M9: PPA
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Questions and Answers

PPA is a type of ___ dementia.

  • Vascular
  • Frontotemporal (correct)
  • Dementia with Lewy Bodies
  • AD
  • PPA is a neurodegenerative disorder characterized by ___.

  • transition stage or preclinical condition of intermediate symptoms between the cognitive changes associated with healthy aging and the salient cognitive impairments seen in Alzheimer’s disease or other dementias.
  • A gradual deterioration of speech and language abilities in the presence of relatively spared general cognitive abilities. (correct)
  • A rapid deterioration of speech and language abilities in the presence of relatively spared general cognitive abilities.
  • A gradual deterioration of speech and language abilities and general cognitive abilities.
  • To meet the PPA criteria, there needs to be a gradual onset of language problems, isolated in the initial stages of disease. What are the other criteria to meet the diagnosis of PPA?

    mpairment not explained by stroke, tumor, TBI, or other neurological or psychiatric conditions. No initial behavioral disturbances, prominent visuospatial or episodic memory deficits Impaired activities of daily living related to language deficit

    What are the 3 types of PPA?

    <p>Semantic Logopenic Nonfluent</p> Signup and view all the answers

    Match the neural bases for each variant of PPA

    <h1>SVPA = Temporal lobe atrophy LVPA = Temporoparietal atrophy NFVPPA = Frontoinsular atrophy</h1> Signup and view all the answers

    Single-word comprehension deficits and picture-naming deficits are core clinical features of this variant.

    <p>Semantic</p> Signup and view all the answers

    Apraxia of speech and agrammatism are core clinical features of this variant.

    <p>Nonfluent</p> Signup and view all the answers

    Phrase and sentence repetition deficit and difficulty with single-word retrieval in spontaneous speech and picture naming are core clinical features of this variant.

    <p>Logopenic</p> Signup and view all the answers

    As this variant progresses, patients may develop a movement disorder, dysphagia, progressively unintelligible and agrammatic speech, and mutism.

    <p>Nonfluent</p> Signup and view all the answers

    With SVPPA, atrophy spreads throughout the semantic network eventually affecting the frontal and parietal lobes. What are 3 other features that may develop?

    <p>Progressively empty speech Behavioral symptoms Worsening dysexecutive symptoms</p> Signup and view all the answers

    What features develop as LVPPA progresses?

    <p>Jargon like aphasic production Comprehension deficits emerge, especially for long, complex utterances Episodic memory impairment</p> Signup and view all the answers

    Repetition is intact with the logopenic variant.

    <p>False</p> Signup and view all the answers

    When assessing PPA, standard aphasia batteries and classifications may be used.

    <p>False</p> Signup and view all the answers

    What extralinguistic cognitive domains should be assessed?

    <p>General cognitive function Visuospatial processing and visual memory Emotional processing</p> Signup and view all the answers

    Individuals with this variant have poor grammar in written and spoken language. Therefore, they will perform poorly on subtests assessing grammatical processing.

    <p>Nonfluent</p> Signup and view all the answers

    Individuals with this variant will have difficulty with naming subtests and perform poorly on auditory comprehension subtests.

    <p>Semantic</p> Signup and view all the answers

    Individuals with this variant will have difficulty with naming subtests and impaired repetition

    <p>Logopenic</p> Signup and view all the answers

    On picture description tasks, individuals with this variant will exhibit fluent speech with high frequency nouns, pronouns, and verbs and a normal speech rate.

    <p>Semantic</p> Signup and view all the answers

    On picture description tasks, individuals with this variant will exhibit an intermediate speech rate, syntactic errors, lexical retrieval difficulties, and phonemic paraphasias.

    <p>Logopenic</p> Signup and view all the answers

    On picture description tasks, individuals with this variant exhibit agrammatic and slow speech with frequent speech distortions.

    <p>Nonfluent</p> Signup and view all the answers

    Residual semantic knowledge is important for treatment items and retrieval of episodic memories and personally relevant treatment items leads to improved outcomes.

    <p>True</p> Signup and view all the answers

    In the treatment of lexical retrieval for all variants of PPA, research on the utilization of the paired presentation of picture and spoken and/or written word form has shown gains for trained items, with little generalization to untrained items or contexts.

    <p>True</p> Signup and view all the answers

    Research on the utilization of cueing hierarchies, including semantic feature analysis, and phonemic and orthographic cues has shown gains for trained items, generalization to untrained items, and maintenance up to 1-year

    <p>True</p> Signup and view all the answers

    The use of AAC has shown promise with individuals with PPA. What is a critical component of using AAC in this population?

    <p>It is important to begin training before significant cognitive deficits emerge.</p> Signup and view all the answers

    Video implemented script training in aphasia (VISTA) has been used to thrift NFVPPA. Research shows minimaal gains for trained scripts, with no improvement in speech intelligibility observed for untrained tasks, and no generalization.

    <p>False</p> Signup and view all the answers

    Individuals with NFVPPA and LVPA have ___ object knowledge skills.

    <p>Perserved</p> Signup and view all the answers

    With LVPPA, we see impaired phonological processing due to ___ atrophy, greater in the language-dominant hemisphere.

    <p>Temporoparietal</p> Signup and view all the answers

    With NFVPPA, we see impaired ___ ___ and/or apraxia of speech due to frontoinsular atrophy, greater in the language-dominant hemisphere.

    <p>Grammatical processing</p> Signup and view all the answers

    Mixed PPA is relatively common.

    <p>False</p> Signup and view all the answers

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