1.2. SOCIAL DETERMINANTS OF HEALTH
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Questions and Answers

What is the primary goal of the Dollar Street activity as described?

  • To calculate the exact income of families worldwide using a specific formula.
  • To provide a detailed analysis of healthcare systems in different countries.
  • To compare families globally based on their income and visualize their living conditions. (correct)
  • To create a database of family names and addresses for research purposes.

How should each group use the Dollar Street tool, according to the instructions?

  • Each group should focus on a single country and thoroughly investigate its economic indicators.
  • Each group should analyze the entire dataset and prepare a comprehensive report.
  • Each group should compare all four entries in a single row of Dollar Street, based on their assigned row number. (correct)
  • Each group should randomly select families from different rows and create a comparative analysis.

What is the initial setting recommended for exploring the Dollar Street page effectively?

  • Sorting entries alphabetically by country name.
  • Filtering data based on specific family sizes.
  • Configuring the view to 'Families in the World by Income'. (correct)
  • Setting the view to display 'Healthcare Access by Region'.

When drawing up a table to compare the entries, what kind of information can usually be derived from the Dollar Street content?

<p>Country, monthly income, observations from the content, life expectancy, maternal mortality, expected years of schooling and HDI Value. (D)</p> Signup and view all the answers

If a group is assigned 'Row 5' of Dollar Street, what action should they take?

<p>They should compare all four entries in Row 5, focusing on their incomes and living conditions. (C)</p> Signup and view all the answers

According to the information presented, how do structural and political processes primarily contribute to health inequities?

<p>By influencing the everyday living conditions of individuals and populations. (A)</p> Signup and view all the answers

Which factor is identified as a fundamental driver of social inequities in health?

<p>Unequal distribution of power, money, and resources. (B)</p> Signup and view all the answers

What is the most accurate interpretation of the 'social gradient in health'?

<p>Health status tends to improve with increasing economic status. (B)</p> Signup and view all the answers

Based on the provided data, what is the correlation between a country's monthly income observation and its Human Development Index (HDI) value?

<p>There is a positive correlation; as monthly income increases, the HDI value tends to increase. (D)</p> Signup and view all the answers

What is the most encompassing approach an expert should take to address health inequities, based on the content?

<p>Addressing the social determinants of health at multiple levels. (C)</p> Signup and view all the answers

Which of the following statements can be best inferred from the data regarding the relationship between life expectancy and maternal mortality?

<p>Countries with higher life expectancy tend to have lower maternal mortality rates. (D)</p> Signup and view all the answers

Considering the data, which factor appears to have the LEAST direct correlation to the Human Development Index (HDI)?

<p>Type of sandals worn (A)</p> Signup and view all the answers

Social determinants of health can be best described as:

<p>Social and economic factors that influence health and well-being. (B)</p> Signup and view all the answers

The social determinants of health are factors that:

<p>Shape the conditions in which people live, work, and grow. (B)</p> Signup and view all the answers

Assuming Ukraine's expected years of schooling is 15, which of the following is the MOST reasonable estimate for Ukraine's HDI value, based on the data trends?

<p>0.840 (B)</p> Signup and view all the answers

What is the primary difference between health equality and health equity?

<p>Health equality focuses on providing the same resources to everyone, while health equity recognizes that different people need different resources. (D)</p> Signup and view all the answers

In what way can social factors external to an individual impact their health?

<p>They can either promote well-being or confer disease risk depending on the conditions. (C)</p> Signup and view all the answers

A hypothetical country, 'Zandia', has a life expectancy of 68 years, maternal mortality of 60 per 100,000 live births, and expected years of schooling of 12. Which country from the provided data is Zandia MOST similar to in terms of these development indicators?

<p>Philippines (A)</p> Signup and view all the answers

According to the World Health Organization, what is the definition of 'health equity'?

<p>The absence of systematic disparities in health that are avoidable and unjust. (D)</p> Signup and view all the answers

What do social gradients in health typically demonstrate?

<p>A direct correlation between socioeconomic status and health outcomes. (B)</p> Signup and view all the answers

What is the relationship between social determinants of health and health inequities?

<p>Social determinants are the primary mechanism through which health inequities are manifested. (C)</p> Signup and view all the answers

Based on the figures provided regarding maternal mortality and under-5 mortality rates, which statement accurately reflects a key finding?

<p>There's an inverse relationship between household income and under-5 mortality rates. (C)</p> Signup and view all the answers

What critical aspect does health equity take into account when addressing population health?

<p>Acknowledging and addressing the unique social, economic, and environmental factors affecting different groups. (A)</p> Signup and view all the answers

If a public health intervention aims to improve health equality, which strategy would be LEAST effective?

<p>Tailoring interventions to address the specific needs of marginalized communities. (D)</p> Signup and view all the answers

Which scenario exemplifies a situation where focusing solely on health equality would NOT lead to health equity?

<p>Providing the same dose of medication to every patient regardless of their weight or metabolism. (A)</p> Signup and view all the answers

What would be most effective in reducing the social gradient observed in under-5 mortality rates?

<p>Investing in early childhood development programs within low-income communities. (A)</p> Signup and view all the answers

Which of the following best describes the primary purpose of using frameworks in the context of social determinants of health?

<p>To visually represent health determinants, their relative importance, and their interactions to improve understanding and approaches to improve health outcomes. (B)</p> Signup and view all the answers

A healthcare organization aims to address high rates of diabetes in a low-income community. Using a social determinants of health framework, which initial step would be MOST effective?

<p>Analyzing the various social, economic, and environmental factors contributing to diabetes in that community. (D)</p> Signup and view all the answers

When designing a framework to illustrate social determinants of health, what is the most important consideration?

<p>The framework should accurately represent the relationships and relative importance of different determinants. (A)</p> Signup and view all the answers

Which of the following is NOT a core characteristic of a good framework for analyzing social determinants of health?

<p>It provides emotional support for affected individuals. (A)</p> Signup and view all the answers

A public health initiative aims to reduce smoking rates. How would a social determinants of health framework inform their strategy?

<p>By addressing factors such as targeted advertising, stress, peer influence, and access to cessation programs. (A)</p> Signup and view all the answers

A rural community has limited access to fresh produce, contributing to poor nutrition and health outcomes. Using a social determinants of health framework, what intervention would address the root cause of this issue?

<p>Partnering with local farmers to establish a community-supported agriculture (CSA) program and farmers market. (B)</p> Signup and view all the answers

In a city with significant health disparities, city planners notice that certain neighborhoods lack safe places to exercise. They want to use a social determinants of health framework to understand why this inequity exists. Which question aligns best with this framework?

<p>What historical policies and current zoning regulations have contributed to the unequal distribution of resources and infrastructure for physical activity? (A)</p> Signup and view all the answers

Researchers are using a framework to study infant mortality rates in different socioeconomic groups. They observe that lower income groups have higher rates. Which follow-up investigation best utilizes the framework's principles?

<p>Analyzing differences in access to prenatal care, nutrition, housing quality, and exposure to environmental hazards across socioeconomic groups. (B)</p> Signup and view all the answers

The Dahlgren and Whitehead framework is applied to a case study. Which of the following best describes the primary purpose of using this framework?

<p>To analyze the multiple layers of influence, including individual, social, and environmental factors, that affect health outcomes in the case study. (B)</p> Signup and view all the answers

In the context of social determinants of health, what is the significance of Wilkinson and Marmot's statement: '...the common causes of the ill health that affects populations are environmental?'

<p>It emphasizes the predominant role of environmental factors over individual genetic susceptibilities in influencing the overall health of populations. (A)</p> Signup and view all the answers

When applying the Dahlgren and Whitehead framework to understand tuberculosis (TB) as Lönnroth et al. (2009) did, which factors would be analyzed?

<p>The interplay of individual lifestyle factors, social and community networks, and broader socioeconomic and environmental conditions contributing to TB incidence. (B)</p> Signup and view all the answers

When analyzing Type II diabetes using social determinants of health frameworks, like Hill et al. (2013), what broader factors beyond individual choices are considered?

<p>Access to healthy food options, cultural influences on diet, and socioeconomic status affecting lifestyle. (C)</p> Signup and view all the answers

How might social determinants of health frameworks, such as that used by Decker et al. (2018) regarding violence, be applied to reduce incidents of violence in a community?

<p>By addressing underlying issues such as poverty, lack of education, and community disorganization that contribute to violent behavior. (A)</p> Signup and view all the answers

A public health initiative aims to reduce the incidence of childhood obesity in a low-income community. According to the social determinants of health, which intervention would be MOST effective?

<p>Partnering with local grocery stores to increase the availability and affordability of fresh produce, while also creating safe spaces for physical activity. (A)</p> Signup and view all the answers

A rural community has limited access to healthcare services, leading to poor health outcomes. Which approach aligns BEST with addressing this issue through a social determinants of health perspective?

<p>Establishing a mobile health clinic that provides primary care services, health education, and connects residents to social support programs. (A)</p> Signup and view all the answers

How should we interpret that genetics could make someone more susceptible to a disease but environmental factors are the 'common causes' of ill health?

<p>That environmental factors often have a greater impact on disease, and a wider reach across populations, than genetics alone.. (A)</p> Signup and view all the answers

How does lifestyle medicine primarily aim to address chronic diseases?

<p>By using evidence-based behavioral interventions to prevent, treat, and manage the disease. (A)</p> Signup and view all the answers

What broader impact does lifestyle medicine advocate for, beyond individual health improvements?

<p>The creation of a healthier society and environment in conjunction with medical interventions. (D)</p> Signup and view all the answers

Which of the following best describes the integrated approach of lifestyle medicine?

<p>Integrates environmental, behavioral, medical, and motivational strategies for managing health problems. (D)</p> Signup and view all the answers

What is the potential environmental co-benefit of reducing meat consumption, as suggested?

<p>It may benefit the environment alongside improvements in cardiovascular health. (A)</p> Signup and view all the answers

In the context of overall well-being, what does the passage emphasize as a key component of prevention and care?

<p>Focusing patients' attention on the health of the human body, diet, and causes of disease. (A)</p> Signup and view all the answers

Based on the information provided, which approach would likely be MOST effective in addressing lifestyle-related health problems?

<p>Integrating environmental stewardship with healthy lifestyle choices and medical support. (B)</p> Signup and view all the answers

How can combining environmental stewardship and healthy lifestyles contribute to overall wellness?

<p>It offers co-benefits that improve both personal wellness and the health of the environment. (B)</p> Signup and view all the answers

Considering the principles of lifestyle medicine, which action would LEAST likely be recommended for managing a patient's Type 2 diabetes?

<p>Prescribing medication as the primary and only intervention. (D)</p> Signup and view all the answers

How does the concept of 'Environmental Mindfulness' relate to an individual's response to planetary health challenges?

<p>It promotes awareness of personal reactions to ecological changes, potentially fostering proactive environmental behaviors. (B)</p> Signup and view all the answers

Which of the following actions BEST exemplifies an individual applying their 'personal power' to improve planetary health?

<p>Making conscious, eco-friendly lifestyle choices and advocating for environmental protection policies. (C)</p> Signup and view all the answers

How does understanding the interconnectedness between daily habits and environmental impact primarily contribute to improving environmental wellness?

<p>It enables individuals to make informed decisions that minimize their ecological footprint and promote sustainability. (B)</p> Signup and view all the answers

What is the MOST comprehensive way to promote the co-benefits of ecosystem welfare for human health?

<p>Advocating for policies that prioritize both environmental conservation and public health initiatives in conjunction. (A)</p> Signup and view all the answers

An individual feels overwhelmed and anxious due to constant news about climate change. What approach best aligns with 'Environmental Mindfulness' to address these feelings?

<p>Acknowledging the feelings, reflecting on their causes, and identifying constructive actions to take. (C)</p> Signup and view all the answers

Which initiative demonstrates integrating environmental stewardship with a healthy lifestyle to yield 'co-benefits?'

<p>A community switching to a more sustainable diet to minimize food waste and greenhouse gas emissions. (D)</p> Signup and view all the answers

Referring to the interconnectedness with health, wellbeing and nature, what is the MOST significant outcome of becoming more environmentally aware?

<p>Recognizing how one's actions affect the environment and implementing changes for a harmonious existence. (C)</p> Signup and view all the answers

How does environmental wellness, which involves promoting interaction with nature, contribute to individual well-being?

<p>It reduces stress and promotes a balanced lifestyle through connecting with nature. (C)</p> Signup and view all the answers

What is the primary impact of global ecological drivers on daily life, according to the material?

<p>Heightened challenges to mental health and overall wellness. (B)</p> Signup and view all the answers

What is the role that awareness plays in achieving wellness, according to the material?

<p>It is an active process that helps people make informed choices towards a successful existence. (A)</p> Signup and view all the answers

In what way does personal power relate to environmental protection and planetary health?

<p>Personal power is the individual's ability to create balance, resilience, and a self-leading lifestyle that protects the environment. (B)</p> Signup and view all the answers

What is the MOST direct outcome of enhancing one's environmental awareness?

<p>Greater understanding of how daily habits impact the environment and the Planet. (A)</p> Signup and view all the answers

How does environmental mindfulness relate to one's response to climate hazards and ecological changes?

<p>It enhances awareness of one's thoughts and reactions to environmental challenges. (A)</p> Signup and view all the answers

What is the relationship between ecosystem welfare and human health?

<p>Promoting the welfare and well-being of the ecosystem leads to co-benefits for human health. (A)</p> Signup and view all the answers

A city is implementing new urban planning strategies. Which approach aligns best with the principles of planetary 'Health and Wellness'?

<p>Integrating green spaces, promoting sustainable transportation, and ensuring access to local, healthy food options. (D)</p> Signup and view all the answers

An individual wants to improve their environmental wellness. Which action represents the MOST direct approach to achieving this?

<p>Spending more time in nature and adopting environmentally conscious practices. (D)</p> Signup and view all the answers

What is the primary focus of lifestyle medicine in the context of managing chronic diseases?

<p>Utilizing evidence-based behavioral interventions to prevent, treat, and manage diseases. (C)</p> Signup and view all the answers

How does lifestyle medicine integrate environmental considerations into its approach to healthcare?

<p>By advocating for healthier societies and environments as a key component of treatment and prevention. (D)</p> Signup and view all the answers

What key elements are combined within Lifestyle Medicine when addressing health problems?

<p>Environmental, behavioral, medical, and motivational principles. (B)</p> Signup and view all the answers

How might reducing meat consumption contribute to both individual and environmental well-being?

<p>It offers co-benefits by improving cardiovascular health and reducing environmental impact. (A)</p> Signup and view all the answers

According to Thomas Edison's quote, what should be the future direction of medical practice?

<p>Educating patients about caring for their bodies, diet, and disease prevention. (C)</p> Signup and view all the answers

What is a significant relationship between health, wellness, and environmental stewardship?

<p>Healthy communities and lifestyles create co-benefits for both personal wellness and environmental preservation. (A)</p> Signup and view all the answers

In addressing lifestyle-related health problems, what makes lifestyle medicine distinct?

<p>It strategically combines environmental, behavioral, medical, and motivational elements. (B)</p> Signup and view all the answers

Given the references provided, what can be inferred about the scope of factors influencing health and wellness?

<p>The influences on health and wellness extend beyond individual choices, encompassing psychosocial problems, environmental factors, and differences in meanings of health. (A)</p> Signup and view all the answers

Based on the data, how does the prevalence of Klebsiella pneumoniae (K.pneumo) differ between Southern Africa and the provided 'Middle Africa' data?

<p>K.pneumo is present in Southern Africa but data is unavailable for Middle Africa. (B)</p> Signup and view all the answers

What is a significant finding regarding the outcomes of infections caused by carbapenem-resistant organisms, based on the information?

<p>Infections caused by carbapenem-resistant organisms are associated with high case fatality rates. (B)</p> Signup and view all the answers

What factor is identified as a predictor of death in the studies discussed?

<p>Infection with organisms resistant to cephalosporins. (C)</p> Signup and view all the answers

What is the economic projection of the global cost resulting from antimicrobial resistance (AMR), according to the Review on Antimicrobial Resistance?

<p>USD 100 trillion (A)</p> Signup and view all the answers

Considering the available data, which geographical area is likely to experience the greatest impact from antimicrobial resistance (AMR)?

<p>Sub-Saharan Africa (SSA) (C)</p> Signup and view all the answers

According to the information, what statement accurately describes the number of studies conducted on CRE (Carbapenem-resistant Enterobacterales) in Southern Africa?

<p>There are 11 studies from one country. (B)</p> Signup and view all the answers

Based on the geographical distribution of CRE species in Africa, which inference is accurate?

<p>There is geographical variation in the distribution of CRE species across African countries. (B)</p> Signup and view all the answers

Considering the data provided, which of the following statements is most likely true? Consider the relationship between E. coli and K. pneumo in Southern Africa.

<p>Southern Africa has a lower prevalence of <em>E. coli</em> compared to <em>K. pneumo</em>. (D)</p> Signup and view all the answers

What distinguishes acquired antimicrobial resistance from intrinsic resistance in microbes?

<p>Acquired resistance develops over time, whereas intrinsic resistance is always present. (B)</p> Signup and view all the answers

Which mechanism enables the MOST efficient spread of antimicrobial resistance genes between bacteria?

<p>Transfer of resistance genes via plasmids. (A)</p> Signup and view all the answers

What is a key difference between integrons and transposons in the context of spreading antimicrobial resistance?

<p>Integrons shuttle and carry resistance genes, while transposons sometimes are transferable. (B)</p> Signup and view all the answers

How does antimicrobial resistance directly undermine the effectiveness of clinical treatments?

<p>By enabling microbes to survive exposure to antimicrobial agents. (D)</p> Signup and view all the answers

Which of the following resistance mechanisms involves the direct uptake of genetic material from the surrounding environment?

<p>Uptake of ‘Naked DNA’ (D)</p> Signup and view all the answers

Considering the information regarding antimicrobial resistance (AMR) in East Africa, what can be concluded about the prevalence of resistance?

<p>A significant percentage of bloodstream infections are caused by bacteria resistant to third-generation cephalosporins. (D)</p> Signup and view all the answers

Based on the data presented, what is a potential implication of high rates of antimicrobial resistance in bloodstream infections?

<p>Higher mortality rates and prolonged hospital stays. (B)</p> Signup and view all the answers

What is the primary significance of understanding whether antimicrobial resistance is an attribute of the microbe rather than the host?

<p>It guides strategies for preventing transmission and development in the microbial population. (A)</p> Signup and view all the answers

What is the primary implication of the high percentage of beta-lactam and beta-lactamase inhibitor (BLI) combinations in the antibiotic clinical pipeline?

<p>The focus is primarily on incremental improvements to existing antibiotic classes rather than developing fundamentally new ones. (A)</p> Signup and view all the answers

How does antibiotic use create selective pressure that leads to increased antimicrobial resistance?

<p>By eliminating susceptible bacteria, allowing resistant strains to thrive due to reduced competition. (D)</p> Signup and view all the answers

Considering the global trend in antibiotic consumption between 2000 and 2010, and the concurrent rise in antibiotic resistance, which strategy would be MOST effective in mitigating this issue?

<p>Implementing comprehensive antibiotic stewardship programs in both hospitals and communities, coupled with improved surveillance. (B)</p> Signup and view all the answers

What does the decreasing 'Ratio of Access:Watch antibiotics' in low-middle income countries from 2000 to 2015 indicate?

<p>An increasing reliance on 'Watch' antibiotics relative to 'Access' antibiotics, potentially indicating overuse and increased resistance. (D)</p> Signup and view all the answers

Given the limited surveillance of hospital-acquired infections (HAIs) and under-resourced infection control in South Africa, how might this affect the spread of antibiotic-resistant organisms?

<p>It allows for the unchecked spread of resistant organisms within healthcare settings, exacerbating the problem. (C)</p> Signup and view all the answers

Considering the information provided, how do global antibiotic consumption patterns relate to the development of antibiotic resistance?

<p>Increased antibiotic consumption globally, especially of broad-spectrum antibiotics, contributes to the selection and spread of antibiotic resistance. (C)</p> Signup and view all the answers

What is the significance of 'selective pressure' in the context of antibiotic resistance?

<p>Selective pressure describes the process by which antibiotics eliminate susceptible bacteria, giving resistant bacteria a survival advantage. (A)</p> Signup and view all the answers

Based on the data regarding antibiotic resistance in South Africa, what is the MOST pressing concern for clinicians?

<p>The high rates of cephalosporin resistance in Klebsiella and carbapenem resistance in Acinetobacter, coupled with limited new antibiotic options. (D)</p> Signup and view all the answers

Which of the following agricultural practices is MOST likely to contribute to increased antimicrobial resistance?

<p>Using low doses of antibiotics in animal feed over extended periods to promote growth. (B)</p> Signup and view all the answers

What is the PRIMARY concern regarding the use of shared antimicrobials in both human and animal health?

<p>Antimicrobial resistance developed in animals can potentially transfer to human pathogens. (B)</p> Signup and view all the answers

A community is experiencing a high rate of antibiotic use for both humans and animals. Which intervention would MOST effectively address the problem of antimicrobial resistance from a 'One Health' perspective?

<p>Implement coordinated strategies to reduce antibiotic use in both human and animal populations, alongside environmental monitoring. (A)</p> Signup and view all the answers

A veterinary clinic is observing increased resistance to first-line antimicrobials in common animal pathogens. Which action would be MOST effective for promoting responsible antimicrobial use in this setting?

<p>Implementing antimicrobial stewardship programs that emphasize diagnostics and targeted treatment. (D)</p> Signup and view all the answers

Based on the information provided, which factor poses the GREATEST risk for the transmission of antimicrobial-resistant bacteria from animals to humans?

<p>The use of antimicrobials for growth promotion and metaphylaxis in animal agriculture. (B)</p> Signup and view all the answers

What is the MOST effective way to minimize selective pressure outside of human medicine that leads to AMR?

<p>Reduce the usage of antimicrobials in agriculture and companion animals. (D)</p> Signup and view all the answers

In South Africa, tetracyclines and beta-lactams are commonly used in both animal and human health. What is the MOST likely consequence of this practice?

<p>Emergence of resistance to these antimicrobials in both animal and human pathogens. (A)</p> Signup and view all the answers

A public health agency aims to address antimicrobial resistance in a specific community. Which strategy would be the MOST comprehensive and effective?

<p>Implementing a 'One Health' approach that addresses antimicrobial use in humans, animals, agriculture, and the environment. (C)</p> Signup and view all the answers

If a child under two years of age requires a rabies vaccination, which injection site is recommended?

<p>Anterolateral thigh (A)</p> Signup and view all the answers

How many vials of rabies vaccine constitute a single dose for both adults and children?

<p>One vial (B)</p> Signup and view all the answers

Following a potential rabies exposure, what is the standard schedule for administering the four-dose vaccination course?

<p>Days 0, 3, 7, and any day between days 14 and 28 (D)</p> Signup and view all the answers

In adults, into which muscle should the rabies vaccine be injected?

<p>Deltoid muscle (D)</p> Signup and view all the answers

Besides vaccination what other patient management steps should be taken?

<p>Wound Care (A)</p> Signup and view all the answers

Based on the provided information, which activities pose the HIGHEST risk of exposure to Crimean-Congo Hemorrhagic Fever (CCHF)?

<p>Undertaking outdoor activities such as hunting and hiking. (D)</p> Signup and view all the answers

A patient presents with a sudden onset of fever, severe myalgia, and photophobia. Which of the following actions would be MOST appropriate, based solely on the material provided?

<p>Immediately isolate the patient and consider CCHF in the differential diagnosis. (C)</p> Signup and view all the answers

If a public health official aims to reduce the incidence of CCHF in the Northern Cape and Free State Provinces, which intervention would MOST directly address the primary risk factor?

<p>Distributing insect repellent and promoting tick bite prevention measures. (C)</p> Signup and view all the answers

A clinician in South Africa observes a patient with epistaxis, haematemesis, and ecchymoses on day 4 of their illness, preceded by fever and myalgia. Which of the following diagnostic tests should be PRIORITIZED, based on the information?

<p>Complete blood count to assess platelet levels and coagulation profile. (A)</p> Signup and view all the answers

Considering the epidemiology of CCHF in South Africa, what is the MOST accurate inference regarding the geographical distribution of the disease?

<p>The majority of CCHF cases originate from the Northern Cape and Free State Provinces. (C)</p> Signup and view all the answers

What is a key epidemiological characteristic of rabies, based on the information?

<p>A significant proportion of rabies deaths occur in children, particularly in Asia and Africa. (B)</p> Signup and view all the answers

Considering rabies virus diversity, which statement is MOST accurate?

<p>Several rabies-related viruses have been identified in different geographical areas. (C)</p> Signup and view all the answers

What is the significance of post-exposure prophylaxis (PEP) in the context of rabies?

<p>PEP is administered to approximately 10 million people globally each year after suspected exposure. (D)</p> Signup and view all the answers

How does South Africa's rabies mortality rate compare to global figures?

<p>South Africa experiences a relatively low number of rabies deaths annually compared to the global burden. (A)</p> Signup and view all the answers

What is a common characteristic among the rabies-related viruses mentioned?

<p>They exhibit specific geographical distributions rather than being universally present. (D)</p> Signup and view all the answers

Considering the information provided, what factor contributes to the high global impact of rabies?

<p>The high mortality rate combined with widespread occurrence, particularly in specific regions and age groups. (A)</p> Signup and view all the answers

How might the structural characteristics of the rabies virus influence its transmission?

<p>The lipid solvent sensitivity will reduce the effectiveness of soap and disinfectants (B)</p> Signup and view all the answers

Given the data on the global distribution of different rabies-related viruses, what could be a challenge in rabies control efforts?

<p>The genetic diversity of rabies viruses and their specific geographical distributions would complicate vaccine development and control strategies. (A)</p> Signup and view all the answers

If a new lyssavirus is discovered in bats in a region not previously known to harbor such viruses, what would be the MOST important initial step?

<p>Conducting comprehensive surveillance to determine the virus's prevalence, host range, and genetic characteristics. (A)</p> Signup and view all the answers

How might future rabies prevention programs benefit from knowing which animal species are reservoirs for different rabies-related viruses?

<p>Effective, species-specific vaccination programs can be rolled out. (D)</p> Signup and view all the answers

What is the typical timeframe for recovery to begin in patients who survive Crimean-Congo Hemorrhagic Fever (CCHF)?

<p>Around 10 days after the onset of symptoms. (B)</p> Signup and view all the answers

Based on the information given, if a person resided in an area known for animal-tick interactions and develops CCHF-like symptoms, how should this factor into the diagnosis?

<p>It should be considered as supportive evidence, particularly if coupled with other exposure risks. (A)</p> Signup and view all the answers

Considering the different routes of exposure, which scenario poses the highest risk of CCHF transmission, based solely on the 'Incubation < 1 week' column?

<p>Being bitten by a tick or squashing it barehanded. (A)</p> Signup and view all the answers

If a healthcare worker sustains a needle stick injury while treating a confirmed CCHF patient, what is the likelihood of the incubation period being longer than one week?

<p>Less likely, based on the data provided. (C)</p> Signup and view all the answers

Given the mortality rate of CCHF in South Africa, what is the approximate number of deaths expected from the 200 cases reported since 1981?

<p>Between 40 and 60 deaths. (A)</p> Signup and view all the answers

A farmer recalls squashing a tick with their bare hands approximately 9 days prior to the onset of symptoms that are consistent with CCHF. How should the timing of this event be considered in the clinical assessment?

<p>It is within the possible incubation period, supporting suspicion for CCHF. (D)</p> Signup and view all the answers

If two individuals have contact with CCHF, one through a tick bite and another through exposure to contaminated animal blood, what is a key difference in how their cases might present, based on incubation?

<p>The tick bite victim is more likely to have a shorter incubation period compared to the individual exposed to animal blood (B)</p> Signup and view all the answers

In a region reporting a surge in CCHF cases, which intervention would be MOST effective in reducing transmission related to 'direct contact with fresh blood or other tissues from farm and wild animals'?

<p>Implementing stricter biosecurity measures in farms and slaughterhouses. (B)</p> Signup and view all the answers

What should be prioritized when managing a patient with Crimean-Congo Hemorrhagic Fever (CCHF) to improve their immediate outcome?

<p>Providing comprehensive hemodynamic support, including fluid balance, electrolyte correction and oxygenation. (D)</p> Signup and view all the answers

Why is prompt differential diagnosis crucial in suspected cases of Crimean-Congo Hemorrhagic Fever (CCHF)?

<p>To rule out other diseases with similar symptoms, guiding appropriate and timely management. (C)</p> Signup and view all the answers

In the context of Crimean-Congo Hemorrhagic Fever (CCHF) prevention, why is public education emphasized alongside vector control?

<p>Public education empowers individuals to take preventive measures, reducing tick exposure and promoting early reporting of symptoms. (C)</p> Signup and view all the answers

What is the 'One Health' approach, as it relates to Crimean-Congo Hemorrhagic Fever (CCHF), designed to achieve?

<p>Integrating human, animal, and environmental health considerations to prevent disease transmission. (A)</p> Signup and view all the answers

Given that no vaccine is currently available in South Africa for Crimean-Congo Hemorrhagic Fever (CCHF), what is the MOST effective strategy for personal protection against the disease?

<p>Consistent use of tick repellents containing DEET or permethrin to prevent tick bites. (A)</p> Signup and view all the answers

In managing a patient with Crimean-Congo Hemorrhagic Fever (CCHF), when would blood and platelet transfusions be MOST indicated?

<p>To correct thrombocytopenia and manage bleeding disorders. (A)</p> Signup and view all the answers

What immediate step should a healthcare provider take upon suspecting a case of Crimean-Congo Hemorrhagic Fever (CCHF) in South Africa?

<p>Report the case to the appropriate public health authorities due to its notifiable status. (A)</p> Signup and view all the answers

What precautions are MOST important for healthcare workers to implement when handling specimens from a patient suspected of having Crimean-Congo Hemorrhagic Fever (CCHF)?

<p>Using universal precautions and ensuring proper packing of specimens in special containers. (A)</p> Signup and view all the answers

What is the recommended approach for administering Rabies Immunoglobulin (RIG) when a patient has multiple wounds?

<p>Divide the calculated RIG dose equally and infiltrate all wounds after diluting with equal parts saline. (D)</p> Signup and view all the answers

What is the maximum time frame after rabies vaccine administration beyond which Rabies Immunoglobulin (RIG) is generally considered less effective?

<p>Not beyond 7 days after vaccination (A)</p> Signup and view all the answers

In the context of Viral Hemorrhagic Fevers (VHFs), what poses the greatest risk for human-to-human transmission?

<p>Close contact involving contaminated fluids and fomites, especially in nosocomial settings (A)</p> Signup and view all the answers

What is the role of arthropods in maintaining and transmitting arboviruses in nature?

<p>Arthropods transmit the virus through transovarial transmission and between susceptible vertebrate hosts. (B)</p> Signup and view all the answers

Which factor related to the virus itself MOST influences the transmission and circulation of arboviruses?

<p>The virus strains' infectiousness for the vector and their ability to produce effective viremia (B)</p> Signup and view all the answers

What aspect of reservoir hosts MOST influences arbovirus circulation within a given environment?

<p>The reservoir host's attractiveness to vectors and its capacity to develop effective viremia (D)</p> Signup and view all the answers

How might the presence of predators and parasites affect the transmission and circulation of arboviruses?

<p>By altering the behavior and health of reservoir hosts, potentially influencing interaction rates with vectors. (B)</p> Signup and view all the answers

What is the primary source of information for the South African Rabies Prevention Guidelines (2021)?

<p>NICD website (D)</p> Signup and view all the answers

Considering the factors influencing arbovirus dynamics, if a particular virus strain demonstrates low infectiousness to its arthropod vector, what is the most likely consequence?

<p>Reduced efficiency of viral transmission within the ecosystem. (C)</p> Signup and view all the answers

In a scenario where a reservoir host population becomes less attractive to arthropod vectors due to environmental changes, what would be the anticipated impact on arbovirus transmission?

<p>Arbovirus transmission would likely decrease due to reduced vector-host interactions. (A)</p> Signup and view all the answers

What is the most critical component of care to prevent human-to-human transmission of VHF?

<p>Implement strict barrier nursing and infection control precautions. (A)</p> Signup and view all the answers

What is the dose of equine-derived Rabies Immunoglobulin (RIG) product to be administered?

<p>40 IU/kg (D)</p> Signup and view all the answers

What is the most accurate description of the ecological cycles involved in zoonotic infections related to Viral Hemorrhagic Fevers (VHFs)?

<p>Infections maintained in nature involving reservoir hosts and vectors. (B)</p> Signup and view all the answers

In a region experiencing an outbreak of an arbovirus, what measure addressing the reservoir hosts would MOST effectively reduce transmission to humans?

<p>Implementing measures to reduce the interaction between vectors and reservoir hosts. (B)</p> Signup and view all the answers

If a new Viral Hemorrhagic Fever (VHF) emerges that is NOT arthropod-borne, what would be the most effective strategy to prevent its spread?

<p>Implementing strict protocols to prevent contact with contaminated bodily fluids and fomites. (A)</p> Signup and view all the answers

Flashcards

Determinants of Health

Factors that influence health outcomes.

Health equity

A state where everyone has a fair and just opportunity to be as healthy as possible, removing obstacles like poverty and discrimination.

Health equality

Equality means each individual or group of people is given the same resources or opportunities.

Health inequalities

The systematic differences in health status between different groups, often linked to social or economic factors.

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WHO definition of health equity

The World Health Organization (WHO) defines health equity as the absence of unfair, avoidable or remediable differences among groups of people.

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Social gradient in health

The graded relationship between socioeconomic status and health outcomes.

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Under-5 mortality rate

Mortality rate of children under five years old per 1,000 live births, often used as an indicator of overall population health and well-being.

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Maternal Mortality Rate

The proportion of mothers who died during pregnancy. Its is measured across countries.

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Social Determinants of Health (SDOH)

Factors related to the conditions in which people live, work, and grow that affect their health and well-being.

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Fundamental Drivers of Health Inequities

Inequities in power, money, and resources that shape the conditions of daily life and lead to social inequities in health.

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Visual Representation of Social Gradient

A visual representation of how health improves with increasing economic status.

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Characteristics of Social Determinants

Factors external to individuals that shape living conditions and can promote well-being or disease risk.

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Social Determinants of Health - Broad Definition

The range of interacting factors that shape health and well-being.

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Why SDOH Matter?

To address health inequities by acting on factors like income, education, and access to healthcare.

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Dollar Street

A website that visually compares families from different countries based on their income.

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Families in the World by Income

The primary filter used on Dollar Street to organize and compare families.

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Comparative Table

A way to systematically examine and contrast data points across different families on Dollar Street.

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Life Expectancy

The expected length of life for an individual in a specific country.

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Maternal Mortality

The death rate of mothers during childbirth per 100,000 live births.

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Human Development Index (HDI)

A composite index measuring average achievement in key dimensions of human development: life expectancy, education, and standard of living.

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Expected Years of Schooling

The number of years a child of school entrance age is expected to spend in school.

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Kenya HDI Value

HDI value for Kenya

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What is a framework?

A set of ideas or facts providing support for something, a format supporting a theory, or a structure guiding development.

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Why use frameworks?

Frameworks visually represent health determinants, show their importance, and illustrate their interactions.

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Social determinants frameworks

Using social determinants of health frameworks promotes understanding of factors affecting health and suggests ways to improve health outcomes.

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Interaction of Factors

Frameworks illustrate how different factors interact to influence health outcomes.

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Framework Visuals

Visual representation of the factors that influence health.

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Frameworks for Problem Solving

A logical approach to identify problems and decide on actions.

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Complex Issue Frameworks

A conceptual structure used to address complex issues.

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Dahlgren and Whitehead framework

A framework for understanding how different levels of factors influence health.

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Environmental Influence on Health

Factors impacting health aren't just genetic; environment plays a key role.

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SDOH Frameworks & Tuberculosis

Social determinants of health applied to understand and address the root causes of tuberculosis.

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SDOH Frameworks & Type II Diabetes

Social determinants of health applied when analyzing contributing factors and potential interventions for Type II diabetes.

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SDOH Frameworks & Violence

Social determinants of health frameworks used to study the complex web of factors which lead to violence.

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Interrelated Health Factors

A set of factors (social, environmental, and economic) are related to each other to compound the effects on health.

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Environmental Determinants of Population Health

The common causes of ill health that affect populations are often environmental.

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Environment > Genes?

Even if genetic risks exist, the environment heavily impacts health.

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Ill-Planet Effect on Health

Impact of global ecological factors on daily life, leading to mental health challenges.

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Wellness Definition

A conscious, evolving process of achieving full potential, including awareness of others' well-being.

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Health and Wellness Power

Balance, resilience, and self-leading lifestyle choices to protect the environment and the Planet.

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Environmental Wellness

Promoting interaction with nature and having a strong environmental consciousness.

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Environmental Awareness

Becoming aware of the interconnection between health, well-being, and nature, realizing daily habits' impact.

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Environmentally Conscious Practices

Practices you adopt to improve your relationship with the environment.

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Environmental Mindfulness

Awareness of reactions to climate hazards, natural disasters and hazards due to ecological drivers changes.

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Health Dependence

Health depends on lifestyle choices and external environmental factors.

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Co-benefits

Benefits that occur simultaneously for both personal health and the environment through aligned actions.

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Lifestyle Medicine

A medical approach using evidence-based behavior interventions to prevent, treat, and manage diseases, especially chronic ones.

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Chronic Diseases

Diseases that are strongly linked to lifestyle factors such as diet, exercise, and habits.

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Reduce Meat Consumption

Reducing or eliminating meat consumption can improve heart health and conserve natural resources.

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Lifestyle Medicine as First-Line Treatment

Clinical practice guidelines recommend lifestyle medicine as a primary treatment for non-communicable diseases.

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Holistic Management

Managing health problems related to lifestyle through environmental, behavioral, medical, and motivational techniques.

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Environmental Stewardship

Environmental stewardship involves responsible use and protection of the natural environment through conservation and sustainable practices.

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Wellness and Environmental Stewardship

Combining healthy personal choices with actions that benefit the environment and community leads to better wellness and a healthier planet.

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Ill-Planet Impact

The result of global ecological drivers on daily life and affects mental health.

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Planetary Health Concerns

Climate change, air pollution, and loss of biodiversity.

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Wellness

An evolving, self-directed process to realize one's full potential and being aware of others.

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Health Improvement

Improving health depends on lifestyle choices and environmental aspects.

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Individual Power

Balance, resilience, and self-leading lifestyle choices to protect the environment and the Planet.

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Environmental Wellness Definition

Promoting interaction with and having a strong consciousness of nature.

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CRE

Carbapenem-resistant Enterobacterales are bacteria resistant to carbapenem antibiotics.

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Antimicrobial Resistance (AMR)

Antimicrobial resistance (AMR) occurs when microbes evolve to withstand drugs.

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K. pneumoniae

Klebsiella pneumoniae is a type of bacteria. In this context, it is referring to a strain that is resistant to antibiotics.

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E. coli

Escherichia coli is a type of bacteria. In this context, it is referring to a strain that is resistant to antibiotics.

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K.pneumoniae in Southern Africa

Southern Africa showed a K.pneumoniae presence of 63.6%.

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AMR in Sub-Saharan Africa

The SSA region is likely to be heavily impacted by AMR.

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Economic impact of AMR

AMR could cost the global economy USD 100 trillion.

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Pneumo Case Fatality Rate

A high case fatality rate (>60%) was reported in studies regarding pneumo.

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Increasing Antibiotic Resistance

Becoming more common, making infections harder to treat.

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Poor HAI Surveillance

Inadequate tracking of infections acquired while in the care of a healthcare provider.

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Poor Antibiotic Use

Using antibiotics when they aren't needed, or not using the right ones.

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Limited Antibiotic Pipeline

There are not many new antibiotics in development to fight resistant bacteria.

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Antibiotic Use Drives Resistance

Using antimicrobials causes resistance to them.

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Antibiotics and genetic changes

Antibiotics don't directly cause changes in organisms.

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Antibiotics & Selective Advantage

Antibiotics give resistant bacteria a better chance to thrive.

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Increasing Antibiotic Use

The rate of antibiotic consumption is going up worldwide.

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Plasmids (in AMR)

DNA elements like plasmids that can transfer resistance genes between bacteria.

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Acquired Resistance

Resistance that develops over time in a microbe, rather than being naturally present.

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Transposons (in AMR)

DNA sequences that can move from one location to another within a cell's DNA, spreading resistance genes.

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Integrons

Genetic elements that can capture and mobilize genes, including resistance genes, within bacteria.

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"Naked DNA" uptake

The uptake of free DNA from the environment by bacteria, which can include resistance genes.

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Bacteriophages

Viruses that infect bacteria and can transfer genetic material, including resistance genes, between them.

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Chromosomal Mutation (AMR)

Spontaneous changes in a bacteria's DNA after replication that leads to antimicrobial resistance.

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AMR Scope

Antimicrobial resistance extending beyond human health care.

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Therapeutic Antimicrobial Use

Use of antimicrobials to treat a specific infection in an individual.

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Prophylactic Antimicrobial Use (Individual)

Use of antimicrobials to prevent infection in high-risk individuals or settings.

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Prophylactic Antimicrobial Use (Community)

Use of antimicrobials to prevent outbreaks in a community under specific circumstances.

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Metaphylaxis

Using antimicrobials to treat entire animal groups, often in agriculture.

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Antimicrobials for Growth Promotion

Adding low doses of antimicrobials to animal feed over time.

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Antibiotic Use (Animals vs. Humans)

Animals use more antibiotics than human health.

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Shared Antimicrobials

Agents used for animals are also used for humans.

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Rhabdoviridae

A family of viruses that includes rabies virus.

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Rabies Virus Shape

Rabies is caused by a bullet-shaped virus.

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Rabies Virus Sensitivity

Rabies virus is sensitive to pH changes and lipid solvents.

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Global Rabies Deaths

More that 59,000 people die from rabies each year.

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Rabies geographic distribution

Most rabies cases occur in Asia and Africa.

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Rabies Deaths in South Africa

Rabies leads to about 15-20 deaths per year.

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"Street" Rabies.

A type of rabies found worldwide.

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Lagos Bat Virus

A rabies related virus found in Central Africa, Ghana, Kenya, Nigeria, Senegal and South Africa

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Mokola Virus

A rabies related virus found in Africa

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Duvenhage Virus

A rabies related virus found in Kenya, South Africa, and Zimbabwe

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Extent of Exposure

Assess the depth and breadth of the wound or area of contact with a potentially infectious source.

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Category of Exposure

Determine the risk level based on the type of exposure (e.g., needle stick, bite, scratch).

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Wound Care

Proper cleaning and dressing of wounds to prevent infection.

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Four-Dose Vaccination Course

A series of four injections given on days 0, 3, 7, and between days 14-28 for post-exposure prophylaxis.

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IM Injection Site

Administer intramuscularly in the deltoid for adults, or anterolateral thigh for children under 2 years.

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CCHF

Crimean-Congo Hemorrhagic Fever, a disease endemic to Africa, Europe, and the Middle East.

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CCHF in South Africa

South Africa has reported human CCHF cases annually since 1981.

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CCHF Hotspots in SA

Most CCHF cases in South Africa originate from the Northern Cape and Free State Provinces.

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Early CCHF Symptoms

Common early symptoms include fever, rigors, headache, and photophobia.

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Late-Stage CCHF Signs

Later symptoms include petechiae, ecchymoses, haematemesis and epistaxis.

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CCHF Diagnosis: PCR

Crimean-Congo Hemorrhagic Fever diagnosis via PCR on blood samples.

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CCHF: Antibody testing

Detects IgG and IgM to identify past or present CCHF infection.

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CCHF: Virus Isolation

Isolating the virus from a blood sample.

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CCHF: Haemodynamic support

Fluid management and electrolyte correction.

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CCHF: Transfusions

Blood and platelet transfusions.

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CCHF: Ribavirin

Antiviral medication used in CCHF treatment.

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CCHF Prevention: Repellents

Uses repellents to prevent tick bites.

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CCHF Prevention - IPC

Using standard safety measures to prevent spread.

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CCHF Incubation Period

Time between exposure to CCHF virus and symptom onset; usually less than 1 week but can be slightly longer.

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CCHF Recovery Onset

Survival recovery period for CCHF patients begins around this time.

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CCHF Mortality Rate

The estimated mortality rate for Crimean-Congo Hemorrhagic Fever.

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Annual CCHF Cases in SA

Typical number of CCHF cases reported annually in South Africa.

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CCHF Exposure: Tick/Animal Contact

Route of CCHF virus exposure; often involves contact with infected ticks or animals without protection.

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CCHF Exposure: Animal Tissue

Route of CCHF virus exposure; handling fresh blood or tissues from infected animals.

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CCHF Exposure: Needle Stick

Route of CCHF virus exposure; accidental injury with contaminated needles or contact with bodily fluids of CCHF patients.

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CCHF Risk Area

A potential source of infection; could involve contact with animals or ticks.

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RIG Dose

Dosage of Rabies Immunoglobulin is 20 IU/kg (human) or 40 IU/kg (equine).

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RIG Timing

RIG should be administered ASAP (not beyond 7 days post-vaccine)

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Arbovirus

Viral infections transmitted via arthropods.

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Zoonotic Infections

Infections transmitted from animals to humans.

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Spillover Event

Transfer of a pathogen from its animal reservoir to a human.

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Biological Transmission

Transmission between living organisms through blood feeding arthropods.

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Transovarial Transmission

Transmission from parent arthropod to offspring.

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Contaminated Bodily Fluids

Bodily secretions from a person that can transmit human pathogens.

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Fomites

Surfaces or objects that can transmit infectious agents.

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Nosocomial

Hospital setting

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Viral Haemorrhagic Fever (VHF)

Fever caused by viral infection, characterized by bleeding.

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Reservoir Host

Animal (or environment) in which a pathogen persists.

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Viraemia

The concentration of virus circulating in an organism’s bloodstream.

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Virus Infectiousness

The capacity of different virus isolates to infect the host.

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Host Attractiveness

Attraction of a host to a vector.

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Study Notes

Health Equity vs. Equality

  • Health equality is distinct from health equity.

Social Gradients in Health

  • There is an inverse relationship between maternal education and mortality during pregnancy
  • There is an inverse relationship between under-5 mortality and household income

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