Podcast
Questions and Answers
Which of the following is true about the mitochondrial theory of ageing?
Which of the following is true about the mitochondrial theory of ageing?
- There is no evidence to support the mitochondrial theory of ageing.
- Somatic mutations in mtDNA result in the accumulation of reactive oxygen species. (correct)
- Somatic mutations in mtDNA do not affect cellular and tissue functions.
- Somatic mutations in mtDNA lead to an increase in mitochondrial function.
What did Vogelstein and colleagues find in their study on colorectal cancer cell lines?
What did Vogelstein and colleagues find in their study on colorectal cancer cell lines?
- All of the cell lines studied had mtDNA mutations.
- Only a few of the cell lines studied had mtDNA mutations. (correct)
- The study did not find any evidence of mtDNA mutations in colorectal cancer.
- No mtDNA mutations were present in any of the cell lines studied.
What is the relationship between mtDNA mutations and the development of tumours?
What is the relationship between mtDNA mutations and the development of tumours?
- mtDNA mutations only contribute to the detection of tumour recurrence.
- There is a direct link between the presence of mtDNA mutations and the development of tumours.
- There is no evidence to suggest that mtDNA mutations contribute to the development of tumours. (correct)
- mtDNA mutations only contribute to the detection of genotoxic damage.
What is the main consequence of the reactive oxygen species vicious cycle during ageing?
What is the main consequence of the reactive oxygen species vicious cycle during ageing?
What is the potential significance of mtDNA mutations in the detection of tumour recurrence?
What is the potential significance of mtDNA mutations in the detection of tumour recurrence?
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