Unraveling the Mystery

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Questions and Answers

Which of the following is the main reason why mitochondrial DNA acquires mutations at a higher rate than nuclear DNA?

  • It is in close proximity to the electron transport chain. (correct)
  • It lacks DNA repair mechanisms.
  • It is exposed to high concentrations of free radicals.
  • It lacks protective histones.

What is the standard model of inheritance for mitochondrial DNA?

  • Biparental inheritance
  • Maternal inheritance (correct)
  • Paternal inheritance
  • Random inheritance

Which tissue showed evidence of a single, maternally derived mtDNA haplotype in a patient with mitochondrial myopathy?

  • Cardiac muscle
  • Skeletal muscle (correct)
  • Brain
  • Liver

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