Accessing FederalRegister.gov and eCFR.gov

Questions and Answers

Why is programmatic access to FederalRegister.gov and eCFR.gov limited?

To prevent aggressive automated scraping

What do you need to complete to request access to FederalRegister.gov and eCFR.gov?

A CAPTCHA (bot test)

How long is a request for access to FederalRegister.gov and eCFR.gov valid for?

Three months

What should you do if you want to request a wider IP range?

Use the 'Site Feedback' button Signup and view all the answers

What type of website is FederalRegister.gov?

An official government website Signup and view all the answers

What is the primary purpose of analytical method validation?

To ensure the reliability and accuracy of test results Signup and view all the answers

What information must be included on a sample label?

Sample identifier, description of sample, and date and time of sampling Signup and view all the answers

What type of records must be maintained in a laboratory?

All of the above, plus test and analysis results, analytical method validation records, and sample identification and storage records Signup and view all the answers

Why is it essential to handle and transfer samples properly?

To prevent sample contamination or degradation Signup and view all the answers

How long must laboratory records be retained?

For a specified period of time, as determined by the company or regulatory requirements Signup and view all the answers

Study Notes

Access to FederalRegister.gov and eCFR.gov

FederalRegister.gov and eCFR.gov limit programmatic access due to aggressive automated scraping.
Human users can request access by completing a CAPTCHA (bot test) to add their IP address to the allowed list.
Access requests are valid for approximately three months before needing to be repeated.

Wider IP Range Requests

To request access for a wider IP range, first request access for the current IP address.
Then, use the "Site Feedback" button (found in the lower left-hand side) to make the request.

Laboratory Procedures

Testing and analysis must adhere to established procedures and protocols to ensure accuracy and reliability

Laboratory Equipment Management

Laboratory equipment must be properly installed, operated, and maintained to prevent errors and contamination
Equipment calibration and standardization records must be maintained, including date, time, and results
Equipment must be cleaned, sanitized, and labeled regularly to prevent contamination and ensure traceability

Analytical Method Validation

Analytical methods must be validated to ensure accuracy, precision, and reliability
Validation involves assessing specificity, linearity, range, accuracy, precision, detection limit, and quantitation limit
Validation records must include method description, validation protocol, results, date, and time of validation

Sample Handling and Identification

Samples must be properly identified and labeled to ensure traceability, including sample identifier, description, date, and time of sampling
Samples must be stored to prevent contamination, degradation, or loss
Samples must be handled and transferred to prevent mix-ups or contamination

Documentation and Record Keeping

Laboratory records must include test and analysis results, calibration and standardization records, analytical method validation records, and sample identification and storage records
Records must be accurate, complete, legible, and retained for a specified period of time
Records must be accessible and available for review during inspections and audits