Understanding Cells: Theory and Types

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Questions and Answers

The presence of a distinct nuclear lamina, composed of lamin-associated proteins and lamins, is a universal characteristic of all cell types, irrespective of their differentiation status or origin.

False (B)

The cell theory, as originally formulated by Schleiden and Schwann, posits that all organisms are composed of cells, and each cell arises de novo, independent of pre-existing cells.

False (B)

The exclusive presence of N-acetylmuramic acid in cell walls is definitive evidence that the cell is exclusively a bacterial cell.

False (B)

Epithelial tissues manifest identical structural polarity across all subtypes, characterized by a uniformly positioned apical membrane and basolateral domain irrespective of function or location.

<p>False (B)</p> Signup and view all the answers

In the context of cell biology, the glycocalyx—a carbohydrate-rich layer on the cell surface—is exclusively composed of glycosaminoglycans covalently linked to integral membrane proteins.

<p>False (B)</p> Signup and view all the answers

Lipid rafts, characterized by their dynamic assembly enforced by their compositional heterogeneity, are enriched with sphingolipids, cholesterol, and GPI-anchored proteins but devoid of transmembrane proteins to maintain their structural integrity within the plasma membrane.

<p>False (B)</p> Signup and view all the answers

The rough endoplasmic reticulum's (RER) exclusive function is protein synthesis and folding, rendering it incapable of participating in lipid metabolism or the detoxification of hydrophobic compounds.

<p>False (B)</p> Signup and view all the answers

The translocon, a protein-conducting channel in the ER membrane, exhibits unidirectional transport, solely facilitating the movement of polypeptide chains from the cytosol into the ER lumen.

<p>False (B)</p> Signup and view all the answers

All eukaryotic cells invariably possess a single, centrally located Golgi apparatus that functions as a unified processing and sorting station for newly synthesized proteins and lipids.

<p>False (B)</p> Signup and view all the answers

The constitutive secretory pathway is exclusively responsible for the regulated release of specialized cellular products, such as hormones or neurotransmitters, in response to specific extracellular signals.

<p>False (B)</p> Signup and view all the answers

Lysosomal hydrolases, optimally functional at a neutral pH, are indiscriminately targeted to lysosomes irrespective of their glycosylation status or mannose-6-phosphate (M6P) tag.

<p>False (B)</p> Signup and view all the answers

Autophagy, a catabolic process, exclusively targets fully assembled and functional organelles for degradation, ensuring the preservation of damaged or dysfunctional cellular components.

<p>False (B)</p> Signup and view all the answers

Mitochondria, characterized by their exclusive dependence on the nuclear genome, completely lack the ability to encode any of their essential protein components, relying solely on import from the cytoplasm.

<p>False (B)</p> Signup and view all the answers

The primary function of peroxisomes is the synthesis of ribosomal RNA (rRNA), which is then exported to the cytoplasm for ribosome assembly.

<p>False (B)</p> Signup and view all the answers

Microtubules exhibit dynamic instability due to the exclusive hydrolysis of GTP bound to β-tubulin at the minus end, leading to depolymerization only from the centrosome.

<p>False (B)</p> Signup and view all the answers

Actin filaments, exclusively dependent on ATP hydrolysis for their polymerization, are completely incapable of undergoing reversible assembly or disassembly in response to cellular signals.

<p>False (B)</p> Signup and view all the answers

Muscle cells are exclusively striated due to the precise arrangement of actin and myosin filaments into sarcomeres, a characteristic absent in all non-muscle cells.

<p>False (B)</p> Signup and view all the answers

The only role of the nuclear pore complex (NPC) is to passively permit diffusion of all molecules smaller than 40 kDa, while actively transporting selective macromolecules in a bidirectional manner.

<p>False (B)</p> Signup and view all the answers

The nucleolus, the site of ribosome biogenesis, exclusively transcribes ribosomal RNA (rRNA) genes but is completely devoid of any involvement in ribosome assembly or quality control.

<p>False (B)</p> Signup and view all the answers

The main function of epithelial cells is sensation and transportation of nerve impulses.

<p>False (B)</p> Signup and view all the answers

The plasma membrane, comprised of a uniform lipid composition, maintains consistent fluidity across all cellular regions, ensuring equal permeability to all molecules regardless of size or charge.

<p>False (B)</p> Signup and view all the answers

The primary function of muscular cells is responsible for sensation and transportation of nerve impulses.

<p>False (B)</p> Signup and view all the answers

Neurons (nerve cells) are considered modified muscular cells in internal human organs.

<p>False (B)</p> Signup and view all the answers

Smooth muscle cells are a type of epithelial cell with brush boarders, microvilli, secretory cells and basket cells.

<p>False (B)</p> Signup and view all the answers

The structural and functional unit of living organisms is the tissue.

<p>False (B)</p> Signup and view all the answers

Smooth muscles are striated and involuntary.

<p>False (B)</p> Signup and view all the answers

Smooth muscles are found in external organs as stomach and small intestine.

<p>False (B)</p> Signup and view all the answers

Sensory cells covert the stimuli into nerve impulses for the brain to process.

<p>True (A)</p> Signup and view all the answers

One example of sensory cells is photoreceptors in skin.

<p>False (B)</p> Signup and view all the answers

Neurons contain groups of Nissl's bodies (group of Golgi apparatus and chromosomes), which produce proteins of neurons.

<p>False (B)</p> Signup and view all the answers

Flashcards

What is a cell?

The functional and structural unit of living organisms.

Cell Structure

A unit surrounded by a plasma membrane, containing cytoplasm and organelles like mitochondria and ribosomes.

Cell Theory

All living things are made of cells, the cell is the basic unit of life, and cells come from pre-existing cells.

Epithelial cells

Covers and protects surfaces; can be modified for secretion.

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Muscular cells

Responsible for movement.

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Nervous cells

For sensation and nerve impulse transportation.

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Cell modification

Structural or functional change that helps a cell perform specific tasks.

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Brush borders and microvilli

Increase surface area on epithelial cells for absorption.

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Basket cells

Modified epithelial cells that turn into contractile cells for squeezing glands.

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Sensory cells

Specialized cells that detect stimuli like light, sound, and touch.

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Study Notes

  • A cell is the functional and structural unit of living organisms.
  • A cell is surrounded by a plasma membrane, also known as the plasma lemma.
  • A cell contains cytoplasm and organelles, such as mitochondria, lysosomes, endoplasmic reticulum, and ribosomes.

Cell Theory

  • All organisms are composed of cells.
  • Cells are the structural and functional unit of life.
  • Cells arise from pre-existing cells.
  • Cells vary in shape and size.

Human Cell Types

  • Epithelial cells cover and protect the outer and inner layers of the body, including the skin, internal organs, and small intestine.
  • Epithelial cells can be modified to perform specific functions, such as secretion.
  • Epithelial cell types include squamous, cuboidal, and columnar cells.
  • Muscular cells are responsible for movement of the body.
  • Muscular cell types include cardiac muscles (in the heart), skeletal muscles, and smooth muscles.
  • Nervous cells are responsible for sensation and transportation of nerve impulses through neurons, which are the functional building unit of the nervous system.

Examples of Human Cells

  • Cuboidal epithelial cells have a round and central nucleus.
  • Smooth muscles cover internal organs and facilitate involuntary movements.
  • Neurons, or nerve cells, are formed from a soma or body and a long axon.

Cell Modification

  • Cell modification involves structural or functional changes that help cells perform specific functions.

Epithelial Cell Modification

  • Epithelial cells can be modified as epithelilal cells with brush boarders/microvilli, secretory cells, or basket cells.

Muscle Cell Modification

  • Smooth muscle cells modify as smooth muscle in internal human organs.

Nervous Cell Modification

  • Sensory cells, also known as neurons, are nervous cells that are modified.

Brush Boarders and Microvilli

  • Brush boarders are dense layers of microvilli on the surface of some epithelial cells.
  • Microvilli are tiny, finger-like projections on the surface of some epithelial cells.
  • The main function of microvilli is to increase the surface area for absorption.
  • Microvilli are primarily found in the small intestine and kidney tubules..
  • Under an electron microscope, a cuboidal epithelial cell with a brush boarder is visible, enhancing the surface area for absorption.
  • Brush borders are mainly in kidney tubules.

Ultra-structure of Epithelial Secretory Cells

  • Secretory epithelial cells contain secretory vacuoles, which are secreted from the rough endoplasmic reticulum (RER).
  • The main function of these cells is enzyme secretion.
  • These cells face the gastric cavity in the stomach and release digestive enzymes.

Ultra-structure of Smooth Muscles

  • Smooth muscles non-striated and involuntary.
  • Smooth muscles have an elongated nucleus and it is found in organs like stomach and small intestine.
  • The main function is for involuntary internal organs.

Ultra-structure of Neurons

  • Neurons (nerve cells) are the functional and structural unit of the nervous system.
  • Soma is the body of it. Nissl's bodies (group of RER and ribosomes) are the protein producers of neurons.

Ultra-structure of Basket Cells

  • Basket cells are modified epithelial cells that turn into myofibroblasts, becoming contractile.
  • Basket cells are found around glands.
  • Their main function is the squeezing of glands for excretion.

Sensory Cells

  • Sensory cells are the specialized cells that can identify the stimuli; light, sound, touch or even chemicals.
  • Sensory cells covert the stimuli into nerve impulses for the brain to process.
  • Sensory cells function as photoreceptors (in eyes), mechanoreceptors (in skin), and taste receptor cells (on tongue).

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