Understanding Psoriasis
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Questions and Answers

What is the key defect in psoriasis?

  • Increased collagen synthesis
  • Excessive production of melanin
  • Hyperproliferation of keratinocytes (correct)
  • Overproduction of sebum

    • Which genotype is associated with a 20 times higher risk of developing psoriasis?

  • HLA-B20
  • HLA-DQ2
  • HLA-DR4
  • HLA-Cw6 (correct)

    • What percentage of the general population is affected by psoriasis?

  • 8-10%
  • 3-5% (correct)
  • Less than 1%
  • 15-20%

    • What is the concordance rate for psoriasis in monozygotic twins compared to dizygotic twins?

    <p>70% vs. 20%</p> Signup and view all the answers

    Which age group is mostly involved in psoriasis?

    <p>15-45 years</p> Signup and view all the answers

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