Lecture 21: Making eggs and sperm

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Questions and Answers

What triggers ovulation?

  • Peak in follicle-stimulating hormone (FSH)
  • Peak in luteinising hormone (LH) (correct)
  • Peak in progesterone levels
  • Peak in oestrogen levels

What are the two main hormones secreted by the corpus luteum?

  • GnRH and FSH
  • Testosterone and inhibin
  • Progesterone and a small amount of oestrogen (correct)
  • Oestrogen and inhibin

What happens to GnRH secretion during puberty in males?

  • It remains the same
  • It increases (correct)
  • It decreases
  • It stops

What is the result of hypothalamus maturation in males?

<p>Reduced sensitivity to testosterone and inhibin (B)</p> Signup and view all the answers

What is the age range for the onset of puberty in females?

<p>11-13 years old (C)</p> Signup and view all the answers

What is the effect of oestrogen and progesterone on GnRH and LH/FSH secretion before puberty in females?

<p>Inhibits GnRH and LH/FSH secretion (B)</p> Signup and view all the answers

What happens to the reproductive organs during puberty in both males and females?

<p>They increase in size (D)</p> Signup and view all the answers

What is the outcome of maturation of the hypothalamus in females?

<p>Increased GnRH secretion (D)</p> Signup and view all the answers

What is the purpose of mitosis?

<p>To proliferate somatic cells (C)</p> Signup and view all the answers

What is the main difference between mitosis and meiosis?

<p>All of the above (D)</p> Signup and view all the answers

Where does fertilization normally occur?

<p>In the uterine tube (D)</p> Signup and view all the answers

What is the function of the epididymis?

<p>To mature sperm (A)</p> Signup and view all the answers

What is the primary function of the seminal vesicles?

<p>To provide nutrients to sperm (D)</p> Signup and view all the answers

What is the function of the prostate gland?

<p>To provide energy to sperm (B)</p> Signup and view all the answers

What is the function of the bulbourethral glands?

<p>To lubricate the urethra (D)</p> Signup and view all the answers

What is the approximate length of the vas deferens?

<p>45cm (B)</p> Signup and view all the answers

What is the composition of semen?

<p>60% seminal vesicles, 30% prostate, 5% testes, 5% bulbourethral glands (A)</p> Signup and view all the answers

What is the role of Sertoli cells in the seminiferous tubules?

<p>To nourish developing germ cells (C)</p> Signup and view all the answers

What is the final stage of spermatogenesis?

<p>Differentiation of sperm cells (B)</p> Signup and view all the answers

Where do oocytes pause during meiosis?

<p>Prophase I (C)</p> Signup and view all the answers

How many oocytes are present at birth?

<p>400 000 (B)</p> Signup and view all the answers

What is the structure that surrounds the oocyte in a primary follicle?

<p>Granulosa cells (D)</p> Signup and view all the answers

What is the fate of the majority of oocytes in the ovaries?

<p>They undergo atresia (A)</p> Signup and view all the answers

What is the purpose of the epididymis in the male reproductive system?

<p>To store and mature sperm cells (D)</p> Signup and view all the answers

What is the term for the process by which sperm cells are formed?

<p>Spermatogenesis (D)</p> Signup and view all the answers

Study Notes

Cell Division

  • Mitosis: 4 stages, occurs in somatic cells, produces 2 diploid daughter cells, chromosome number remains the same, purpose is cellular proliferation
  • Meiosis: 8 stages, occurs in germ/sex cells, produces 4 haploid daughter cells, chromosome number is halved in each daughter cell, purpose is sexual proliferation

Female Reproductive System

  • Ovaries open into the peritoneal cavity
  • Fimbriae direct ovum into the uterine tube/fallopian tube/oviduct
  • Successful fertilization normally occurs in the first third of the uterine tube
  • Vagina: channel connecting to the cervix

Male Reproductive System

  • Testis and scrotum: contains epididymis for maturation
  • Vas deferens or ductus deferens: approximately 45cm long, has peristaltic movement, contains blood vessels and nerves
  • Urethra: channel connecting to the penis
  • Seminal vesicles: produce prostaglandin, stimulate motility of sperm, fructose, clotting agents
  • Prostate gland: produces citric acid, proteolytic enzymes
  • Bulbourethral (Cowper's) glands: produce mucous, alkaline fluid

Spermatogenesis

  • Seminiferous tubules in testes: contain germ cells, develop into spermatocytes, nourished by Sertoli cells
  • Spermatogonia: develop into primary spermatocytes (2n), then secondary spermatocytes (n), then spermatids (n)
  • Spermatid differentiation: forms head, acrosome, midpiece, and flagellum
  • Released into the lumen of seminiferous tubules to the epididymis for further maturation

Oogenesis

  • Ovaries: suspended by ligaments, contain oogonia (5 million before birth, 400,000 at birth, 300,000 at puberty)
  • Ovarian follicle: contains oocyte, blood vessels, lymphatic vessels, nerves
  • Primordial follicle: primary oocyte pauses at Prophase I
  • Primary follicle: layers of granulosa cells, zona pellucida
  • Secondary follicle: at puberty, only 400 develop fully
  • Ovulation: triggered by peak in luteinising hormone (LH), completes Meiosis I and pauses during early Meiosis II

Hormones in Males and Females

  • Before puberty: low GnRH, low LH and FSH secretion
  • Puberty: hypothalamus maturation, increased GnRH, LH, and FSH secretion, development of secondary characteristics

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