Pox Virus ʹ Pox in a Box

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Questions and Answers

What is unique about the Pox virus's replication process?

  • It needs to enter the host cell's nucleus
  • It brings its own RNA polymerase to produce proteins (correct)
  • It requires the host cell's DNA polymerase
  • It replicates in the nucleus

What is the characteristic shape of the Pox virus's core?

  • Cylindrical
  • Spherical
  • Dumbbell-shaped (correct)
  • Oval

What is the largest known DNA virus?

  • Smallpox virus
  • Molluscum contagiosum virus
  • Cowpox virus
  • Pox virus (correct)

What is the characteristic feature of the lesions caused by Smallpox virus?

<p>Flesh-colored, dome-shaped, and umbilicated (A)</p> Signup and view all the answers

What is the mode of transmission of Molluscum contagiosum virus in adults?

<p>Through sexual transmission (C)</p> Signup and view all the answers

What is the cause of Cowpox?

<p>Cowpox virus (C)</p> Signup and view all the answers

What is the characteristic feature of the lesions caused by Molluscum contagiosum virus?

<p>Small, painless, and flesh-colored (D)</p> Signup and view all the answers

What is the function of the Pox virus's RNA polymerase?

<p>To produce all the proteins the virus needs (C)</p> Signup and view all the answers

What is the characteristic of the Guarneri inclusion bodies?

<p>They are where the virus replicates (C)</p> Signup and view all the answers

What is the result of a biopsy in cases of Pox virus infection?

<p>It is diagnostic (C)</p> Signup and view all the answers

What is the characteristic feature of Smallpox virus?

<p>It causes lesions that are all the same age (C)</p> Signup and view all the answers

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Study Notes

Pox Virus Characteristics

  • Pox virus is a type of DNA virus that replicates exclusively in the cytoplasm.
  • It brings its own RNA polymerase to produce all the proteins it needs, including DNA polymerase.
  • Forms intracytoplasmic bodies in cells it infects, with type B being the most important.
  • Finding these bodies on a biopsy is diagnostic.

Small Pox Virus (Variola)

  • Causes raised skin lesions on surfaces, with all lesions being the same age.
  • Lesions are more common on the extremities and face than the trunk.

Cow Pox Virus

  • Causes symptoms similar to small pox.

Molluscum Contagiosum Virus

  • Causes flesh-colored, dome-shaped, umbilicated lesions on the trunk.
  • Spread through sexual contact in adults, usually resulting in a single lesion.
  • Can spread diffusely in immunosuppressed individuals.
  • Replicates in the dermis.

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