10 Questions
What are the two larger peptide chains in an IgG molecule called?
Heavy (H) chains and Light (L) chains
Which Greek letter is used to denote the heavy chains of IgG?
Gamma (γ)
What is the molecular weight of the heavy chains in an IgG molecule approximately?
50,000
Which type of peptide chains can the light chains in an IgG molecule be?
Kappa (κ) chains or Lambda (λ) chains
How do the kappa and lambda light chains differ?
By amino acid substitutions along their length
What breaks the sulfhydryl bonds holding the heavy and light chains in an IgG molecule together?
Reductant like mercaptoethanol
Which forces hold the heavy and light chains together in an IgG molecule?
Hydrogen bonds and Hydrophobic forces
Which types of immunoglobulins can have both kappa and lambda light chains present?
IgG and IgM
What is the main difference between kappa and lambda light chains?
Amino acid sequences
Which type of peptide chain in an IgG molecule has a molecular weight of about 22,000?
Kappa (κ) chains
Learn about the discovery of antibodies and their role in the adaptive immune response. Explore the substance in the blood that neutralizes toxins produced by bacteria.
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