Podcast
Questions and Answers
What is the role of the substantia nigra pars compacta in the brain?
What is the role of the substantia nigra pars compacta in the brain?
- Activate the direct pathway
- Suppress the indirect pathway
- Inhibit the putamen and caudate
- Provide dopaminergic input to the putamen and caudate (correct)
Which specific neurons are lost in Parkinson's disease?
Which specific neurons are lost in Parkinson's disease?
- Dopaminergic neurons (correct)
- Serotonin neurons
- GABAergic neurons
- Cholinergic neurons
What happens to the direct pathway in Parkinson's disease?
What happens to the direct pathway in Parkinson's disease?
- Becomes less active (correct)
- Remains unaffected
- Switches to inhibitory mode
- Becomes more active
Which part of the brain is primarily affected by the loss of dopamine in Parkinson's disease?
Which part of the brain is primarily affected by the loss of dopamine in Parkinson's disease?
What results from the indirect pathway becoming more active in Parkinson's disease?
What results from the indirect pathway becoming more active in Parkinson's disease?
Which receptors respond differently to dopamine in Parkinson's disease?
Which receptors respond differently to dopamine in Parkinson's disease?
What key symptom of Parkinson's disease is a result of action selection suppression via the direct pathway?
What key symptom of Parkinson's disease is a result of action selection suppression via the direct pathway?
'Rigidity' as a symptom of Parkinson's disease is a consequence of:
'Rigidity' as a symptom of Parkinson's disease is a consequence of: