Treponema Pallidum Protein Synthesis Inhibitors Quiz
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Questions and Answers

What is the target of amoxicillin?

  • DNA replication in the bacteria
  • Cell wall synthesis in the bacteria (correct)
  • Protein synthesis in the host cell
  • Viral replication within the host cell

Why is Treponema pallidum considered an obligate parasite?

  • It can only live inside a host cell (correct)
  • It causes spiral-shaped infections
  • It is challenging to grow in a lab environment
  • It has a small genome

What makes it hard to determine the virulence factors of Treponema pallidum?

  • The need for co-culture with bacteria
  • Its small genome size
  • The difficulty in growing it on solid media (correct)
  • Its ability to form spores

How does Treponema pallidum maintain fluidity in its cell membranes?

<p>By cholesterol synthesis (A)</p> Signup and view all the answers

Which antibiotic is commonly used to inhibit protein synthesis in bacteria?

<p>Doxycycline (B)</p> Signup and view all the answers

Why is Treponema pallidum described as the 3rd leading cause of STDs in the U.S.?

<p>The persistence of the bacteria (D)</p> Signup and view all the answers

What type of environment is most suitable for the growth of Treponema pallidum?

<p>A nutrient-rich environment (B)</p> Signup and view all the answers

What is responsible for the motility of the bacteria described in the text?

<p>Internal flagella (B)</p> Signup and view all the answers

Why are the bacteria described in the text unable to make their own amino acids, fatty acids, and nucleotides?

<p>They are dependent on scavenging from the environment (D)</p> Signup and view all the answers

How do the described bacteria remodel their outer surface proteins to evade antibody clearance?

<p>By altering their outer surface proteins (C)</p> Signup and view all the answers

What is a characteristic of the segmented genome of the bacteria mentioned in the text?

<p>It has linear, not circular, chromosomes (D)</p> Signup and view all the answers

How do female ticks acquire an infection from the bacteria described in the text?

<p>Through migration of bacteria from their gut to their saliva (B)</p> Signup and view all the answers

What is one reason why humans and dogs are considered accidental hosts for the bacteria described in the text?

<p>They cannot pass the bacteria on to new ticks (B)</p> Signup and view all the answers

Why might people of color have a greater risk of missing a diagnosis of a disease caused by these bacteria?

<p>Their symptoms may not present as typically expected (D)</p> Signup and view all the answers

What is the primary reason that the hypostome calcified harpoon structure of a tick makes it difficult to remove the tick's mouthparts?

<p>It attaches securely to the host's skin, making it challenging to pull out. (D)</p> Signup and view all the answers

Why is Lyme Disease transmission more rapid when a tick is unfed compared to when it has recently fed small meals?

<p>The tick's saliva contains spiral bacteria that aid in rapid transmission after feeding. (C)</p> Signup and view all the answers

Why does the confirmatory diagnosis for tick-borne diseases require producing antibodies against the bacteria through serology?

<p>To distinguish between a current infection and a previous exposure to the disease. (A)</p> Signup and view all the answers

What is the significance of the spike in bacteria levels in the blood on days 5-6 of a relapsing fever infection?

<p>The spike correlates with the time when the bacteria change their outer surface proteins. (B)</p> Signup and view all the answers

What makes ticks attracted to sleepers in areas like Sub-Saharan Africa, similar to how they are attracted to carbon dioxide?

<p>They are drawn to warmth, sweat, and body odor emitted during sleep. (C)</p> Signup and view all the answers

Why is Treponema pallidum not an effective treatment for relapsing fever bacteria despite being effective against syphilis?

<p>The outer surface proteins of relapsing fever bacteria prevent recognition by Treponema pallidum antibodies. (C)</p> Signup and view all the answers

What differentiates Borrelia recurrentis from Borrelia hermsii in causing relapsing fever infections?

<p>'Borrelia recurrentis' transmits relapsing fever through ticks, while 'Borrelia hermsii' transmits it through lice. (A)</p> Signup and view all the answers

How does the presence of endotoxin in tick saliva potentially contribute to septic shock in tick-borne infections?

<p>'Endotoxin' induces a systemic inflammatory response that can lead to septic shock. (B)</p> Signup and view all the answers

Why do patients with relapsing fever often undergo specific serology tests like LBRF for antibodies rather than immediate antibiotic treatment?

<p>'LBRF' serology tests confirm if fevers are caused by relapsing fever or other tick-borne illnesses. (D)</p> Signup and view all the answers

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