Understanding the Relationship between Na+ Content and Concentration in the Body

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11 Questions

What determines the Na+ concentration in the body?

Both the amount of Na+ and water present

What can cause an increased Na+ concentration with a normal Na+ content?

Decreased water content

What is the key element in proximal tubule reabsorption?

The Na+-K+-ATPase pump in the basolateral membrane

What is the approximate amount of Na+ reabsorbed by the renal tubules per day?

25,000 mEq/day

What percentage of filtered water, Na+, Cl-, and K+ is reabsorbed by the proximal tubule?

67%

What is reabsorbed by the proximal tubule in addition to water, Na+, Cl-, and K+?

Glucose and amino acids

How is Na+ reabsorbed in the first half of the proximal tubule?

Together with HCO−3 and other solutes

What mediates the disparity in Na+ reabsorption in the two halves of the proximal tubule?

Differences in the Na+ transport systems and tubular fluid composition

Which process results in sodium bicarbonate (NaHCO−3) reabsorption?

H+ excretion

What is one of the specific transport proteins that mediate Na+ entry into the cell across the apical membrane?

Na+ - K+ - ATPase pump

How is Na+ uptake into the cell coupled in the first half of the proximal tubule?

With H+ or organic solutes

This quiz explores the distinction between the Na+ content and concentration in the body, highlighting how changes in water volume can impact Na+ concentration regardless of Na+ content. Learn how an individual can have varying Na+ levels while maintaining different water volumes.

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