Understanding Constipation
41 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is NOT a cause of constipation?

  • Results of taking other medication (opioids)
  • Frequent bowel movements (correct)
  • Inappropriate diet
  • Lack of physical activity

Which type of laxative absorbs fluid from the lumen and increases the consistency of the stool?

  • Bulk-forming laxatives (correct)
  • Osmotic laxatives
  • Stimulant laxatives
  • All of the above

Which natural resource is commonly used as an osmotic laxative?

  • Manna (correct)
  • Linum usitatissimum (lini semen/linseed)
  • Plantago psyllium (psyllii semen/psyllium)
  • Fraxinus ornus

Which of the following is a pharmacodynamic effect of sennosides?

<p>Increased leakiness of tight junctions (A)</p> Signup and view all the answers

Which of the following is a pharmacokinetic property of sennosides?

<p>Presence in blood as glucuronides and sulphates (C)</p> Signup and view all the answers

Which of the following is a side effect of long-term use of stimulant laxatives?

<p>Pseudomelanosis coli (C)</p> Signup and view all the answers

Which natural resource is commonly used as a stimulant laxative?

<p>Cassia Senna (D)</p> Signup and view all the answers

Why is the use of Senna contraindicated during pregnancy?

<p>It may pose a genotoxic risk (A)</p> Signup and view all the answers

Which type of laxative is not digested or absorbed in the GI tract?

<p>Bulk-forming laxatives (B)</p> Signup and view all the answers

Which natural resource is commonly used as an osmotic laxative?

<p>Manna (A)</p> Signup and view all the answers

Which of the following is the most common discoloration of urine that may occur during treatment with sennosides?

<p>Yellow (C)</p> Signup and view all the answers

What is the main mechanism of action of sennosides as a laxative?

<p>Stimulating the motility of the large intestine (C)</p> Signup and view all the answers

Which of the following is a potential side effect of long-term use of stimulant laxatives?

<p>Pseudomelanosis coli (B)</p> Signup and view all the answers

What is the recommended duration of use for Senna as a laxative?

<p>Up to 1 week (D)</p> Signup and view all the answers

Which of the following is a potential side effect of long-term use of sennosides as a laxative?

<p>Yellow discoloration of urine (A)</p> Signup and view all the answers

What is the main mechanism of action of sennosides as a laxative?

<p>Stimulation of the motility of the large intestine (C)</p> Signup and view all the answers

Which hydroxyanthracene derivative has been shown to be genotoxic in vitro and in vivo?

<p>Aloe emodin (C)</p> Signup and view all the answers

Which of the following is a potential adverse effect of long-term use of Senna as a laxative?

<p>Blackening of the colon (B)</p> Signup and view all the answers

Which of the following is a potential interaction with Senna as a laxative?

<p>Decreased effectiveness of cardiac glycosides (C)</p> Signup and view all the answers

What is the recommended posology for Senna as a laxative?

<p>Once daily at night (C)</p> Signup and view all the answers

Which of the following is a cause of constipation?

<p>Inadequate physical activity (D)</p> Signup and view all the answers

Which chemical constituents are responsible for the effect of stimulant laxatives?

<p>Antaquinones (D)</p> Signup and view all the answers

Which of the following is a natural resource commonly used as a bulk-forming laxative?

<p>Linum usitatissimum (A)</p> Signup and view all the answers

Which type of laxative absorbs fluid from the lumen and increases the consistency of the stool?

<p>Bulk-forming laxatives (A)</p> Signup and view all the answers

Which chemical constituents are responsible for the effect of stimulant laxatives?

<p>Anthranols (B)</p> Signup and view all the answers

Which of the following is a potential adverse effect of long-term use of Senna as a laxative?

<p>Yellow or red-brown discoloration of urine (C)</p> Signup and view all the answers

Which hydroxyanthracene derivative has been shown to be genotoxic in vitro and in vivo?

<p>Danthron (D)</p> Signup and view all the answers

Which type of laxative is not absorbed in the upper gut and is converted into an active metabolite by bacteria in the large intestine?

<p>Contact laxative (A)</p> Signup and view all the answers

Which of the following is a potential adverse effect of long-term use of Senna as a laxative?

<p>Pseudomelanosis coli (A)</p> Signup and view all the answers

Which of the following is a contraindication for the use of Senna as a laxative?

<p>Appendicitis (A)</p> Signup and view all the answers

What is the main mechanism of action of sennosides as a laxative?

<p>Increasing peristalsis of the colon (A)</p> Signup and view all the answers

Which of the following is a potential interaction with Senna as a laxative?

<p>Diuretics (B)</p> Signup and view all the answers

Which of the following is a potential adverse effect of long-term use of Senna as a laxative?

<p>Increased risk of colon cancer (C)</p> Signup and view all the answers

What is the main mechanism of action of sennosides as a laxative?

<p>Stimulation of large intestine motility (B)</p> Signup and view all the answers

Which hydroxyanthracene derivative has been shown to be genotoxic in vitro and in vivo?

<p>Aloe emodin (D)</p> Signup and view all the answers

Which of the following is a natural resource commonly used as a bulk-forming laxative?

<p>A) Linum usitatissimum (lini semen/linseed) (C)</p> Signup and view all the answers

Which type of laxative absorbs fluid from the lumen and increases the consistency of the stool?

<p>A) Bulk-forming laxatives (A)</p> Signup and view all the answers

Which chemical constituents are responsible for the effect of stimulant laxatives?

<p>D) All of the above (D)</p> Signup and view all the answers

Which of the following is a potential adverse effect of long-term use of Senna as a laxative?

<p>Hypersensitivity reactions (A)</p> Signup and view all the answers

What is the recommended duration of use for Senna as a laxative?

<p>Not to be used for more than 1 week (D)</p> Signup and view all the answers

Why is the use of Senna contraindicated during pregnancy?

<p>It may have genotoxic risk (B)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser