Podcast
Play an AI-generated podcast conversation about this lesson
Questions and Answers
Which inhibitory molecules are targeted in tumor immunotherapy?
Which inhibitory molecules are targeted in tumor immunotherapy?
- CTLA-4 and PD-1 (correct)
- PD-L1 and CTLA-4
- PD-1 and TIM-3
- LAG-3 and TIM-3
What is the principle behind tumor immunotherapy?
What is the principle behind tumor immunotherapy?
- Engaging regulatory mechanisms to evade immune attack
- Suppressing immune responses to tumors
- Boosting host immune responses by blocking inhibitory signals for T cells (correct)
- Enhancing the efficacy of checkpoint blockade therapies
What is the response rate to checkpoint blockade therapies?
What is the response rate to checkpoint blockade therapies?
- Less than 10%
- 50% to 75%
- 25% to 40% (correct)
- More than 90%
Which type of tumors are the most likely to respond to checkpoint blockade therapy?
Which type of tumors are the most likely to respond to checkpoint blockade therapy?
Signup and view all the answers
What is the most common side effect associated with checkpoint blockade therapy?
What is the most common side effect associated with checkpoint blockade therapy?
Signup and view all the answers
What is the first approved example of combined checkpoint blockade therapy?
What is the first approved example of combined checkpoint blockade therapy?
Signup and view all the answers
What is the main role of inhibitory receptors targeted by checkpoint blockade therapy?
What is the main role of inhibitory receptors targeted by checkpoint blockade therapy?
Signup and view all the answers
