Podcast
Questions and Answers
Which benzodiazepine has a shorter half-life: Midazolam or Propofol?
Which benzodiazepine has a shorter half-life: Midazolam or Propofol?
In terms of sedation, which drug exhibits a more reliable amnesia: Midazolam or Propofol?
In terms of sedation, which drug exhibits a more reliable amnesia: Midazolam or Propofol?
Which of the following is NOT a clinical use of Benzodiazepines?
Which of the following is NOT a clinical use of Benzodiazepines?
What is a potential complication of using Benzodiazepines in patients with status epilepticus?
What is a potential complication of using Benzodiazepines in patients with status epilepticus?
Signup and view all the answers
Which organ system does Benzodiazepines have a modest effect on causing a decrease in blood pressure?
Which organ system does Benzodiazepines have a modest effect on causing a decrease in blood pressure?
Signup and view all the answers
What is the term used to describe the ideal form of euthanasia in war surgery?
What is the term used to describe the ideal form of euthanasia in war surgery?
Signup and view all the answers
How does respiratory depression occur when using Benzodiazepines?
How does respiratory depression occur when using Benzodiazepines?
Signup and view all the answers
Which type of barbiturates is associated with extreme excitation?
Which type of barbiturates is associated with extreme excitation?
Signup and view all the answers
How is barbiturate metabolism primarily carried out in the body?
How is barbiturate metabolism primarily carried out in the body?
Signup and view all the answers
Which type of barbiturate may lead to accumulation of the active metabolite pentobarbital at high doses?
Which type of barbiturate may lead to accumulation of the active metabolite pentobarbital at high doses?
Signup and view all the answers
What process results in the termination of action of a bolus dose of a drug due to redistribution?
What process results in the termination of action of a bolus dose of a drug due to redistribution?
Signup and view all the answers
What is the term for the time necessary for the effect site concentration to decrease by 50% relative to the duration of drug infusion?
What is the term for the time necessary for the effect site concentration to decrease by 50% relative to the duration of drug infusion?
Signup and view all the answers
What happens to thiopental kinetics with multiple bolus dosing or prolonged infusion?
What happens to thiopental kinetics with multiple bolus dosing or prolonged infusion?
Signup and view all the answers
In which patient population must thiopental induction doses be reduced?
In which patient population must thiopental induction doses be reduced?
Signup and view all the answers
What is the adult induction dose of methohexital compared to thiopental?
What is the adult induction dose of methohexital compared to thiopental?
Signup and view all the answers
Which barbiturate is sometimes chosen for electroconvulsive therapy (ECT)?
Which barbiturate is sometimes chosen for electroconvulsive therapy (ECT)?
Signup and view all the answers
Which barbiturate does not produce analgesia?
Which barbiturate does not produce analgesia?
Signup and view all the answers
What effect do barbiturates have on Cerebral Metabolic Rate of Oxygen (CMRO2) and Cerebral Blood Flow (CBF)?
What effect do barbiturates have on Cerebral Metabolic Rate of Oxygen (CMRO2) and Cerebral Blood Flow (CBF)?
Signup and view all the answers
Which organ system effect of ketamine involves the depression of cortex and thalamic areas?
Which organ system effect of ketamine involves the depression of cortex and thalamic areas?
Signup and view all the answers
What effect does ketamine have on the transmission of the affective-emotional component of nocioception?
What effect does ketamine have on the transmission of the affective-emotional component of nocioception?
Signup and view all the answers
Which of the following statements is true about ketamine?
Which of the following statements is true about ketamine?
Signup and view all the answers
What is one potential clinical use of low dose ketamine according to the text?
What is one potential clinical use of low dose ketamine according to the text?
Signup and view all the answers
Which organ system effect does ketamine NOT produce?
Which organ system effect does ketamine NOT produce?
Signup and view all the answers
'Interferes with nocioceptive central sensitization' is associated with which organ system effect of ketamine?
'Interferes with nocioceptive central sensitization' is associated with which organ system effect of ketamine?
Signup and view all the answers
What is a potential trigger of porphyria according to the text?
What is a potential trigger of porphyria according to the text?
Signup and view all the answers
Which side effect is more common with methohexital compared to thiopental?
Which side effect is more common with methohexital compared to thiopental?
Signup and view all the answers
What is the mechanism of action of ketamine that leads to intense analgesia and amnesia?
What is the mechanism of action of ketamine that leads to intense analgesia and amnesia?
Signup and view all the answers
What contributes to the brief duration of action of ketamine?
What contributes to the brief duration of action of ketamine?
Signup and view all the answers
Which clinical use does ketamine have at sub-anesthetic doses for analgesia?
Which clinical use does ketamine have at sub-anesthetic doses for analgesia?
Signup and view all the answers
In which situation is ketamine contraindicated for induction according to the text?
In which situation is ketamine contraindicated for induction according to the text?
Signup and view all the answers