Podcast
Questions and Answers
What is the primary mechanism of action for triptans in treating migraines?
What is the primary mechanism of action for triptans in treating migraines?
- Causing vasodilation of cranial blood vessels
- Increasing serotonin levels in the central nervous system
- Causing vasoconstriction of cranial blood vessels (correct)
- Blocking dopamine receptors in the brain
Which of the following is a common route of administration for triptans?
Which of the following is a common route of administration for triptans?
- Oral (correct)
- Inhalation
- Intramuscular
- Transdermal
Which of the following is a contraindication for using triptans?
Which of the following is a contraindication for using triptans?
- Coronary artery disease (CAD) (correct)
- Type 2 diabetes
- Osteoporosis
- Hypothyroidism
For what condition are triptans indicated?
For what condition are triptans indicated?
What is a potential drug-drug interaction concern when prescribing triptans?
What is a potential drug-drug interaction concern when prescribing triptans?
Which of the following is an example of a triptan medication?
Which of the following is an example of a triptan medication?
What population group is generally contraindicated for the use of triptans?
What population group is generally contraindicated for the use of triptans?
Which route of administration allows for the fastest absorption of sumatriptan?
Which route of administration allows for the fastest absorption of sumatriptan?
A patient with a history of which condition should avoid eletriptan?
A patient with a history of which condition should avoid eletriptan?
If a patient experiences adverse effects from ergots, they are likely to experience similar effects from which drug class?
If a patient experiences adverse effects from ergots, they are likely to experience similar effects from which drug class?
Flashcards
Triptans: Mechanism & Use
Triptans: Mechanism & Use
Bind to serotonin receptors, causing cranial vessel vasoconstriction, used for acute migraine treatment, not prevention.
Common Triptan Names
Common Triptan Names
Sumatriptan, Naratriptan, Eletriptan
Triptan Routes of Administration
Triptan Routes of Administration
IV, Sub-Q, Oral
Triptan Contraindications
Triptan Contraindications
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Triptan Adverse Effects
Triptan Adverse Effects
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Triptan Drug Interaction
Triptan Drug Interaction
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Study Notes
Triptans
- Triptans selectively bind to serotonin receptor sites.
- This binding action induces vasoconstriction in cranial vessels.
- Triptans include Naratriptan, sumatriptan, and eletriptan.
- They are indicated for the acute treatment of migraines.
- They are not used to prevent migraines.
- Triptans can be administered intravenously, subcutaneously, or orally.
- Contraindications include elderly patients, coronary artery disease (CAD), pregnancy/lactation, and renal or hepatic dysfunction.
- Adverse effects mirror those of ergots.
- Triptans have a drug-drug interaction with ergots.
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