Clinical biochemistry (Lec 8) (Set 1)

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Questions and Answers

Which of the following is a treatment for hyponatremia?

  • Increase fluid intake
  • Increase sodium intake
  • Restrict fluid intake (correct)
  • Administer diuretics

What is the normal range for potassium (K+) concentration in the blood?

  • 2.0-3.5 mmol/l
  • 5.0-7.0 mmol/l
  • 4.5-6.0 mmol/l
  • 3.5-5.0 mmol/l (correct)

Which of the following can lead to hyperkalemia?

  • Diarrhea
  • Vomiting
  • Renal failure (correct)
  • Adrenal failure

What are the clinical signs of hyponatremia?

<p>Tachycardia and hypotension (D)</p> Signup and view all the answers

Which of the following is a treatment for acute renal failure (ARF)?

<p>Oral or IV potassium (A)</p> Signup and view all the answers

What is the danger of rapid changes in potassium concentration in the blood?

<p>Dangerous cardiac arrhythmias (C)</p> Signup and view all the answers

What is the primary determinant of the resting potential of cells?

<p>Potassium (K+) (C)</p> Signup and view all the answers

Which of the following can cause hypokalemia?

<p>Vomiting (C)</p> Signup and view all the answers

What is the normal range for sodium (Na+) concentration in the blood?

<p>135-150 mmol/l (A)</p> Signup and view all the answers

Which of the following is a cause of hyponatremia?

<p>Lack of aldosterone (D)</p> Signup and view all the answers

Which of the following is true about urea and creatinine?

<p>Urea is a breakdown product of protein that occurs in the liver, while creatinine is produced in muscles. (D)</p> Signup and view all the answers

What happens to serum urea and creatinine if the Glomerular Filtration Rate (GFR) in the kidney is reduced?

<p>They increase (A)</p> Signup and view all the answers

Which hormone causes reabsorption of water in the collecting ducts?

<p>ADH (vasopressin) (C)</p> Signup and view all the answers

Which hormone causes reabsorption of sodium in the nephron and, consequently, water?

<p>Aldosterone (B)</p> Signup and view all the answers

What is the major site of sodium loss in non-renal associated disease?

<p>Gastrointestinal tract (GI tract) (B)</p> Signup and view all the answers

What is the normal range for sodium levels in the body?

<p>135-145 mmol/l (C)</p> Signup and view all the answers

What are the clinical signs of hypernatraemia (Na > 145mmol/l)?

<p>Increased blood pressure, decreased urine output, and dry mucous membranes (C)</p> Signup and view all the answers

What is the treatment for hypernatraemia?

<p>Oral water (D)</p> Signup and view all the answers

What are the clinical signs of hyponatraemia via water retention (Na < 135 mmol/l)?

<p>Decreased blood pressure, increased urine output, and moist mucous membranes (D)</p> Signup and view all the answers

What is the treatment for hyponatraemia via water retention?

<p>Diuretic and restrict fluid + treat condition (C)</p> Signup and view all the answers

True or false: Too much water reabsorbed by the kidney can lead to edema.

<p>False (B)</p> Signup and view all the answers

True or false: Hyponatremia is defined as a sodium level below 135 mmol/l.

<p>True (A)</p> Signup and view all the answers

True or false: Potassium concentration alterations can cause dangerous cardiac arrhythmias.

<p>True (A)</p> Signup and view all the answers

True or false: Hyperkalemia is defined as a potassium level above 4.9 mmol/l.

<p>True (A)</p> Signup and view all the answers

True or false: Acute renal failure can be characterized by anuria or oliguria.

<p>True (A)</p> Signup and view all the answers

True or false: Urea and electrolytes (‘U and Es’) are used to test a patient's fluid and electrolyte balance and renal function.

<p>True (A)</p> Signup and view all the answers

True or false: The kidney regulates extracellular fluid volume and electrolyte balance.

<p>True (A)</p> Signup and view all the answers

True or false: Serum urea and creatinine increase if the Glomerular Filtration Rate (GFR) in the kidney is reduced.

<p>True (A)</p> Signup and view all the answers

True or false: Sodium (Na) intake is balanced by loss mainly in the gastrointestinal tract (GI tract) in non-renal associated disease.

<p>True (A)</p> Signup and view all the answers

True or false: Hyponatremia can be caused by water retention and is treated with diuretics and fluid restriction.

<p>True (A)</p> Signup and view all the answers

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