Podcast
Questions and Answers
Which of the following is a difference between dissolved and hemoglobin-bound oxygen?
Which of the following is a difference between dissolved and hemoglobin-bound oxygen?
What is the relationship between PaO2 and % saturation of hemoglobin (Hgb)?
What is the relationship between PaO2 and % saturation of hemoglobin (Hgb)?
What are the variables that influence the Hgb-O2 dissociation curve?
What are the variables that influence the Hgb-O2 dissociation curve?
What are the different forms of CO2 in blood?
What are the different forms of CO2 in blood?
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How do the O2 and CO2 dissociation curves compare and contrast?
How do the O2 and CO2 dissociation curves compare and contrast?
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Study Notes
Oxygen Transport
- Dissolved oxygen and hemoglobin-bound oxygen differ in that dissolved oxygen is transported in the blood plasma, whereas hemoglobin-bound oxygen is transported bound to hemoglobin in red blood cells.
- PaO2 (partial pressure of oxygen) is directly related to the percentage of hemoglobin (Hgb) saturation, with higher PaO2 values resulting in higher Hgb saturation.
Factors Influencing Hgb-O2 Dissociation Curve
- The Hgb-O2 dissociation curve is influenced by variables such as pH, temperature, and 2,3-bisphosphoglycerate (2,3-BPG) levels, which can shift the curve to the right or left.
CO2 Transport
- CO2 in blood exists in three forms: dissolved CO2, carbaminohemoglobin, and bicarbonate ions.
O2 and CO2 Dissociation Curves
- The O2 and CO2 dissociation curves are inversely related, with the O2 curve being sigmoidal and the CO2 curve being more linear.
- The O2 curve is shifted to the right by factors such as increased temperature, decreased pH, and increased 2,3-BPG levels, whereas the CO2 curve is shifted to the left by these factors.
- The O2 curve is influenced by the binding of O2 to hemoglobin, whereas the CO2 curve is influenced by the buffering of H+ ions by bicarbonate.
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Description
Test your knowledge on the transport of oxygen (O2) and carbon dioxide (CO2) in the blood with this informative quiz. Explore the key concepts and mechanisms involved in this vital process.