Uncover the World of Post-Translational Modifications

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Questions and Answers

Which of the following is NOT a classification of lipids mentioned in the text?

  • Phospholipids
  • Sphingolipids
  • Lipoproteins (correct)
  • Sterols

Which of the following amino acids is NOT considered essential?

  • Phenylalanine
  • Glycine (correct)
  • Valine
  • Methionine

Which level of protein structure is responsible for the compact folding of a protein, with hydrophobic amino acids on the inside and hydrophilic amino acids on the outside?

  • Quaternary structure
  • Primary structure
  • Tertiary structure (correct)
  • Secondary structure

Which of the following is NOT a function of native conformation of a protein?

<p>Denaturation (D)</p> Signup and view all the answers

Which of the following is NOT a level of protein structure?

<p>Quaternary structure (D)</p> Signup and view all the answers

Which of the following is true about post-translational modification of a protein?

<p>It can affect protein function (A)</p> Signup and view all the answers

What is the function of polysaccharides?

<p>Energy storage (B)</p> Signup and view all the answers

Which of the following is NOT a classification of lipids mentioned in the text?

<p>Lipoproteins and lipopolysaccharides (B)</p> Signup and view all the answers

Which of the following is the correct chain length and number of double bonds for arachidonic acid?

<p>20:4 (5,8,11,14) (B)</p> Signup and view all the answers

Which of the following is NOT a function of prostaglandins?

<p>Visual and neurologic abnormalities (C)</p> Signup and view all the answers

Which of the following is a major component of cell membranes?

<p>Phospholipids (C)</p> Signup and view all the answers

Which of the following is a post-translational modification (PTM) that results in a change in protein function?

<p>Phosphorylation (D)</p> Signup and view all the answers

Which of the following is a characteristic of monosaccharides?

<p>They have an empirical formula of (CH2O)n (C)</p> Signup and view all the answers

Which of the following is an example of a disaccharide?

<p>Lactose (B)</p> Signup and view all the answers

Which of the following is a major source of energy in the body?

<p>Lipids (B)</p> Signup and view all the answers

Which of the following is NOT a source of stem cells?

<p>Adult stem cells (A)</p> Signup and view all the answers

What is the process by which a less specialized cell becomes a more specialized cell type called?

<p>Cell differentiation (A)</p> Signup and view all the answers

Which of the following is NOT a fundamental aspect of developmental biology?

<p>Cellular respiration (B)</p> Signup and view all the answers

Which type of stem cells requires the destruction of an embryo?

<p>Embryonic stem cells (D)</p> Signup and view all the answers

What are the four transcription factors involved in genetic reprogramming of stem cells?

<p>Oct4, Sox2, Klf4, and c-Myc (D)</p> Signup and view all the answers

Which type of stem cells can be genetically matched to the patient?

<p>Induced pluripotent stem cells (C)</p> Signup and view all the answers

Which of the following is NOT one of the three types of cloning mentioned in the text?

<p>Live birth cloning (C)</p> Signup and view all the answers

What is the laboratory technique used to create a cloned embryo with a donor nucleus called?

<p>Somatic-Cell Transfer (SCT) (B)</p> Signup and view all the answers

Which type of stem cells have the potential to develop into a human embryo?

<p>Induced pluripotent stem cells (C)</p> Signup and view all the answers

What is the main goal of therapeutic cloning?

<p>To derive embryonic cell lines with the same genome as the nuclear donor (A)</p> Signup and view all the answers

Which type of stem cell is capable of making all types of specialized cells in the body?

<p>Embryonic stem cells (C)</p> Signup and view all the answers

Where are tissue stem cells found?

<p>Bone marrow (C)</p> Signup and view all the answers

Which type of stem cell is created through genetic reprogramming of adult cells?

<p>Induced pluripotent stem cells (B)</p> Signup and view all the answers

What is the potency of tissue stem cells?

<p>Multipotent (A)</p> Signup and view all the answers

Which of the following is the correct definition of anaemia?

<p>A condition where the number of red blood cells or their oxygen-carrying capacity is insufficient to meet physiological needs (D)</p> Signup and view all the answers

What is the WHO criteria for anaemia?

<p>Haemoglobin &lt; 12g/dL in non-pregnant women and &lt; 13g/dL in men (C)</p> Signup and view all the answers

Which of the following is NOT a type of anaemia mentioned in the text?

<p>Haemolytic anaemia (B)</p> Signup and view all the answers

Which type of genetic mutation results in the introduction of a stop codon?

<p>Nonsense/stop (B)</p> Signup and view all the answers

What is the main characteristic of cancer cells that allows for rapid evolution?

<p>Genomic instability (A)</p> Signup and view all the answers

Which type of genetic variation in malignant cells can lead to large scale deletions and amplifications?

<p>Chromosomal rearrangements (D)</p> Signup and view all the answers

Which of the following is the correct statement about human genetic variation?

<p>Human genomes have small-scale genetic variations like SNPs and microsatellites. (A)</p> Signup and view all the answers

What is the evolutionary purpose of sexual reproduction in humans?

<p>To introduce genetic differences into the population. (B)</p> Signup and view all the answers

What percentage of DNA bases are different between any two aligned human genomes?

<p>0.1% (A)</p> Signup and view all the answers

Which of the following is an example of large-scale pathogenic variation?

<p>Copy number variants (CNVs) (C)</p> Signup and view all the answers

Which of the following is NOT a feature of small-scale pathogenic mutations?

<p>Rearranging multiple genes (C)</p> Signup and view all the answers

Which of the following is an example of large-scale pathogenic variation that results in gross changes in gene expression?

<p>Trisomy 21 (A)</p> Signup and view all the answers

Which of the following is a common type of small-scale pathogenic variation?

<p>Insertions/deletions (C)</p> Signup and view all the answers

Which of the following is NOT a learning outcome of the course?

<p>Describe the mechanisms by which Gproteins regulate the effector enzymes (D)</p> Signup and view all the answers

How many times do G-protein coupled receptors pass through the membrane?

<p>7 (D)</p> Signup and view all the answers

Which subunit of the G-protein determines the activity status of the G-protein?

<p>α subunit (C)</p> Signup and view all the answers

Which of the following is NOT a second messenger produced during signal transduction?

<p>GTP (B)</p> Signup and view all the answers

Which of the following proteins inhibits adenylyl cyclase, thus turning off signaling?

<p>Gαi (B)</p> Signup and view all the answers

Which of the following is activated by cholera toxin and leads to elevated cAMP levels in the colonic epithelium?

<p>Adenylyl cyclase (D)</p> Signup and view all the answers

Which of the following second messengers binds to the IP3 receptor in the endoplasmic reticulum, resulting in calcium release?

<p>IP3 (B)</p> Signup and view all the answers

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