Urinary Formation and Composition

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Questions and Answers

What is the treatment of choice for severe hypoglycemia?

  • Normal Saline
  • Sodium Bicarbonate
  • Dextrose 50% in Water (correct)
  • Lactated Ringer's Solution

What is the principle anion of intracellular fluid (ICF)?

  • Phosphorus (correct)
  • Chloride
  • Potassium
  • Sodium

Which of the following conditions is characterized by decreased serum magnesium levels?

  • Hypochloremia
  • Hyperphosphatemia
  • Hypermagnesemia
  • Hypomagnesemia (correct)

What is a potential risk of infusing certain solutions with blood products?

<p>Embolism of RBCs (B)</p> Signup and view all the answers

Which type of intravenous fluids is NOT categorized as isotonic, hypotonic, or hypertonic?

<p>Colloid solution (D)</p> Signup and view all the answers

What type of solution is blood classified as?

<p>Colloid (B)</p> Signup and view all the answers

Which of the following electrolytes is primarily involved in muscle contraction?

<p>Calcium (A)</p> Signup and view all the answers

Through which mechanism are monomers of carbohydrates absorbed into the bloodstream?

<p>Facilitated diffusion (D)</p> Signup and view all the answers

Which fat-soluble vitamins are absorbed along with lipids?

<p>Vitamins A, D, E, and K (A)</p> Signup and view all the answers

What regulates calcium absorption in the body?

<p>PTH (Parathyroid Hormone) (D)</p> Signup and view all the answers

Which site is not mentioned as a common location for IV insertion?

<p>Jugular vein (C)</p> Signup and view all the answers

What is the primary absorption site for water in the digestive system?

<p>Small intestine (B)</p> Signup and view all the answers

Which statement is true about iron absorption in the body?

<p>It depends on the body’s need for iron. (B)</p> Signup and view all the answers

What condition is indicated by increased serum levels of sodium?

<p>Hypernatremia (A)</p> Signup and view all the answers

Which solution is hypotonic once absorbed in the body?

<p>Dextrose 5% in Water (C)</p> Signup and view all the answers

What is the normal range for sodium in mEq/L?

<p>135-145 (C)</p> Signup and view all the answers

What is the primary function of magnesium in the body?

<p>Promoting transmission of neuromuscular activity (A)</p> Signup and view all the answers

Which solution is used for initial fluid and electrolyte replacement in combined water and sodium depletion?

<p>Dextrose 5% in Normal Saline Solution (C)</p> Signup and view all the answers

What is hypercalcemia defined as?

<p>Increased serum calcium levels (B)</p> Signup and view all the answers

Which cation is the major extracellular component?

<p>Sodium (A)</p> Signup and view all the answers

Which electrolyte deficiency is associated with decreased serum potassium levels?

<p>Hypokalemia (D)</p> Signup and view all the answers

What is the primary purpose of absorption in the digestive system?

<p>To absorb nutrients into the blood for utilization (B)</p> Signup and view all the answers

Which function of the digestive system involves the production and release of digestive enzymes?

<p>Secretion (B)</p> Signup and view all the answers

Which organ is not considered part of the gastrointestinal (GI) tract?

<p>Pancreas (A)</p> Signup and view all the answers

What is the role of mixing and propulsion in the digestive system?

<p>To mix ingested food with digestive secretions and move it along (B)</p> Signup and view all the answers

What is the significance of the skin in relation to the digestive system?

<p>It is involved in the production of vitamin D (C)</p> Signup and view all the answers

Which component is primarily involved in the elimination of waste from the digestive system?

<p>Excretion (D)</p> Signup and view all the answers

Which element is essential for the proper functioning of the digestive system, allowing nutrient transport across the body?

<p>Blood (D)</p> Signup and view all the answers

What is the major function of accessory digestive organs like the liver and pancreas?

<p>To aid in digestion through enzyme and secretion production (D)</p> Signup and view all the answers

What type of cells are considered normal in urine but can be reported based on their quantity?

<p>Squamous epithelial cells (D)</p> Signup and view all the answers

What is indicated if crystals like uric acid and cystine are found in urine sediments?

<p>Potential disease states (C)</p> Signup and view all the answers

What is the primary component of urine after passing through the kidneys?

<p>4% dissolved substances (C)</p> Signup and view all the answers

Which of the following substances is not typically found in normal urine?

<p>Fat (A)</p> Signup and view all the answers

What substance is primarily secreted into urine to maintain sodium levels?

<p>Hydrogen (B)</p> Signup and view all the answers

What measurement technique is most commonly used to measure the specific gravity of urine?

<p>Refractometer (B)</p> Signup and view all the answers

What is the primary function of nephron units in the kidneys?

<p>Filtration and reabsorption of blood (A)</p> Signup and view all the answers

What change in urine color may indicate a patient is taking rifampin?

<p>Orange urine (B)</p> Signup and view all the answers

What is the maximum concentration level of glucose in blood before it is reabsorbed?

<p>180 mg/dl (B)</p> Signup and view all the answers

Which type of urine specimen is most concentrated?

<p>First morning specimen (A)</p> Signup and view all the answers

What is the purpose of chemical examination of urine?

<p>To detect abnormal constituents (A)</p> Signup and view all the answers

Why should urine specimens be labeled immediately after collection?

<p>To ensure patient identification (C)</p> Signup and view all the answers

What is the normal volume of urine eliminated daily?

<p>1-2 liters (A)</p> Signup and view all the answers

What could changing urine odor indicate?

<p>Infection or metabolic disorders (A)</p> Signup and view all the answers

What is a precaution to take when handling urine specimens?

<p>Use personal protective equipment (C)</p> Signup and view all the answers

What can cause a variation in urine appearance?

<p>Diet and hydration status (A)</p> Signup and view all the answers

What is the primary function of mechanical digestion?

<p>To use muscular forces to digest nutrients (C)</p> Signup and view all the answers

Which organ is responsible for detoxifying nutrients before they enter general circulation?

<p>Liver (A)</p> Signup and view all the answers

The serous membrane that holds abdominal organs in position is known as what?

<p>Peritoneum (B)</p> Signup and view all the answers

Which phase of gastric secretion starts when the body senses food?

<p>Cephalic phase (B)</p> Signup and view all the answers

How does bile aid in lipid digestion?

<p>It emulsifies lipids to make them easier to digest (C)</p> Signup and view all the answers

Which section of the small intestine is most responsible for the majority of nutrient absorption?

<p>Jejunum (D)</p> Signup and view all the answers

Which type of salivary gland is located beneath the jawbone?

<p>Submandibular gland (D)</p> Signup and view all the answers

What structure connects the stomach to the duodenum and regulates movement into the small intestine?

<p>Pyloric sphincter (A)</p> Signup and view all the answers

What is the role of the brush border enzymes in carbohydrate digestion?

<p>To break down carbohydrates into monosaccharides (B)</p> Signup and view all the answers

Which part of the esophagus contains skeletal muscle?

<p>Upper third (A)</p> Signup and view all the answers

What is the main function of the large intestine?

<p>Complete absorption of nutrients and form feces (D)</p> Signup and view all the answers

What regulates the flow of bile from the gallbladder to the duodenum?

<p>Sphincter of Oddi (D)</p> Signup and view all the answers

What is a common function of the pancreas?

<p>Secrets enzymes for macronutrient digestion (B)</p> Signup and view all the answers

Flashcards

Hypochloremia

A condition where the level of chloride in the extracellular fluid (ECF) is lower than normal.

Hyperchloremia

A condition where the level of chloride in the extracellular fluid (ECF) is higher than normal.

Hypophosphatemia

A condition where the level of phosphorus in the intracellular fluid (ICF) is lower than normal.

Hyperphosphatemia

A condition where the level of phosphorus in the intracellular fluid (ICF) is higher than normal.

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Dextrose 50% in Water

A hypertonic solution used to treat severe hypoglycemia.

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Digestion

The breakdown of ingested food into smaller molecules that the body can absorb.

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Secretion

The production and release of fluids like saliva, gastric juices, and bile, which aid in digestion.

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Mixing and propulsion

The movement of food through the digestive tract, including churning and squeezing actions.

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Absorption

The process of taking nutrients from digested food into the bloodstream.

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Excretion

The elimination of waste products from the digestive system as feces.

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Gastrointestinal (GI) tract

A long, continuous tube that begins with the mouth and ends with the anus, where food passes through.

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Accessory digestive organs

Organs that are not part of the GI tract but help with digestion, including the liver, pancreas, gallbladder, and salivary glands.

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What are the functions of the digestive system?

The functions are: digestion, secretion, mixing and propulsion, absorption, and excretion.

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What is the primary role of the GI tract?

The GI tract is responsible for breaking down and absorbing nutrients from the food we eat.

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Why are the accessory digestive organs important?

They help with digestion by producing enzymes and fluids that break down food and aid in the absorption of nutrients.

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Crystalloid

A type of fluid that contains electrolytes and other small molecules, allowing it to pass through cell membranes easily.

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Isotonic

Fluid with the same concentration as the body's fluids, resulting in no net movement of water into or out of cells.

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Hypotonic

Fluid with a lower concentration of solutes than the body's fluids, causing water to move into cells and potentially swell them.

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Hypertonic

Fluid with a higher concentration of solutes than the body's fluids, causing water to move out of cells and potentially shrink them.

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Colloid

A solution containing larger molecules, like proteins, that are too big to pass easily through cell membranes.

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Active Transport

Movement of molecules across a cell membrane against their concentration gradient, requiring energy.

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Simple Diffusion

Movement of molecules across a cell membrane from an area of higher concentration to an area of lower concentration, requiring no energy.

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Facilitated Diffusion

Movement of molecules across a cell membrane with the help of transport proteins, requiring no energy.

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Sodium (Na+)

The primary positively charged ion found outside cells (extracellular).

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Sodium Levels

Normal range is 135-145 mEq/L. Hyponatremia is too low, hypernatremia is too high.

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Calcium (Ca++)

Found in both cells (intracellular) and fluids outside cells (extracellular), with the majority (90%) stored in teeth.

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Calcium Levels

Normal range is 22 to 25 mEq/L or 4.25 to 5.25 mg/dL. Hypocalcemia is too low, hypercalcemia is too high.

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Magnesium (Mg++)

Mostly found within cells (intracellular) and plays a key role in nerve and muscle function.

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Magnesium Levels

Normal range is 1.5 to 2.5 mEq/L.

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Hyperkalemia

Elevated potassium levels in the blood.

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Hypotonic Fluid

Solutions with a lower concentration of dissolved particles compared to the blood.

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What is filtration?

The process of removing waste products, salts, and excess fluid from the blood in the glomerulus.

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What is reabsorption?

The process of taking back useful substances from the filtered fluid in the tubules and returning them to the blood.

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Urine Formation

The creation of urine in the kidneys, involving three main steps: filtration, reabsorption, and secretion.

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What is secretion?

The process of adding unwanted substances from the blood into the filtered fluid in the tubules.

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Normal Urine Composition

Urine is mostly water (96%), with dissolved substances like urea, salts, sulfates, and phosphates.

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Abnormal Constituents of Urine

These are substances that shouldn't be found in urine, like white blood cells, fat, glucose, casts, bile, hemoglobin, and red blood cells.

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What are changes in urine production?

Changes in urine production can include changes in color, appearance, odor, concentration, and the presence of cells or chemical constituents.

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Routine Urinalysis Procedure

A standard test that involves physically examining the urine, including its color, transparency, and chemical analysis using reagent strips.

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What is a random (spot) specimen?

Urine collected at any time.

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Fasting/timed specimens

Urine collected after a specific period of time without eating, used to measure substances without food interference.

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Catheterized specimen

Urine collected directly from the bladder using a sterile tube inserted through the urethra, ensuring a non-contaminated sample.

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Midstream catch

Urine collected mid-stream after initial flow is discarded, reducing contamination from the urethra.

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What is a refractometer?

An instrument used to measure the specific gravity of urine, a measure of its concentration.

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How do you prepare urine for microscopic examination?

Centrifuge the urine to separate the sediment, then pour off the liquid and resuspend the sediment for examination under a microscope.

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Mechanical Digestion

The process of physically breaking down food into smaller pieces using muscle force.

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Chemical Digestion

The process of chemically breaking down food using enzymes and other secretions.

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Peristalsis

Wave-like muscle contractions that propel food through the digestive tract.

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What are the 4 major folds of the peritoneum?

The four major folds of the peritoneum are the lesser omentum, greater omentum, transverse mesocolon, and mesentery proper.

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Mesentery

A fold of tissue that helps hold abdominal organs in place and contains blood vessels, nerves, and lymphatics.

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What does the lesser omentum connect?

The lesser omentum connects the stomach to the liver.

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What does the greater omentum do?

The greater omentum hangs over the abdominal organs, protecting them and helping with immune responses.

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Salivary Glands

Three pairs of glands that secrete saliva into the mouth, initiating chemical digestion and moistening food.

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What is the function of salivary amylase?

Salivary amylase breaks down carbohydrates into smaller sugars.

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What is the function of teeth?

Teeth are used to tear, grind, and mechanically break down food.

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Swallowing Phases

The process of swallowing involves three phases: the voluntary phase, the pharyngeal phase, and the esophageal phase.

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What is the esophagus?

The esophagus is a muscular tube that connects the pharynx to the stomach, propelling food through peristalsis.

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What are the regions of the stomach?

The stomach is divided into the cardia, fundus, body, antrum, and pylorus.

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What does the pyloric sphincter do?

The pyloric sphincter controls the movement of chyme from the stomach into the small intestine.

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Gastric Juice

A mixture of secretions produced by the stomach glands, including hydrochloric acid, pepsinogen, and mucus.

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Study Notes

Urinary Formation

  • Urine is formed in the kidneys and excreted through the urethra.
  • The urinary system consists of kidneys, ureters, bladder, and urethra.
  • The kidneys filter waste products, salts, and excess fluid from the blood.
  • Tubules concentrate the filtered material.
  • Nephrons, consisting of glomeruli and tubules, make up the functional units of the kidneys.
  • One million nephrons exist in each kidney.
  • Substances, like water, ammonia, electrolytes, glucose, amino acids, creatinine, and urea are filtered out from the body.
  • Urine production can vary (increase or decrease) depending on the body's needs.
  • Urine color and odor can change.
  • Abnormal constituents in urine can include white blood cells, fats, glucose, casts, bile, hemoglobin, and red blood cells.
  • Urine concentration (specific gravity) can vary.

Urine Composition

  • Urine is primarily water (96%) and dissolved substances (4%).
  • Dissolved substances include urea, salts, sulfates, and phosphates.
  • Abnormal constituents of urine can include white blood cells, fats, glucose, casts, bile, hemoglobin and red blood cells.

Filtration

  • Glomeruli filter waste products, salts, and excess fluid from the blood.
  • Tubules concentrate the filtered substances.
  • Common substances in urine include water, ammonia, electrolytes, glucose, amino acids, creatinine, and urea.
  • Chemical constituents within urine may change.

Secretion

  • Substances not already filtered are secreted in the urine.
  • Substances like hydrogen and ammonium ions may be secreted into the urine in exchange for sodium.

Reabsorption

  • About 180 liters of filtrate are produced daily.
  • The body reabsorbs most of the filtrate.
  • Blood cells and proteins stay in the blood.
  • Glucose is reabsorbed if blood glucose is below 180 mg/dl.

Safety

  • Standard precautions are necessary during urine collection.
  • Transmission precaution procedures are needed.
  • Biohazard precautions are also necessary.
  • Proper disposal of urine is a safety consideration.

Quality Control

  • Regulatory agencies oversee testing protocols.
  • Testing records are maintained.
  • Instruments are recalibrated.

Urine Containers

  • Sterile containers are needed for cultures.
  • Preservative may be added to 24-hour collection containers.

Urine Collection

  • Specimens should be labeled immediately after collection with patient information, date, time, physician's name, and identifier.
  • Random specimens, concentrated specimens (first specimen of the day), fasting specimens, and catheterized specimens are collected for various purposes.
  • Fasting specimens may require directions and specific lengths of fast from patients.
  • Collection and testing should follow correct procedures for reliable results.

Examination of Urine

  • Examining urine should be done promptly, preferably within 30 minutes.
  • Refrigerate if testing is delayed.
  • Urine specimens should be observed for color, clarity, and odor before testing.

Routine Urinalysis Procedure

  • Physical examination of urine, including observations of color and clarity, is documented.

Urine Sediment Cells and Microsopic

  • Examination of urine sediment cells, including red blood cells, white blood cells, and other components, is performed.
  • Parasite and bacteria identification is commonly conducted.
  • Crystal identification in urine specimens is also a part of the examination.

Urine Crystals

  • Common urine crystals include uric acid, cysteine, and crystals related to drug usage.

Urine Report

  • An urinalysis report includes patient information, specimen type, method of collection, ordering provider, medical assistant name, date and time of collection, time of testing, and findings.

Drug Screening

  • Drug screening, testing protocol follows chain-of-custody procedures, and is essential for various purposes (e.g. employment).
  • Results from urine drug screening are typically evaluated against documented guidelines and legal protocols.

Digestive System

  • Digestion involves breaking down ingested food.
  • Secretion, mixing and propulsion, absorption and excretion are essential components of the digestive process.
  • Organs of the digestive system include digestive tract, accessory digestive organs such as liver, pancreas, gallbladder, salivary glands.
  • Mechanical digestion uses force, while chemical digestion uses enzymes and other secretions.
  • The digestive system includes mouth, pharynx, esophagus, stomach, small intestine, and large intestine.

Gastrointestinal Tract

  • The GI tract is a continuous tube.
  • Secretions are involved in digestive processes.

Peristalsis

  • Sequential muscle contractions move food through the digestive tract.

Nerve Supply

  • The central nervous system initiates digestive processes like salivation, and the enteric nervous system controls the movement of materials within the GI tract.
  • The autonomic nervous system modulates the speed of GI motility and secretion.

Blood Supply

  • Nutrients are delivered from the GI tract after absorption.
  • Blood vessels remove waste products.

The Peritoneum

  • This serous membrane supports abdominal organs, and helps to reduce friction between organs

Accessory Organs

  • Accessory organs (teeth, tongue, salivary glands, pancreas, liver, and gallbladder) support digestion by breaking down and processing food.

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