L3.1 - control of food intake (II)

if energy levels are low, AMPK is activated to create pathways to generate ATP

CCK,GLP-1 and PPY

amylin is released to repress glucagon by decreasing food intake centrally and delaying gastric emptying which sends signals to the hypothalamus that theres is enough food in the stomach

<p>They inhibit AgRP/NPY suppressing food intake</p> Signup and view all the answers

<p>Ghrelin activates NPY/AgRP to increase food intake.</p> Signup and view all the answers

<p>leptin</p> Signup and view all the answers

<p>leptin is released from adipose tissue and is dependent on the release of insulin. increased leptin levels signal to the brain that the body has enough energy storage therefore inhibiting food intake and increasing energy</p> Signup and view all the answers

<p>dysregulation of leptin can result in low leptin levels which tricks the brain into thinking the body is starved which leads to over eating and excess fat storage</p> Signup and view all the answers

<p>in diet-ralated obesity, the overconsumption of saturated fatty acids causes leakage out of the blood brain barrier causing inflammatory responses in the hypothalamic neurons making them unresponsive to leptin.</p> Signup and view all the answers

<p>when high leptin levels are interpreted as low triggering the starvation response (fat storage and increase of food intake)</p> Signup and view all the answers