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Pox Virus ʹ Pox in a Box

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Questions and Answers

What is unique about the Pox virus's replication process?

It needs to enter the host cell's nucleus

It brings its own RNA polymerase to produce proteins (correct)

It requires the host cell's DNA polymerase

It replicates in the nucleus

What is the characteristic shape of the Pox virus's core?

Cylindrical

Spherical

Dumbbell-shaped (correct)

Oval

What is the largest known DNA virus?

Smallpox virus

Molluscum contagiosum virus

Cowpox virus

Pox virus (correct)

What is the characteristic feature of the lesions caused by Smallpox virus?

Flesh-colored, dome-shaped, and umbilicated Signup and view all the answers

What is the mode of transmission of Molluscum contagiosum virus in adults?

Through sexual transmission Signup and view all the answers

What is the cause of Cowpox?

Cowpox virus Signup and view all the answers

What is the characteristic feature of the lesions caused by Molluscum contagiosum virus?

Small, painless, and flesh-colored Signup and view all the answers

What is the function of the Pox virus's RNA polymerase?

To produce all the proteins the virus needs Signup and view all the answers

What is the characteristic of the Guarneri inclusion bodies?

They are where the virus replicates Signup and view all the answers

What is the result of a biopsy in cases of Pox virus infection?

It is diagnostic Signup and view all the answers

What is the characteristic feature of Smallpox virus?

It causes lesions that are all the same age Signup and view all the answers

Study Notes

Pox Virus Characteristics

Pox virus is a type of DNA virus that replicates exclusively in the cytoplasm.
It brings its own RNA polymerase to produce all the proteins it needs, including DNA polymerase.
Forms intracytoplasmic bodies in cells it infects, with type B being the most important.
Finding these bodies on a biopsy is diagnostic.

Small Pox Virus (Variola)

Causes raised skin lesions on surfaces, with all lesions being the same age.
Lesions are more common on the extremities and face than the trunk.

Cow Pox Virus

Causes symptoms similar to small pox.

Molluscum Contagiosum Virus

Causes flesh-colored, dome-shaped, umbilicated lesions on the trunk.
Spread through sexual contact in adults, usually resulting in a single lesion.
Can spread diffusely in immunosuppressed individuals.
Replicates in the dermis.

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