Immunnoglobulins: Structure and Functions

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Questions and Answers

Which class of immunoglobulin is associated with the alpha heavychain?

  • IgA (correct)
  • IgM
  • IgE
  • IgG

Why should care be taken to avoid hemolysis during specimen preparation for serological tests?

  • Hemolysis helps in antigen recognition.
  • Hemolysis enhances the activity of immunoglobulins.
  • Hemolysis interferes with the interpretation of test results. (correct)
  • Hemolysis can increase the temperature of the sample.

Which of the following temperature ranges is recommended for storing serum if testing cannot be performed immediately?

  • -10oC
  • -70oC
  • 2-8oC (correct)
  • -30oC

In which biological activities related to immune response does immunoglobulin play a role?

<p>Opsonization (D)</p> Signup and view all the answers

What is the purpose of heating serum at 56oC for 30 minutes during specimen preparation?

<p>To deactivate the antibodies (A)</p> Signup and view all the answers

Which organization's regulations should be followed when transporting patient specimens to an immunology laboratory?

<p>International Air Transport Association (IATA) (C)</p> Signup and view all the answers

What is the function of C-Reactive Protein (CRP) and Antistreptolysin O (ASO) serology tests?

<p>To assess streptococcal infection (A)</p> Signup and view all the answers

In which blood sample would you typically find A and B antigens in RBCs?

<p>Whole Blood sample in an EDTA tube (B)</p> Signup and view all the answers

What does the Venereal Disease Research Laboratory (VDRL) test detect?

<p>Syphilis infection (D)</p> Signup and view all the answers

Which type of tube is used for collecting a sample to assess the presence of A antibodies and B antibodies in serum?

<p>EDTA (Pink/Lavender) (D)</p> Signup and view all the answers

What is the purpose of Whole Blood and Serum/Plasma samples collected in the lab?

<p>To assess presence of antigens in RBCs (C)</p> Signup and view all the answers

Why is a leak-proof container necessary for stool samples collected in the lab?

<p>To prevent contamination of the sample (A)</p> Signup and view all the answers

What is the main difference between antigens and immunogens?

<p>Antigens are foreign substances that induce an immune response, while immunogens are substances capable of eliciting an immune response. (A)</p> Signup and view all the answers

Which panel would be most appropriate to assess liver function in a patient?

<p>Hepatic Function Panel (B)</p> Signup and view all the answers

What is the main function of antibodies in the immune system?

<p>Neutralize pathogens and toxins (B)</p> Signup and view all the answers

Which of the following factors can lead to specimen rejection during testing?

<p>Clot formation in the CBC tube (A)</p> Signup and view all the answers

In serology, what is the primary focus when studying serum?

<p>Qualitative detection or quantitative analysis of antibodies or antigens related to infection or disease (D)</p> Signup and view all the answers

Which panel would be most useful in evaluating electrolyte levels in a patient?

<p>Electrolyte Panel (D)</p> Signup and view all the answers

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