Preovulatory Phase
Preovulatory Phase
The phase of the menstrual cycle where the dominant follicle in the ovary starts to grow. It is triggered by FSH.
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Ovulation
Ovulation
The release of the secondary oocyte from the ovary. It is triggered by LH.
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Postovulatory Phase
Postovulatory Phase
The phase of the menstrual cycle where the corpus luteum is formed after ovulation. It is stimulated by LH and produces progesterone.
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Seminiferous Tubules
Seminiferous Tubules
The highly coiled tubes in the testes responsible for producing sperm cells. They contain the germinal epithelium, Sertoli cells, and Leydig cells.
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Intestinal Villi
Intestinal Villi
Finger-like projections of the mucosa, covered by simple columnar epithelium with enterocytes and goblet cells.
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Microvilli
Microvilli
Microscopic projections on the apical surface of enterocytes, forming a brush-like border for increased absorption.
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Fundic Glands
Fundic Glands
Long, tubular glands found in the stomach, responsible for producing gastric juice.
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Parietal or Oxyntic Cells
Parietal or Oxyntic Cells
Cells found in the fundic glands, producing hydrochloric acid (HCl) and intrinsic factor.
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Intrinsic Factor
Intrinsic Factor
A protein secreted by parietal cells, essential for the absorption of vitamin B12 in the ileum.
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Chief or Zymogenic Cells
Chief or Zymogenic Cells
Cells found in the fundic glands, responsible for producing pepsinogen, a precursor to the digestive enzyme pepsin.
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Mucous Neck Cells
Mucous Neck Cells
Cells found in the gastric pits, responsible for producing mucus, which protects the stomach lining from its acidic environment.
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Paneth Cells
Paneth Cells
Cells found in the base of the crypts of Lieberkühn, secreting lysozyme, phospholipase A2, and defensins, which have antimicrobial properties.
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M-cells (Microfold Cells)
M-cells (Microfold Cells)
Specialized epithelial cells in the ileum, involved in the transport of antigens from the lumen to the underlying lymphoid tissue.
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Crypts of Lieberkühn
Crypts of Lieberkühn
Small, tubular glands found in the small intestine, responsible for secreting digestive enzymes and mucus.
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Peyer's Patches
Peyer's Patches
Aggregates of lymphoid tissue found in the submucosa of the small intestine, particularly in the ileum, which are important for immune responses.
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Vermiform Appendix
Vermiform Appendix
A small, finger-shaped projection extending from the cecum, containing lymphoid tissue, which functions in immune defense.
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Glands of Brunner
Glands of Brunner
Compound coiled tubular glands found in the duodenum, responsible for secreting alkaline mucus that neutralizes chyme entering from the stomach.
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Taenia Coli
Taenia Coli
Longitudinal bands of smooth muscle that run along the length of the large intestine, responsible for its characteristic segmentation.
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Hepatic Lobule
Hepatic Lobule
The functional unit of the liver, composed of hepatocytes arranged in plates around a central vein.
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Urinary System
- Organs: paired kidneys, ureters, urinary bladder, urethra
- Functions: eliminate waste, regulate blood volume, ion concentration, and acid-base balance, regulate red blood cell production, excrete bioactive substances, control blood pressure, converts Vitamin D3 to its active form, and gluconeogenesis during starvation.
Kidneys
- Location: retroperitoneal, superior lumbar region.
- Right kidney lower than left.
- Enveloped by a fibrous capsule.
- Hilus: gateway where renal artery, renal vein, and ureter pass.
- Consists of cortex and medulla.
- Renal cortex outer layer; medulla inner layer containing renal columns, renal papilla, minor calyx, and major calyx.
- Renal papilla: tip of renal pyramids, terminal portions of 25 papillary ducts.
- Renal lobe: renal pyramid and surrounding cortical tissue
- Renal lobule: collecting tubules, papillary ducts, nephrons.
- Renal pelvis: union of major calyces.
- Renal pyramids: conical structures in the medulla.
- Uriniferous tubule: nephron + intrarenal ducts (collecting tubules and papillary ducts).
- Medullary rays: parallel tubes at corticomedullary junction (center of renal lobule).
- Collectives tubules and loops of Henle are located at the collecting tubules' initial segment.
- Interstitial tissue: collagen fibers, capillaries, fibroblasts, mononuclear cells, and interstitial cells.
Nephron
- Structural and functional unit of the kidney.
- Renal corpuscle (malpighian corpuscle): glomerulus and Bowman's capsule.
- Renal tubules: proximal convoluted tubule, loop of Henle, distal tubule, and collecting tubule.
- Vascular pole: afferent and efferent arterioles.
- Urinary pole: Bowman capsule, proximal convoluted tubule.
- Glomerulus: fenestrated glomerular capillaries.
- Mesangial matrix: space between glomerular capillaries.
- Mesangial cells: phagocytic stellate cells, abundant in vascular pole.
- Bowman's capsule: double-walled sac encapsulating the glomerulus.
- Visceral layer (inner): podocytes with cytoplasmic processes.
- Parietal layer (outer): simple squamous epithelium.
- Bowman's space: space between visceral and parietal layers.
Renal Function
- Filtration: water and solutes from blood to nephron lumen.
- Tubular reabsorption: substances from tubular lumen to interstitium and capillaries.
- Tubular secretion: substances from epithelial cells to tubular lumen.
- Glomerular filtration barrier: separates blood from Bowman's capsule. Composed of endothelium, basal lamina, slit membrane, and subpodocyte space.
Basal Lamina
- Layers: Lamina rara externa, Lamina dense, and Lamina rara interna.
- Important for glomerular filtration.
Renal Corpuscle
- Filtrate flows into renal tubules for reabsorption and secretion.
- 20% of blood plasma is filtered.
Proximal Convoluted Tubule
- Reabsorbs 70-80% water, sodium ions, glucose, amino acids, and other substances.
- Secretes creatinine and foreign substances.
Loop of Henle
- Water retention by producing hypertonic urine.
- Thin limb and thick descending limb are in the medulla.
- Thick ascending limb is in the medulla and returns to the cortex.
Distal Convoluted Tubules
- Reabsorbs water and sodium ions under aldosterone influence, (minimal water).
- Secretes potassium and hydrogen ions.
Collecting Tubules
- Collecting tubules carry filtrate to the collecting system, which transports it to a minor calyx.
Other information
- The nephron, loop of Henle, and collecting tubule work together to filter impurities from the blood. This filtrate is modified to concentrate urine, and regulate the amount of water and waste materials excreted.
- The information for the different segments of the kidney demonstrates the interdependency between the different anatomical parts of the renal system.
- The kidney is a vital organ for maintaining homeostasis.
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