Tryptophan Metabolism Quiz
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Questions and Answers

The conversion of tryptophan to 5-hydroxytryptophan is not considered a rate limiting step in the overall metabolic process.

False (B)

5-hydroxyindoleacetic acid (5-HIAA) is a product of the oxidative deamination of tryptophan.

True (A)

5-hydroxytryptophan is synthesized from tryptophan using the enzyme tryptophan decarboxylase.

False (B)

5-hydroxytryptamine (5-HT) is produced from 5-hydroxytryptophan through a non-specific hydroxylation reaction.

<p>False (B)</p> Signup and view all the answers

In the degradation of tryptophan, monoamine oxidase-B is more active than monoamine oxidase-A.

<p>False (B)</p> Signup and view all the answers

Flashcards

Tryptophan to 5-Hydroxytryptophan Conversion

The conversion of tryptophan to 5-hydroxytryptophan is the first and most important step in the synthesis of serotonin.

Tryptophan Degradation

Tryptophan is broken down by monoamine oxidase (MAO), mainly MAO-A, to produce 5-HIAA, which is excreted in urine.

What is serotonin?

A neurotransmitter derived from tryptophan that plays a role in mood, sleep, and appetite.

What is biosynthesis?

The process of creating a molecule from existing components, like synthesizing serotonin from tryptophan.

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What is degradation?

The breakdown of molecules into smaller components. An example is tryptophan degradation into 5-HIAA by MAO.

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