Unlocking the Secrets of mtDNA Mutations

There is no evidence to support the mitochondrial theory of ageing.

Somatic mutations in mtDNA result in the accumulation of reactive oxygen species. (correct)

Somatic mutations in mtDNA do not affect cellular and tissue functions.

Somatic mutations in mtDNA lead to an increase in mitochondrial function.

All of the cell lines studied had mtDNA mutations.

Only a few of the cell lines studied had mtDNA mutations. (correct)

The study did not find any evidence of mtDNA mutations in colorectal cancer.

No mtDNA mutations were present in any of the cell lines studied.

mtDNA mutations only contribute to the detection of tumour recurrence.

There is a direct link between the presence of mtDNA mutations and the development of tumours.

There is no evidence to suggest that mtDNA mutations contribute to the development of tumours. (correct)

mtDNA mutations only contribute to the detection of genotoxic damage.

<p>Exponential increase in oxidative damage.</p> Signup and view all the answers

<p>mtDNA mutations can be used to detect the presence of tumours.</p> Signup and view all the answers