Understanding Digoxin's Therapeutic Index

Plasma drug concentrations that produce toxicity are very close to the minimum concentration at which a beneficial effect occurs. (correct)

Plasma drug concentrations are extremely variable from animal to animal.

Plasma drug concentrations that produce toxicity are very low.

Plasma drug concentrations required to achieve a beneficial effect are very high.

Decreased appetite, anorexia, diarrhea, and vomiting (correct)

Increased coughing and difficulty breathing

Increased urination and increased water consumption

Wobbly gait, fainting (syncope), and disorientation

Hypernatremia

Hypokalemia (correct)

Hyperkalemia

Hypochloremia

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