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Questions and Answers
What is a common characteristic of lipids?
What is a common characteristic of lipids?
What is one of the functions of lipids in the body?
What is one of the functions of lipids in the body?
What is a lipid that is both water soluble and water insoluble called?
What is a lipid that is both water soluble and water insoluble called?
What is an example of a lipid derived from fatty acids?
What is an example of a lipid derived from fatty acids?
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What is the term for lipids that are fully water hating or insoluble in water?
What is the term for lipids that are fully water hating or insoluble in water?
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What is another function of lipids in the body?
What is another function of lipids in the body?
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What is a characteristic of the 'tail' of a fatty acid?
What is a characteristic of the 'tail' of a fatty acid?
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What is the reason for the kinks in the chain of unsaturated fatty acids?
What is the reason for the kinks in the chain of unsaturated fatty acids?
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What is the effect of cis double bonds on the fatty acid tail?
What is the effect of cis double bonds on the fatty acid tail?
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Why do longer fatty acid chains have higher melting points?
Why do longer fatty acid chains have higher melting points?
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What is unique about the rotation of the C=C double bond?
What is unique about the rotation of the C=C double bond?
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What is the purpose of counting the carbons starting from COOH in fatty acid nomenclature?
What is the purpose of counting the carbons starting from COOH in fatty acid nomenclature?
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What is a characteristic that lowers the melting point of a fatty acid?
What is a characteristic that lowers the melting point of a fatty acid?
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How can lipids be classified?
How can lipids be classified?
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What is the significance of the superscript delta (D) in fatty acid nomenclature?
What is the significance of the superscript delta (D) in fatty acid nomenclature?
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What is the backbone of glycerolipids?
What is the backbone of glycerolipids?
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What is the difference between mono- and poly-unsaturation in fatty acids?
What is the difference between mono- and poly-unsaturation in fatty acids?
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What is the result of structural isomerism in fatty acids?
What is the result of structural isomerism in fatty acids?
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What is a characteristic of triglycerides?
What is a characteristic of triglycerides?
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What is the format for writing the nomenclature of an unsaturated fatty acid?
What is the format for writing the nomenclature of an unsaturated fatty acid?
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What is a type of lipid that is composed of glycerol and fatty acids?
What is a type of lipid that is composed of glycerol and fatty acids?
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Why do lipids often fall into multiple categories?
Why do lipids often fall into multiple categories?
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What is the main role of triglycerides in the body?
What is the main role of triglycerides in the body?
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What is the result of esterification between glycerol and fatty acids?
What is the result of esterification between glycerol and fatty acids?
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What is the main difference between storage lipids and membrane lipids?
What is the main difference between storage lipids and membrane lipids?
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What is the main component of sphingolipids?
What is the main component of sphingolipids?
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What is the function of triglycerides in terms of buoyancy?
What is the function of triglycerides in terms of buoyancy?
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What type of bond links galactose to glycerol in galactolipids?
What type of bond links galactose to glycerol in galactolipids?
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What is the main role of phospholipids in the body?
What is the main role of phospholipids in the body?
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What is the main difference between galactolipids and phospholipids?
What is the main difference between galactolipids and phospholipids?
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Study Notes
Types of Biomolecules
- Nucleic acids (nucleotides)
- Proteins (amino acids)
- Carbohydrates (sugars)
- Lipids
Introduction to Lipids
- Lipids are a broad class of molecules that are insoluble in water
- Examples: waxes, oils, fats
- Lipids can be classified as:
- Hydrophobic (fully water-hating/insoluble in water)
- Amphipathic (water-soluble and water-insoluble groups on one molecule)
Functions of Lipids
- Energy storage
- Biomembranes
- Signaling
- Enzymatic co-factors
Fatty Acids
- Hydrophilic "head" and hydrophobic "tail"
- Typically 12 to 24 carbons, with an even number of carbons only
- Can be subdivided into:
- Mono- and poly-unsaturated fatty acids
- Structural isomerism in fatty acids (cis and trans configurations)
Fatty Acids Nomenclature
- Standard nomenclature: count the carbons starting from COOH, write the number down, followed by a colon
- Write the number of double bonds after the colon
- Write the first carbon of the double bond as a superscript to a delta (Δ)
- For unsaturated fatty acids, write down the cis/trans configuration
Melting Points
- The longer the chain, the higher the melting point
- Cis configuration double bonds lower the melting point
Classification of Lipids
- By synthetic pathway (e.g., steroids vs fatty acids)
- By function (e.g., source of energy, membrane components, messengers)
- By structure (e.g., simple, complex, derived)
- By chemical composition (e.g., phospholipids, glycolipids)
Glycerolipids
- Composed of glycerol and fatty acids
- Glycerol is a 3-carbon polyalcohol
- Triglycerides are a typical class of glycerolipids
Roles of Triglycerides
- Energy storage: energy-rich and can be packed up easily
- Buoyancy: low density and density changes with temperature
- Thermal insulation: fats do not conduct heat well, preventing heat loss
Phosphoglycerides
- Also known as glycerophospholipids
- Important in biomembranes
- Are a class of phospholipids
- Composed of glycerol, fatty acids, phosphate group, and polar head
Galactolipids
- Not phospholipids
- Galactose linked by a glycosidic bond to glycerol
- The fatty acids are typically linoleic acid
Sphingolipids
- Based on sphingosine
- Can be phospholipids
- Can be simple or complex
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