Pharmacology: Quinidine Metabolism and Drug Interactions Quiz
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Questions and Answers

What is the primary route of elimination for quinidine?

  • Biliary excretion
  • Pulmonary excretion
  • Renal excretion (correct)
  • Sweat excretion
  • Which enzyme is primarily responsible for the metabolism of quinidine?

  • CYP3A4
  • CYP2C9
  • CYP1A2
  • CYP2D6 (correct)
  • What is a potential consequence of co-administration of quinidine with drugs metabolized by CYP2D6?

  • Decreased risk of drug-drug interactions
  • Reduced risk of adverse effects due to enhanced metabolism
  • Increased risk of toxicity due to decreased metabolism (correct)
  • No interaction with CYP2D6 substrates
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