Understanding the Proteome
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Questions and Answers

What is the term for the entire set of proteins expressed by a genome?

  • Proteome (correct)
  • Transcriptome
  • Genotype
  • Genome

Why is the proteome larger than the number of genes in eukaryotes?

  • Because of the presence of non-coding RNA genes
  • Because of the varying metabolic activity of cells
  • Due to the process of alternative RNA splicing (correct)
  • As a result of cellular stress

What is the function of lysosomes in eukaryotic cells?

  • To form a network of membrane tubules
  • To digest proteins, lipids, nucleic acids, and carbohydrates (correct)
  • To transport material between membrane compartments
  • To synthesize proteins

What is the significance of the endoplasmic reticulum (ER) in eukaryotic cells?

<p>It forms a network of membrane tubules continuous with the nuclear membrane (A)</p> Signup and view all the answers

What is the effect of the small surface area to volume ratio in eukaryotic cells?

<p>It increases the total area of membrane (B)</p> Signup and view all the answers

What is the function of vesicles in eukaryotic cells?

<p>To transport material between membrane compartments (D)</p> Signup and view all the answers

Where are lipids synthesised in the cell?

<p>Smooth Endoplasmic Reticulum (SER) (D)</p> Signup and view all the answers

What is the function of a signal sequence in protein synthesis?

<p>To halt translation and direct the ribosome to dock with the ER (A)</p> Signup and view all the answers

What happens to proteins once they are in the ER?

<p>They are transported to the Golgi apparatus (D)</p> Signup and view all the answers

What is the major modification that occurs to proteins as they move through the Golgi apparatus?

<p>Glycosylation (C)</p> Signup and view all the answers

What is the fate of secreted proteins after they are packaged into vesicles in the Golgi apparatus?

<p>They are released out of the cell (D)</p> Signup and view all the answers

What is the type of bond that links amino acids together to form polypeptides?

<p>Peptide bond (C)</p> Signup and view all the answers

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