Podcast
Questions and Answers
What is the function of the α subunit of the Trimeric G Protein?
What is the function of the α subunit of the Trimeric G Protein?
- Inhibiting GTP hydrolysis
- Regulating GAP activity
- Enhancing GTP hydrolysis (correct)
- Promoting GPCR activation
Which role do RGS proteins play in the GTPase cycle of Trimeric G Proteins?
Which role do RGS proteins play in the GTPase cycle of Trimeric G Proteins?
- Enhancing GDP dissociation
- Acting as GAPs for α-subunit-specific GTPase activation (correct)
- Stimulating GTP hydrolysis
- Promoting GPCR activation
How does a Trimeric G Protein become inactive?
How does a Trimeric G Protein become inactive?
- By dissociating from the receptor
- By enhancing GTP hydrolysis
- By binding to GDP (correct)
- By promoting GPCR activation
Which component of the Trimeric G Protein has lipid molecules attached to help bind to the plasma membrane?
Which component of the Trimeric G Protein has lipid molecules attached to help bind to the plasma membrane?
What is the function of Guanine Exchange Factors (GEFs) in the GTPase cycle of Trimeric G Proteins?
What is the function of Guanine Exchange Factors (GEFs) in the GTPase cycle of Trimeric G Proteins?
How do GAPs regulate Trimeric G Proteins?
How do GAPs regulate Trimeric G Proteins?
What is the role of a Guanine Exchange Factor (GEF) in GPCR signaling?
What is the role of a Guanine Exchange Factor (GEF) in GPCR signaling?
How many subunits make up a Trimeric G protein?
How many subunits make up a Trimeric G protein?
What happens to the α-subunit of a Trimeric G protein in its unstimulated state?
What happens to the α-subunit of a Trimeric G protein in its unstimulated state?
Which part of the Trimeric G protein binds to GDP in its inactive state?
Which part of the Trimeric G protein binds to GDP in its inactive state?
How does the ligand binding to a GPCR affect the associated Trimeric G protein?
How does the ligand binding to a GPCR affect the associated Trimeric G protein?
Where does the ligand bind in a typical Trimeric GPCR structure?
Where does the ligand bind in a typical Trimeric GPCR structure?
What is the role of Guanine nucleotide-dissociation inhibitors (GDIs) in G protein signaling?
What is the role of Guanine nucleotide-dissociation inhibitors (GDIs) in G protein signaling?
How do Regulatory proteins of G protein Signalling (RGS) contribute to G protein responses?
How do Regulatory proteins of G protein Signalling (RGS) contribute to G protein responses?
How many RGS proteins are encoded in the human genome?
How many RGS proteins are encoded in the human genome?
Which of the following families of trimeric G proteins are involved in GPCR signaling pathways?
Which of the following families of trimeric G proteins are involved in GPCR signaling pathways?
What is the signaling effect of cAMP activation by Gs on plasma membrane-bound enzymes?
What is the signaling effect of cAMP activation by Gs on plasma membrane-bound enzymes?
