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Questions and Answers
What is the primary function of sodium in the body?
What is the primary function of sodium in the body?
What is the primary determinant of osmolality in the body?
What is the primary determinant of osmolality in the body?
What is the result of hypernatremia on the body's cells?
What is the result of hypernatremia on the body's cells?
What is the primary protection against hypernatremia?
What is the primary protection against hypernatremia?
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What is the treatment for hypernatremia?
What is the treatment for hypernatremia?
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What is the result of hyponatremia on the body's cells?
What is the result of hyponatremia on the body's cells?
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What is the treatment for hyponatremia caused by water excess?
What is the treatment for hyponatremia caused by water excess?
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What is the treatment for severe hyponatremia symptoms?
What is the treatment for severe hyponatremia symptoms?
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What is the approximate percentage of body weight that is composed of intracellular fluid?
What is the approximate percentage of body weight that is composed of intracellular fluid?
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Which of the following ions is most prevalent in the interstitial fluid?
Which of the following ions is most prevalent in the interstitial fluid?
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What is the primary mechanism by which water moves from an area of high concentration to an area of low concentration?
What is the primary mechanism by which water moves from an area of high concentration to an area of low concentration?
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What is the term for the movement of water into a cell due to a higher concentration of solutes outside the cell?
What is the term for the movement of water into a cell due to a higher concentration of solutes outside the cell?
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What is the term for the movement of water out of a cell due to a higher concentration of solutes inside the cell?
What is the term for the movement of water out of a cell due to a higher concentration of solutes inside the cell?
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What is the term for the movement of water into a cell due to an equal concentration of solutes inside and outside the cell?
What is the term for the movement of water into a cell due to an equal concentration of solutes inside and outside the cell?
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What is the primary mechanism by which sodium is kept out of the cell and potassium is kept in the cell?
What is the primary mechanism by which sodium is kept out of the cell and potassium is kept in the cell?
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What is the term for the osmotic pressure exerted by colloids in a solution?
What is the term for the osmotic pressure exerted by colloids in a solution?
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What is the result of fluid shifting from the plasma to the interstitial space?
What is the result of fluid shifting from the plasma to the interstitial space?
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Which of the following is a cause of fluid shifting from the plasma to the interstitial space?
Which of the following is a cause of fluid shifting from the plasma to the interstitial space?
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What is the primary cause of hypoproteinemia?
What is the primary cause of hypoproteinemia?
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Which of the following is a sign of hyperkalemia?
Which of the following is a sign of hyperkalemia?
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What is the primary treatment for hypovolemia?
What is the primary treatment for hypovolemia?
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Which of the following is a nursing diagnosis for hypervolemia?
Which of the following is a nursing diagnosis for hypervolemia?
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What is the purpose of daily weights in patients with fluid imbalances?
What is the purpose of daily weights in patients with fluid imbalances?
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Which of the following electrolyte imbalances is associated with muscle twitching?
Which of the following electrolyte imbalances is associated with muscle twitching?
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What is the primary cause of hypervolemia?
What is the primary cause of hypervolemia?
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Which of the following is a clinical manifestation of hypoproteinemia?
Which of the following is a clinical manifestation of hypoproteinemia?
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What is the primary treatment for hypervolemia?
What is the primary treatment for hypervolemia?
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Which of the following is a sign of hyponatremia?
Which of the following is a sign of hyponatremia?
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Study Notes
Fluid Compartments
- There are three main fluid compartments: intracellular fluid (ICF), extracellular fluid (ECF), and transcellular fluid.
- Intracellular fluid (ICF) is the fluid within cells, making up 42% of body weight and 2/3 of body water.
- Extracellular fluid (ECF) is the fluid outside cells, divided into intravascular (plasma) and interstitial fluid (between cells, including lymph).
- Transcellular fluid is a small but important fluid compartment, making up approximately 1 liter.
Intracellular Fluid (ICF)
- ICF is the fluid within cells, making up 42% of body weight and 2/3 of body water.
- Potassium (K+) is the most prevalent intracellular cation.
- Phosphate (PO4-) is the most prevalent intracellular anion.
Extracellular Fluid (ECF)
- ECF is the fluid outside cells, divided into intravascular (plasma) and interstitial fluid (between cells, including lymph).
- Chloride (Cl-) is the most prevalent anion in interstitial fluid.
- Sodium (Na+) is the most prevalent cation in interstitial fluid.
- 2/3 of ECF is in interstitial fluid, and 1/3 is intravascular.
Transcellular Fluid
- Transcellular fluid is a small but important fluid compartment, making up approximately 1 liter.
- It includes cerebrospinal fluid (CSF), gastrointestinal (GI) tract fluid, pleural space fluid, synovial spaces, and peritoneal space fluid.
Mechanisms Controlling Fluid and Electrolyte Movement
- Diffusion: the movement of molecules from an area of high concentration to an area of low concentration.
- Facilitated diffusion: the movement of molecules with the help of carrier molecules.
- Active transport: the movement of molecules against their concentration gradient, requiring energy (e.g., keeping sodium out and potassium in cells, using ATP).
Osmosis and Hydrostatic Pressure
- Osmosis: the movement of water between compartments separated by a membrane, from an area of high water concentration to an area of low water concentration.
- Hydrostatic pressure: the force within a fluid compartment.
- Oncotic pressure (colloid osmotic pressure): the osmotic pressure exerted by colloids (e.g., proteins) in a solution, pulling fluid into the vascular space.
Fluid Shifts and Edema
- Fluid shifts can occur from plasma to interstitial space, resulting in edema.
- Causes of fluid shifts include elevated venous hydrostatic pressure, decreased plasma oncotic pressure, and elevated interstitial oncotic pressure.
Electrolyte Disorders
- Electrolyte imbalances can occur due to excess or deficit of sodium, potassium, calcium, and magnesium.
- Signs and symptoms of electrolyte disorders vary depending on the specific electrolyte and whether it is in excess or deficit.
Protein Imbalances
- Plasma proteins, especially albumin, are important determinants of plasma volume.
- Hyperproteinemia is rare and occurs with dehydration-induced hemoconcentration.
- Hypoproteinemia can occur due to various causes, including anorexia, malnutrition, starvation, fad dieting, poorly balanced vegetarian diets, poor absorption, inflammation, and hemorrhage.
Hypoproteinemia Clinical Manifestations
- Edema due to insufficient oncotic pressure.
- Slow healing, anorexia, fatigue, anemia, muscle loss, and ascites.
- Management involves a high-carbohydrate, high-protein diet, dietary protein supplements, and enteral or total parenteral nutrition.
Extracellular Fluid Volume Imbalances
- Hypovolemia can occur due to loss of normal body fluids, decreased intake, or plasma-to-interstitial fluid shift.
- Hypervolemia can occur due to excessive intake, abnormal retention of fluids, or interstitial-to-plasma fluid shift.
- Management involves fluid replacement, diuretics, and fluid restriction.
Nursing Diagnoses and Implementation
- Nursing diagnoses for hypervolemia include excess fluid volume, ineffective airway clearance, risk for impaired skin integrity, and disturbed body image.
- Nursing diagnoses for hypovolemia include fluid volume deficit, decreased cardiac output, and risk for impaired skin integrity.
- Nursing implementation involves monitoring intake and output, cardiovascular status, respiratory status, neurological function, and daily weights, as well as assessing skin turgor and edema.
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