12 Questions
What is the primary cause of neuronal death in the Substantia Niagra leading to Parkinson's Disease?
Mutation of the Parkin gene
How is Parkinson's Disease treated?
Dopaminergic drugs to compensate for deficient dopamine secretion
What effect do dopaminergic drugs used in Parkinson's treatment have?
Generalized with a lot of side effects and tolerance
What coincides with the relatively new emergence of Parkinson's Disease, suggesting a possible cause?
The industrial age and high exposure to pesticides and toxins
What is the function of the sub-thalamic nucleus post-gene replacement in Parkinson's disease?
Inhibits the Globus Pallidus, leading to stimulation of movement
What is a concern associated with gene replacement for Parkinson's disease?
Use of viral vectors can be unpredictable
What is a potential long-term cure for Parkinson's disease involving pluripotent cells?
Stem cell treatment
What is a characteristic of Huntington's disease?
Associated with constant movement and brain degeneration
What is a characteristic of stem cells derived from adults for treatment?
Can be reverted into pluripotent state and converted into any cell type
What is a characteristic of deep-brain stimulation for Parkinson's disease?
Involves implantation of electrodes to alter circuit functions
What is a key difference between Huntington's disease and Parkinson's disease?
Parkinson's is stuck in the OFF mode, while Huntington's is stuck in the ON mode.
What is a concern associated with surgical ablation for Parkinson's disease?
It involves surgically-induced brain damage with high risk.
Test your knowledge about Parkinson's Disease with this quiz covering its symptoms, causes, and impact on individuals. Learn more about the relation between neuronal death in the Substantia Niagra and Parkinson's Disease.
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