Types of Penicillin Preparations
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Questions and Answers

Penicillin G procaine is an example of a natural penicillin.

False

Penicillin G procaine is obtained by altering the culture media with carboxylic acids.

False

The therapeutic serum level of Penicillin G procaine lasts about 3-6 hours.

True

Penicillin G procaine is eliminated slowly through the kidneys.

<p>False</p> Signup and view all the answers

Penicillin G procaine can be considered a semisynthetic penicillin.

<p>False</p> Signup and view all the answers

The use of Penicillin G procaine helps in addressing the short duration of action of Penicillin G.

<p>True</p> Signup and view all the answers

Penicillin G benzathine can be given orally due to its better acid stability than penicillin V.

<p>False</p> Signup and view all the answers

The acid sensitivity of penicillin G is attributed to three main factors: ring strain, a highly reactive gamma-lactam carbonyl group, and the influence of the alkyl chain.

<p>True</p> Signup and view all the answers

Penicillin G procaine is more sensitive to penicillinases compared to penicillin V.

<p>False</p> Signup and view all the answers

Ampicillin and oxacillin are solutions for addressing the acid sensitivity issue of penicillin G procaine.

<p>False</p> Signup and view all the answers

Penicillin V has a slightly higher activity level than penicillin G.

<p>False</p> Signup and view all the answers

Penicillin G shares with penicillin V the issue of allergic sensitivity in some individuals.

<p>False</p> Signup and view all the answers

Penicillins and cephalosporins inhibit the final cross-linking reaction in the cell wall biosynthesis.

<p>True</p> Signup and view all the answers

The enzyme responsible for the cross-linking reaction is called transpeptidase.

<p>True</p> Signup and view all the answers

Penicillins and cephalosporins lead to cell lysis by causing the cell wall to become less leaky.

<p>False</p> Signup and view all the answers

The structure of penicillin includes a thiazolidine ring and a beta-lactam ring.

<p>True</p> Signup and view all the answers

Penicillin V is also known as benzylpenicillin.

<p>False</p> Signup and view all the answers

Penicillin G procaine is a derivative of 6-aminopenicillanic acid (6-APA).

<p>True</p> Signup and view all the answers

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