Immunnoglobulins: Structure and Functions
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Questions and Answers

Which class of immunoglobulin is associated with the alpha heavychain?

  • IgA (correct)
  • IgM
  • IgE
  • IgG
  • Why should care be taken to avoid hemolysis during specimen preparation for serological tests?

  • Hemolysis helps in antigen recognition.
  • Hemolysis enhances the activity of immunoglobulins.
  • Hemolysis interferes with the interpretation of test results. (correct)
  • Hemolysis can increase the temperature of the sample.
  • Which of the following temperature ranges is recommended for storing serum if testing cannot be performed immediately?

  • -10oC
  • -70oC
  • 2-8oC (correct)
  • -30oC
  • In which biological activities related to immune response does immunoglobulin play a role?

    <p>Opsonization</p> Signup and view all the answers

    What is the purpose of heating serum at 56oC for 30 minutes during specimen preparation?

    <p>To deactivate the antibodies</p> Signup and view all the answers

    Which organization's regulations should be followed when transporting patient specimens to an immunology laboratory?

    <p>International Air Transport Association (IATA)</p> Signup and view all the answers

    What is the function of C-Reactive Protein (CRP) and Antistreptolysin O (ASO) serology tests?

    <p>To assess streptococcal infection</p> Signup and view all the answers

    In which blood sample would you typically find A and B antigens in RBCs?

    <p>Whole Blood sample in an EDTA tube</p> Signup and view all the answers

    What does the Venereal Disease Research Laboratory (VDRL) test detect?

    <p>Syphilis infection</p> Signup and view all the answers

    Which type of tube is used for collecting a sample to assess the presence of A antibodies and B antibodies in serum?

    <p>EDTA (Pink/Lavender)</p> Signup and view all the answers

    What is the purpose of Whole Blood and Serum/Plasma samples collected in the lab?

    <p>To assess presence of antigens in RBCs</p> Signup and view all the answers

    Why is a leak-proof container necessary for stool samples collected in the lab?

    <p>To prevent contamination of the sample</p> Signup and view all the answers

    What is the main difference between antigens and immunogens?

    <p>Antigens are foreign substances that induce an immune response, while immunogens are substances capable of eliciting an immune response.</p> Signup and view all the answers

    Which panel would be most appropriate to assess liver function in a patient?

    <p>Hepatic Function Panel</p> Signup and view all the answers

    What is the main function of antibodies in the immune system?

    <p>Neutralize pathogens and toxins</p> Signup and view all the answers

    Which of the following factors can lead to specimen rejection during testing?

    <p>Clot formation in the CBC tube</p> Signup and view all the answers

    In serology, what is the primary focus when studying serum?

    <p>Qualitative detection or quantitative analysis of antibodies or antigens related to infection or disease</p> Signup and view all the answers

    Which panel would be most useful in evaluating electrolyte levels in a patient?

    <p>Electrolyte Panel</p> Signup and view all the answers

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