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Questions and Answers

What is the impact of disrupting the mitochondrial membrane on ATP production?

  • ATP production ceases as the proton gradient is disrupted. (correct)
  • ATP production shifts to the nucleus.
  • ATP production increases due to enhanced proton gradient.
  • ATP production is unaffected because mitochondria have alternative pathways.

How does inhibiting ribosome function affect a cell's activities?

  • The cell can no longer synthesize proteins, disrupting normal function. (correct)
  • The cell begins replicating DNA at an accelerated rate.
  • The cell increases its rate of lipid metabolism.
  • The cell switches to using lipids as the primary energy source.

What is the consequence if an enzyme's active site is blocked?

  • The enzyme's production will halt.
  • The enzyme will be unable to bind its substrate and thus cannot catalyze the reaction. (correct)
  • The enzyme will catalyze reactions at a slower rate.
  • The enzyme will catalyze different reactions.

What is the effect of inhibiting DNA polymerase during the S phase?

<p>DNA replication is halted, potentially leading to cell cycle arrest or cell death. (B)</p> Signup and view all the answers

How would disrupting the function of the Golgi apparatus impact a cell reliant on protein secretion?

<p>The cell will be unable to properly modify and package proteins for secretion. (B)</p> Signup and view all the answers

What is the effect of disrupting peptide bonds in a protein?

<p>The protein's primary structure is disrupted, leading to loss of function. (B)</p> Signup and view all the answers

If mRNA is unable to leave the nucleus, what cellular process is directly hindered?

<p>Protein synthesis in the cytoplasm is inhibited because the genetic code cannot be read by ribosomes. (D)</p> Signup and view all the answers

How does the disruption of tRNA's function affect protein synthesis?

<p>tRNA disruption prevents amino acids from being delivered to ribosomes, halting protein synthesis. (A)</p> Signup and view all the answers

What is the immediate result of inhibiting helicase during DNA replication?

<p>The DNA helix cannot unwind, preventing replication. (B)</p> Signup and view all the answers

If the Golgi apparatus malfunctions, how does this affect protein secretion in a cell?

<p>Proteins are secreted without proper modifications or sorting. (C)</p> Signup and view all the answers

How does the presence of multiple alleles for a single gene affect the possible genotypes and phenotypes in a population?

<p>It increases both the number of possible genotypes and phenotypes. (A)</p> Signup and view all the answers

What is the expected phenotypic ratio of a monohybrid cross if incomplete dominance is involved?

<p>1:2:1, reflecting the blending of traits (D)</p> Signup and view all the answers

How can you distinguish between Down syndrome and Turner syndrome based on karyotype analysis?

<p>Down syndrome shows an extra chromosome 21, while Turner syndrome shows a single X chromosome. (D)</p> Signup and view all the answers

Consider a cross between two individuals with genotypes AaBbCc and AabbCc, assuming independent assortment. What is the probability of an offspring having the genotype AAbbcc?

<p>1/32 (A)</p> Signup and view all the answers

How does crossing over during meiosis contribute to genetic diversity?

<p>It allows for the exchange of genetic material between homologous chromosomes. (B)</p> Signup and view all the answers

What distinguishes an exon from an intron, and how does this affect gene expression?

<p>Exons are coding regions, while introns are non-coding regions that are spliced out before translation. (C)</p> Signup and view all the answers

What is the predicted consequence of a nonsense mutation early in the coding sequence of a gene?

<p>A non-functional or truncated protein due to premature termination of translation. (C)</p> Signup and view all the answers

How does aneuploidy typically arise, and what is its impact on the resulting organism?

<p>Aneuploidy arises from nondisjunction during meiosis and can cause developmental abnormalities. (B)</p> Signup and view all the answers

How is PCR used to diagnose viral infections quickly, such as COVID-19?

<p>PCR amplifies specific viral DNA or RNA sequences, making them detectable even in low concentrations. (B)</p> Signup and view all the answers

What are the broader implications of using restriction enzymes in genetic engineering beyond just cutting DNA?

<p>Restriction enzymes enable the creation of recombinant DNA molecules, crucial for gene cloning and genetic engineering. (C)</p> Signup and view all the answers

What is the potential outcome of damage to the cerebellum?

<p>Impaired balance and coordination. (A)</p> Signup and view all the answers

How would impaired nephron function directly affect the body?

<p>Inability to properly filter waste from the blood. (B)</p> Signup and view all the answers

What is the physiological significance of cardiac muscle having intercalated discs?

<p>They allow rapid and coordinated contraction of heart muscle. (B)</p> Signup and view all the answers

How does the structure of arteries contribute to maintaining blood pressure?

<p>Their elastic walls stretch and recoil, helping to smooth out blood flow. (A)</p> Signup and view all the answers

If the small intestine's absorptive surface is reduced, what specific nutritional deficiencies might arise?

<p>All of the above. (D)</p> Signup and view all the answers

What compensatory mechanisms does the body employ when insulin secretion is insufficient?

<p>Increased glucagon production, stimulating the liver to release more glucose. (D)</p> Signup and view all the answers

How does emphysema, which damages alveoli, affect blood oxygen levels?

<p>It decreases the surface area for gas exchange, reducing oxygen levels. (A)</p> Signup and view all the answers

How does damage to dendrites affect neuronal communication?

<p>It impairs the neuron's ability to receive signals. (A)</p> Signup and view all the answers

What are the potential consequences of extensive damage to the skin from a severe burn?

<p>Dehydration and increased risk of infection. (D)</p> Signup and view all the answers

What would be the impact of a damaged left ventricle on the circulatory system?

<p>Oxygenated blood cannot be effectively pumped to the body. (C)</p> Signup and view all the answers

How would the immune response to tuberculosis differ in individuals with HIV?

<p>The immune response is suppressed, increasing the risk of developing active tuberculosis. (B)</p> Signup and view all the answers

How does the mechanism of action differ between antiviral drugs that target influenza and antibiotics that target bacterial infections?

<p>Antiviral drugs interfere with viral replication inside host cells, whereas antibiotics target bacterial structures and metabolic pathways. (A)</p> Signup and view all the answers

In an individual with a compromised or absent thymus, what aspects of the immune system would be most affected?

<p>The maturation and differentiation of T-cells would be impaired. (B)</p> Signup and view all the answers

How would the long-term use of broad-spectrum antibiotics affect the B-cell population?

<p>Reduce the diversity of antigens it is able to protect against (B)</p> Signup and view all the answers

In an autoimmune disease like rheumatoid arthritis, how does the immune system mistakenly attack the body's own tissues?

<p>By failing to differentiate between self and non-self antigens due to a breakdown in immune tolerance. (A)</p> Signup and view all the answers

What type of immune response is primarily stimulated by vaccines, and how does this provide long-term protection?

<p>Adaptive immunity, by inducing the formation of memory cells that can mount a rapid response upon subsequent exposure. (C)</p> Signup and view all the answers

When macrophages fail to engulf pathogens effectively, what subsequent immune responses might be compromised?

<p>All of the above. (D)</p> Signup and view all the answers

If the mosquito population carrying Plasmodium falciparum (malaria) is effectively controlled, what broader ecological effects might be anticipated?

<p>A shift disease ecology and different disease vectors become more prominent. (A)</p> Signup and view all the answers

How can a Gram stain identify the presence of Staphylococcus aureus?

<p>Through the characteristic stain absorption indicating a thick peptidoglycan layer. (C)</p> Signup and view all the answers

What is the critical difference between a bacterium and an antigen?

<p>Bacteria are living cells that can replicate, while antigens are molecules that trigger an immune response. (B)</p> Signup and view all the answers

How does natural selection primarily act on genetic variation within a population?

<p>Natural selection favors traits that enhance survival and reproduction in a specific environment. (D)</p> Signup and view all the answers

Flashcards

Mitochondrion

Organelle responsible for ATP production.

Protein synthesis

The process of creating proteins.

Proteins (as enzymes)

Macromolecules that catalyze biochemical reactions.

S phase

The stage when DNA is duplicated.

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Endomembrane system

A cellular network excluding mitochondria.

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Peptide bond

Connects amino acids in proteins.

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mRNA

Carries genetic code from nucleus to ribosomes.

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tRNA

Transports amino acids to the ribosome.

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Helicase

Unwinds the DNA helix during replication.

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Golgi apparatus function

Modifies and packages proteins.

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Alleles

Variations of the same gene.

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Dominant allele

The expressed allele in heterozygotes.

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Down syndrome

Trisomy 21.

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aa offspring probability (Aa x Aa)

Probability is 25%.

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Crossing over

Shuffles genes between homologous chromosomes.

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Gene

Codes for a protein.

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Nonsense mutation

Mutation resulting in a stop codon.

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Aneuploidy

Abnormal chromosome number.

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Polymerase chain reaction (PCR)

Amplifies DNA.

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Restriction enzymes

Cuts DNA at specific sequences.

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Cerebellum

Regulates balance and coordination.

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Nephron

Functional unit of the kidney.

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Cardiac muscle

Involuntary and striated muscle tissue.

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Arteries

Carry oxygenated blood away from heart.

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Small intestine

Main region for nutrient absorption.

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Insulin

Lowers blood glucose levels.

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Alveoli

Site of gas exchange in lungs.

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Dendrite

Receives incoming signals.

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Skin

The largest organ in the body.

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Left ventricle

Pumps oxygenated blood to body.

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Tuberculosis cause

Bacterium.

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Influenza

A viral disease.

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First line of defense

Include skin and mucous membranes.

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B-cells

Primarily produce antibodies.

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Rheumatoid arthritis

An autoimmune disease.

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Vaccines

Stimulate antibody production.

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Macrophages

Engulfs pathogens.

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Malaria

Causative agent is a protozoan.

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Staphylococcus aureus

Gram-positive.

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Antigen

Triggers an immune response.

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Study Notes

Cell Biology & Molecular Biology

  • Mitochondria are responsible for ATP production.
  • Ribosomes' primary function is protein synthesis.
  • Proteins primarily catalyze biochemical reactions.
  • DNA replication occurs during the S phase of the cell cycle.
  • Mitochondria are not a component of the endomembrane system.
  • Peptide bonds connect amino acids in proteins.
  • mRNA carries genetic information from the nucleus to the cytoplasm.
  • tRNA carries amino acids to ribosomes during protein synthesis.
  • Helicase unwinds the DNA helix during replication.
  • The Golgi apparatus modifies and packages proteins.

Genetics

  • Alleles are different forms of a gene.
  • In a heterozygous individual, the dominant allele is expressed.
  • Down syndrome is caused by a trisomy of chromosome 21.
  • The probability of two heterozygous parents (Aa) having a homozygous recessive child (aa) is 25%.
  • Crossing over increases genetic diversity during meiosis.
  • A gene is a segment of DNA that codes for a protein.
  • A nonsense mutation results in a premature stop codon.
  • Nondisjunction during meiosis results in aneuploidy.
  • Polymerase chain reaction (PCR) amplifies DNA sequences.
  • Restriction enzymes cut DNA at specific sequences.

Human Anatomy & Physiology

  • The cerebellum regulates balance and coordination.
  • The nephron is the functional unit of the kidney.
  • Cardiac muscle tissue is involuntary and striated.
  • Arteries carry oxygen-rich blood away from the heart.
  • The small intestine is the primary site of nutrient absorption in the digestive system.
  • Insulin lowers blood glucose levels.
  • The exchange of gases in the lungs occurs in the alveoli.
  • Dendrites receive incoming signals in a neuron.
  • The skin is the largest organ in the human body.
  • The left ventricle pumps oxygenated blood to the body.

Microbiology & Immunology

  • Bacteria are responsible for tuberculosis.
  • Influenza is a viral disease.
  • Skin and mucous membranes are the first line of defense in the immune system.
  • B-cells are primarily responsible for producing antibodies.
  • Rheumatoid arthritis is an autoimmune disease.
  • Vaccines stimulate the production of antibodies.
  • Macrophages engulf pathogens.
  • Protozoa cause malaria.
  • Staphylococcus aureus is a gram-positive bacterium.
  • An antigen is a substance that triggers an immune response.

Ecology & Evolution

  • Natural selection is the process by which organisms better adapted to their environment survive and reproduce more offspring.
  • Flippers of a dolphin and arms of a human are homologous structures.
  • The founder effect is an example of genetic drift.
  • Biodiversity describes the variety of life in the world or in a particular habitat.
  • An organism's niche is its role in its environment.
  • Disease is a density-dependent factor affecting population growth.
  • Mutualism is a symbiotic relationship where both species benefit.
  • The tundra biome is characterized by low temperatures and permafrost.
  • Plants are typically the primary producers in an ecosystem.
  • Carbon dioxide is most associated with the greenhouse effect.

Anatomy and Physiology

  • The vertebral column is part of the axial skeleton.
  • Hemoglobin is primarily responsible for transporting oxygen.
  • Adrenaline is produced by the adrenal medulla.
  • The sinoatrial (SA) node is located in the right atrium.
  • The cerebrum controls voluntary muscle movements.
  • The lobule is the functional unit of the liver.
  • Vitamin K is essential for blood clotting.
  • The primary function of the large intestine is to absorb water.
  • The shoulder contains a ball and socket joint.
  • The sinoatrial (SA) node is the primary pacemaker of the heart.

Human Physiology

  • Regulation of body temperature occurs in the hypothalamus.
  • Gas exchange is the primary function of alveoli in the lungs.
  • Glucagon is produced by the pancreas to raise blood glucose levels.
  • The neuron is the structural and functional unit of the nervous system.
  • Platelets are primarily responsible for clotting.
  • Filtration in the kidneys occurs in the glomerulus.
  • Vitamin D is essential for calcium absorption.
  • The cerebrum is the largest part of the human brain.
  • The liver detoxifies harmful substances.
  • The small intestine's primary function is nutrient absorption.

Microbiology & Immunology (cont.)

  • Artificial active immunity is acquired through vaccination.
  • Escherichia coli is a gram-negative bacterium.
  • A virus causes AIDS.
  • T-cells are primarily responsible for cell-mediated immunity.
  • Malaria is caused by a protozoan.
  • Skin is the body's first line of defense against pathogens.
  • Phagocytosis is the process by which a cell engulfs a particle to form an internal compartment.
  • Viruses cannot reproduce independently.
  • Athlete's foot is a fungal disease.
  • B-cells produce antibodies.

Molecular Biology & Genetics

  • Transcription is the process of copying DNA into RNA.
  • Adenine is a purine base found in DNA.
  • The presence of the Y chromosome determines sex in humans.
  • Helicase unwinds the DNA helix during replication.
  • A mutation is a change in the nucleotide sequence of DNA.
  • tRNA carries amino acids to the ribosome during protein synthesis.
  • The phenotype is the observable characteristics of an organism.
  • Blood type AB is an example of a codominant trait.
  • Crossing over involves exchanging segments of DNA between homologous chromosomes.
  • DNA has a double-stranded helix structure.

Cell Biology

  • Mitochondria are known as the powerhouse of the cell.
  • The fluid mosaic model describes the structure of the plasma membrane.
  • Ribosomes are responsible for protein synthesis.
  • Cytokinesis involves the division of the cytoplasm.
  • Chloroplasts are found in plant cells but not in animal cells.
  • Phagocytosis is the process by which cells engulf large particles.
  • The Golgi apparatus modifies, sorts, and packages proteins for secretion.
  • Microtubules are involved in cell division.
  • Cytosol is the semi-fluid substance inside the cell membrane.
  • Protein synthesis is not a function of the smooth endoplasmic reticulum.

Ecology

  • A grasshopper is a primary consumer in a food chain.
  • An increase in carbon dioxide primarily causes the greenhouse effect.
  • Permafrost characterizes the tundra biome.
  • A decomposer breaks down dead organic matter.
  • Bees pollinating flowers exemplify mutualism.
  • Carrying capacity is the maximum number of individuals an environment can support.
  • Nitrogen is most abundant in Earth's atmosphere.
  • Excessive nutrients primarily cause eutrophication of water bodies.
  • Coal is a non-renewable resource.
  • Phytoplankton are the primary producers in an aquatic ecosystem.

Evolution & Genetics

  • Charles Darwin proposed the theory of natural selection.
  • The appendix is an example of a vestigial structure in humans.
  • Gene flow refers to the movement of alleles between populations.
  • Homeostasis is not a mechanism of evolution.
  • The Hardy-Weinberg equilibrium describes genetic stability in a population.
  • Speciation that occurs without geographic isolation is called sympatric speciation.
  • Genetic drift is best described as random changes in allele frequencies.
  • Analogous structures indicate convergent evolution.
  • The founder effect is a type of genetic drift.
  • DNA is considered the universal genetic material.

Biochemistry

  • Sucrose is a disaccharide.
  • Amino acids are the building blocks of proteins.
  • Vitamin K is essential for the synthesis of clotting factors.
  • The primary structure of a protein refers to its sequence of amino acids.
  • Enzymes act as biological catalysts.
  • Catalysis is not a function of lipids.
  • DNA contains thymine.
  • Transcription is the process by which mRNA is synthesized from DNA.
  • ATP is classified as a nucleotide.
  • Adenine is a purine base.

Human Physiology

  • The pancreas produces the hormone insulin.
  • The nephron is the functional unit of the kidney.
  • The cerebellum regulates balance and coordination.
  • The primary function of red blood cells is to transport oxygen.
  • The liver produces bile.
  • Capillaries are the smallest blood vessels in the body.
  • The diaphragm is a muscle that aids in respiration.
  • The liver detoxifies harmful substances.
  • The SA node is the primary pacemaker of the heart.
  • Melatonin regulates the sleep-wake cycle.

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