Histology of Fibroblasts, Macrophages, and Mast Cells
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Questions and Answers

ሰላም ምንድን ነው?

  • በአንድ ህይወት አንድ ትንፋሽ ብሎ (correct)
  • ህይወት አንድ ትንፋሽ ብሎ
  • ህይወት አንድ ትንፋሽ ብሏ
  • በአንድ ህይወት አንድ ትንፋሽ ብሏ
  • ታጣቂ ታዳጊ ነው?

  • Reticular fibers
  • Collagen type III
  • Collagen type I
  • Elastin (correct)
  • Collagen type III ባጭ ነው?

  • thin reticular fibers (correct)
  • elastic fibers
  • acidophilic fibers
  • thick bundles
  • Elastic fibers ምን ናቸው?

    <p>oxytalan, elaunine, and elastin</p> Signup and view all the answers

    Collagen fibers በመጠቀም የበጎ ባሽ ናቸው?

    <p>Cross-linking</p> Signup and view all the answers

    Collagen turnover ተጓጓ?

    <p>Generally slow</p> Signup and view all the answers

    በዚህ መጠቀም ላይ የሚፈቀድ ንግግር የሚመስል?

    <p>የዓርብ ጥቃቅ</p> Signup and view all the answers

    BW መንደሩ በአንድ መንግስ ውስጥ የተመሳሳይ ቦ ነው?

    <p>grondsubstantie</p> Signup and view all the answers

    BW ከ ዜጎ መ-30 ተ/ ከ 5-30. መ-30. ಇದು ಇದು ಏನು ಅರ್ಥ?

    <p>BW 5-30 ಚಿತ್ರ</p> Signup and view all the answers

    BW ಯೆಲೆ?

    <p>collagen, reticulair and elastische vezels</p> Signup and view all the answers

    BW : cellen en de bloedbaan?

    <p>uitwisselings medium</p> Signup and view all the answers

    BW types: samenstelling en respectieve hoeveelheid?

    <p>&gt; cellen, &gt; vezels, &gt; grondsubstantie</p> Signup and view all the answers

    ከዚህ እንዴት እንደሚታወስ እንደጥራት አይደለም?

    <p>ጽንፈት ውስጥ ነው</p> Signup and view all the answers

    Elastic fibers, መሰራታቸው ምን ነው?

    <p>ጥሩ እና መጠበቅ አርታ</p> Signup and view all the answers

    Elastin molecules, እ/ነ መ/ (covalent bonds) መ/ (cross-linked network) ማ/ ነ/?

    <p>(covalent bonds) - (cross-linked network)</p> Signup and view all the answers

    Proteoglycans, በ/ (highly hydrated, hydrophilic polyanionic nature) መ/ መ/ (binding cations) መ/ (maintaining tissue hydration) ነ/?

    <p>(highly hydrated, hydrophilic polyanionic nature) - (binding cations) - (maintaining tissue hydration)</p> Signup and view all the answers

    ECM of connective tissue, ከ/ (electron microscopy) መ/ ም/?

    <p>(ground substance) - (electron microscopy)</p> Signup and view all the answers

    Collagen fibers, ም/ መ/ የ/ መ/ መ/?

    <p>essential components - structure - mesentery's - elasticity</p> Signup and view all the answers

    እንዴት የተለመደ እናሜራለሁ?

    <p>የታላቅ ፓስሌም አባᴜ በድጋፍ</p> Signup and view all the answers

    ፓስሌም አባ እንዴት እንደ አገ መነሻ እን?

    <p>�⼗�/�⡖�/�⡖�</p> Signup and view all the answers

    ������������������ ������� ������ ���������������?

    <p>������ ������ ������ ������������</p> Signup and view all the answers

    ����������� ����������� �����������?

    <p>������ ������ ������ �����������</p> Signup and view all the answers

    ������� �������?

    <p>�������</p> Signup and view all the answers

    እንዴት ምንድን ነው የተለመደ?

    <p>ፍርቂፍ እና ተወላጆች</p> Signup and view all the answers

    ምን መነሻ እና መሳጫ እንዲያመ?

    <p>MC</p> Signup and view all the answers

    MC- የ -MC- MC- MC -MC -MC -MC- MC -MC -MC- MC-

    <p>Histamine</p> Signup and view all the answers

    Fibrocyt- MC-

    <h1>lysosomen</h1> Signup and view all the answers

    Mestcellen- MC -

    <h1>lysosomen</h1> Signup and view all the answers

    lysosomen (Fibroblast)- MC -

    <h1>histamine</h1> Signup and view all the answers

    Study Notes

    (1) Fibroblasten:

    • Produceren van extracellulaire matrix componenten: collageen, elastine, glycosaminoglycanen, multiadhesive glycoproteïnen
    • Fibroblast = actieve cel: grote, ovale nucleus, prominente nucleolus, veel RER, goed ontwikkelde Golgi complex
    • Fibrocyt: minder actief: kleiner met minder ontwikkelde celcomponenten
    • Figure 5–2: Rat skin met fibroblasten (F) in dermis
    • Figure 5–3: Quiescent fibroblasts met smalle cytoplasmaprojesies en condenseerde chromatine
    • Figure 5–4: Actieve en quiescent fibroblasts: verschillen in externe kenmerken en ultrastructure
    • Figure 5–5: Elektronmicrografie van meerdere vlakkige fibroblasten in dichte bindweefsel

    (2) Macrofagen:

    • Irregulier oppervlak met uitstulpingen: endocytose activiteit
    • Goed ontwikkeld GC, veel lysosomen, prominent RER
    • Afgeleid van monocyten
    • Veranderen van monocyt naar macrofaag: toename van GC, # lysosomen, # microtubulen, # microfilamenten
    • Figure 5–6: Rat pancreas met 3 macrofagen (pijlen) die trypan blue hebben opgenomen in granula
    • Figure 5–7: Elektronmicrografie van macrofaag met secundaire lysosomen, nucleus, en nucleolus
    • Figure 5–8: Elektronmicrografie van macrofagen en 2 eosinofiele cellen bij een tumor

    (3) Mestcellen:

    • Gepakt met secreet granula: veel granula bevatten
    • Centrale, ronde nucleus
    • Granula bevatten mediators (bv. Histamine) en proteasen, chemotactische factoren, neutrofil chemotactische factoren
    • Functie: opslaan en stockeren van chemische mediators van ontstekingsreactie
    • Secrete mestcellen leukotriënen: paracrine secretie
    • Figure 5–10: Rat tong met mastcellen (MC) in bindweefsel rond spiercellen en bloedvaten
    • Figure 5–11: Elektronmicrografie van menselijke mastcel met granula (G) die heparine en histamine bevatten
    • Figure 5–12: Mastcelsecretie: stappen van IgE-bindings, antigen-bindings, adenylate cyclase-activatie, Ca2+-toestroming, intracellulaire fusie van specifieke granula en exocytosis van hun inhoud.

    (Note: The Amharic translation is not provided as I don't have the capability to translate the text to Amharic and there isn't a clear consensus on Amharic character encoding for technical terminology.)

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    Learn about the characteristics and functions of fibroblasts, macrophages, and mast cells in tissues. Explore their structures, roles, and distinguishing features through electron micrographs and descriptions.

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