Tumour Pathology: Oropharynx, Esophagus, Stomach

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20 Questions

Which genetic syndrome is associated with the development of gastric polyps of foveolar-type?

Familial adenomatous polyposis (FAP)

Which type of gastric polyp is most common in the distal stomach?

Hyperplastic polyp

What is the primary etiological factor for the development of intestinal-type adenomas?

Helicobacter pylori infection

Which of the following is NOT considered a malignant gastric tumor?

Fundic gland polyp

In which age group do adenomas (Intestinal-type or foveolar-type) commonly develop?

Sixth or seventh decade of life

What is the pathogenesis of hyperplastic polyps in the stomach related to?

Proton pump inhibitor use leading to glandular hyperplasia

What type of lesions can be associated with adenocarcinoma in the esophagus?

Fungating

What type of metaplasia is commonly seen in the adjacent mucosa of esophageal adenocarcinoma?

Barrett esophagus

Which characteristic is NOT typically observed in the morphology of malignant esophageal glands?

Stratified arrangement

Which of the following features is indicative of Barrett dysplasia?

Loss of nuclear polarity

Which type of adenocarcinoma is characterized by uninvolved normal squamous mucosa to the left?

Mucinous-producing invasive adenocarcinoma

Which type of carcinoma is most commonly associated with high-risk HPV, type 16, through oral sex?

Squamous cell carcinoma, HPV-positive

What is the main etiology factor for the development of Squamous papilloma in the esophagus?

Genetic syndromes

Where is the most common anatomical location for adenocarcinoma in the esophagus?

Lower third of the esophagus

Which of the following is NOT a risk factor for the development of esophageal adenocarcinoma?

Helicobacter pylori infection

What is the typical clinical presentation in the late stages of squamous cell carcinoma of the esophagus?

Dysphagia, chest pain, painful swallowing and weight loss

'Barrett esophagus' is a precursor lesion to which type of esophageal cancer?

Adenocarcinoma

'Koilocytes' are typically seen in histopathology slides of which esophageal condition?

Squamous papilloma

'Desmoplastic stroma' is a characteristic feature seen in which type of oropharyngeal squamous cell carcinoma?

'HPV-negative form'

Which factor has a higher association with HPV-positive oropharyngeal squamous cell carcinoma?

Sexual behavior

Test your knowledge on tumours of the oropharynx, esophagus, and stomach with Dr. Sarah binti Zulkarnain's lecture notes. Learn about different types of tumours in each area including squamous cell carcinoma, adenocarcinoma, papilloma, and polyps.

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