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Questions and Answers
Which of the following is NOT a mechanism of insulin resistance in Type 2 Diabetes Mellitus?
Which of the following is NOT a mechanism of insulin resistance in Type 2 Diabetes Mellitus?
- Increased levels of resistin
- Oxidative stress
- High levels of adiponectin (correct)
- Subclinical inflammation
What is the main pathological process that leads to the development of hyperglycemia in Type 2 Diabetes Mellitus?
What is the main pathological process that leads to the development of hyperglycemia in Type 2 Diabetes Mellitus?
- Insulin resistance followed by insulinopenia (correct)
- Oxidative stress in muscle tissue
- Hypersecretion of insulin by beta cells
- Subclinical inflammation in adipose tissue
What is the primary cause of beta cell apoptosis in Type 2 Diabetes Mellitus?
What is the primary cause of beta cell apoptosis in Type 2 Diabetes Mellitus?
- Insulitis
- Glucotoxicity from hyperglycemia (correct)
- Amyloid deposits in islets
- Decreased incretin effect
In Type 2 Diabetes Mellitus, what happens to beta cell function over time?
In Type 2 Diabetes Mellitus, what happens to beta cell function over time?
What is the role of incretins in the regulation of insulin secretion?
What is the role of incretins in the regulation of insulin secretion?
Which factor contributes to beta cell failure in Type 2 Diabetes Mellitus by inducing apoptosis?
Which factor contributes to beta cell failure in Type 2 Diabetes Mellitus by inducing apoptosis?
What is the primary cause of beta cell loss in Type 1 Diabetes Mellitus?
What is the primary cause of beta cell loss in Type 1 Diabetes Mellitus?
Which human leukocyte antigen (HLA) accounts for 60% of the risk for Type 1 Diabetes Mellitus?
Which human leukocyte antigen (HLA) accounts for 60% of the risk for Type 1 Diabetes Mellitus?
Which of the following viruses is NOT associated with the development of Type 1 Diabetes Mellitus?
Which of the following viruses is NOT associated with the development of Type 1 Diabetes Mellitus?
What is the main genetic factor contributing to the risk of developing Type 1 Diabetes Mellitus?
What is the main genetic factor contributing to the risk of developing Type 1 Diabetes Mellitus?
What is the characteristic feature of the prediabetic stage of Type 1 Diabetes Mellitus?
What is the characteristic feature of the prediabetic stage of Type 1 Diabetes Mellitus?
Which factor plays a protective role against the development of Type 1 Diabetes Mellitus?
Which factor plays a protective role against the development of Type 1 Diabetes Mellitus?
What is the role of viruses in the pathogenesis of Type 1 Diabetes Mellitus?
What is the role of viruses in the pathogenesis of Type 1 Diabetes Mellitus?
Which of the following HLA types is considered a major risk factor for Type 1 Diabetes Mellitus?
Which of the following HLA types is considered a major risk factor for Type 1 Diabetes Mellitus?
What is the main role of autoantibodies in Type 1 Diabetes Mellitus?
What is the main role of autoantibodies in Type 1 Diabetes Mellitus?
What do pathological changes in the prediabetic stage of Type 1 Diabetes Mellitus primarily involve?
What do pathological changes in the prediabetic stage of Type 1 Diabetes Mellitus primarily involve?
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