18 Questions
Which class of immunoglobulin is associated with the alpha heavychain?
IgA
Why should care be taken to avoid hemolysis during specimen preparation for serological tests?
Hemolysis interferes with the interpretation of test results.
Which of the following temperature ranges is recommended for storing serum if testing cannot be performed immediately?
2-8oC
In which biological activities related to immune response does immunoglobulin play a role?
Opsonization
What is the purpose of heating serum at 56oC for 30 minutes during specimen preparation?
To deactivate the antibodies
Which organization's regulations should be followed when transporting patient specimens to an immunology laboratory?
International Air Transport Association (IATA)
What is the function of C-Reactive Protein (CRP) and Antistreptolysin O (ASO) serology tests?
To assess streptococcal infection
In which blood sample would you typically find A and B antigens in RBCs?
Whole Blood sample in an EDTA tube
What does the Venereal Disease Research Laboratory (VDRL) test detect?
Syphilis infection
Which type of tube is used for collecting a sample to assess the presence of A antibodies and B antibodies in serum?
EDTA (Pink/Lavender)
What is the purpose of Whole Blood and Serum/Plasma samples collected in the lab?
To assess presence of antigens in RBCs
Why is a leak-proof container necessary for stool samples collected in the lab?
To prevent contamination of the sample
What is the main difference between antigens and immunogens?
Antigens are foreign substances that induce an immune response, while immunogens are substances capable of eliciting an immune response.
Which panel would be most appropriate to assess liver function in a patient?
Hepatic Function Panel
What is the main function of antibodies in the immune system?
Neutralize pathogens and toxins
Which of the following factors can lead to specimen rejection during testing?
Clot formation in the CBC tube
In serology, what is the primary focus when studying serum?
Qualitative detection or quantitative analysis of antibodies or antigens related to infection or disease
Which panel would be most useful in evaluating electrolyte levels in a patient?
Electrolyte Panel
Learn about the structure, production, and functions of immunoglobulins, including their role in antigen recognition, opsonization, and complement activation. Explore the major Ig classes and isotypes to understand their specific properties and functions.
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