Tuberculosis Pathogenesis
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Questions and Answers

What happens to tubercle bacilli within macrophages during the first 3 weeks after exposure?

  • They escape from the macrophages
  • They are destroyed by the lysosome
  • They induce apoptosis in the macrophages
  • They replicate within the phagosome by blocking fusion to lysosome (correct)

    • What type of reaction is developed during the formation of granuloma and caseous necrosis due to tubercle bacilli infection?

  • Type III hypersensitivity reaction
  • Type IV hypersensitivity reaction (correct)
  • Type I hypersensitivity reaction
  • Type II hypersensitivity reaction

    • What happens about 3 weeks after infection with tubercle bacilli?

  • Tubercle bacilli are drained to lymph nodes and presented to T cells (correct)
  • Tubercle bacilli migrate to the lungs
  • Tubercle bacilli infect the liver
  • Tubercle bacilli are eliminated from the body

    • What is the initial response of most people after being exposed to tubercle bacilli?

    <p>Most people are asymptomatic (D)</p> Signup and view all the answers

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