Understanding Tuberculosis: Causes and Spread Quiz
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Questions and Answers

Which group of individuals is more susceptible to developing TB disease?

  • Individuals with high cholesterol levels
  • Individuals with strong immune systems
  • Individuals who exercise regularly
  • Individuals with diabetes (correct)

What is the primary cause of tuberculosis?

  • Hepatitis B virus
  • _Escherichia coli_ bacteria
  • _Streptococcus pneumoniae_ bacteria
  • _Mycobacterium tuberculosis_ bacteria (correct)

Which genetic factor may be associated with increased susceptibility to TB?

  • Variations in HLA-DRA gene
  • Variations in HLA-DQA1 gene
  • Variations in HLA-DQB1 gene
  • Variations in HLA-DRB1 gene (correct)

How is tuberculosis predominantly spread?

<p>Through the air by infected individuals (B)</p> Signup and view all the answers

Why is prevention and early detection crucial for controlling tuberculosis?

<p>Because those with weakened immune systems are more vulnerable to developing active TB disease (D)</p> Signup and view all the answers

What is the bacterium responsible for causing tuberculosis?

<p><em>Mycobacterium tuberculosis</em> (C)</p> Signup and view all the answers

Which part of the body does tuberculosis primarily affect?

<p>Lungs (B)</p> Signup and view all the answers

What makes it difficult for antibiotics to penetrate the cell membrane of Mycobacterium tuberculosis?

<p>Presence of arabinogalactan (A)</p> Signup and view all the answers

How does tuberculosis primarily spread from person to person?

<p>Airborne droplets (A)</p> Signup and view all the answers

Which of the following conditions makes a person more susceptible to developing TB after exposure to the bacteria?

<p><em>Malnutrition</em> (C)</p> Signup and view all the answers

What characteristic of Mycobacterium tuberculosis contributes to its survival within the host?

<p><em>Unique cell wall structure</em> (B)</p> Signup and view all the answers

Study Notes

Understanding Tuberculosis and Its Causes

Tuberculosis, commonly referred to as TB, is a disease caused by mycobacteria, specifically Mycobacterium tuberculosis. It primarily affects the lungs, although it can also affect other parts of the body like the brain, kidneys, or spine. In this article, we will discuss the causes of tuberculosis and how it spreads.

Bacterial Structure and Resistance

The bacterium responsible for tuberculosis is Mycobacterium tuberculosis, which is a gram-positive aerobe. It has a unique cell wall structure that allows it to resist phagocytic digestion by immune cells, contributing to its ability to survive within the host. The cell wall of Mycobacterium tuberculosis contains a high content of mycolic acids, peptidoglycan, arabinogalactan, and lipoproteins. This complex composition makes it difficult for antibiotics to penetrate the cell membrane of the bacteria, leading to drug resistance.

Mode of Transmission

Tuberculosis spreads through tiny droplets released into the air when an infected person coughs, sneezes, or talks. People can also get infected by being around others who have active TB disease, mainly if they spend many hours with them in poorly ventilated spaces. While most people exposed to the bacteria do not develop TB, those with weakened immune systems are more likely to get sick.

Risks and Vulnerabilities

People with weakened immune systems, such as children, older adults, individuals living with HIV, and those with medical conditions like diabetes, malnutrition, or substance abuse disorders, are more susceptible to developing TB disease. Additionally, certain genetic factors may increase the risk of getting infected with Mycobacterium tuberculosis. Some studies suggest that variations in genes like HLA-DRB1 may be associated with increased susceptibility to TB.

In conclusion, tuberculosis is primarily caused by infection with Mycobacterium tuberculosis and is predominantly spread through the air by infected individuals. Those with weakened immune systems are more vulnerable to developing active TB disease, making prevention and early detection crucial for controlling this global health concern.

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Description

Test your knowledge on the causes and transmission of tuberculosis with this quiz. Explore topics like bacterial structures, drug resistance, modes of transmission, and vulnerable populations at risk of developing TB.

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