5 Questions
Which of the following is a difference between dissolved and hemoglobin-bound oxygen?
Dissolved oxygen is carried in the blood plasma, while hemoglobin-bound oxygen is carried by red blood cells.
What is the relationship between PaO2 and % saturation of hemoglobin (Hgb)?
As PaO2 increases, % saturation of Hgb increases.
What are the variables that influence the Hgb-O2 dissociation curve?
Temperature and pH
What are the different forms of CO2 in blood?
Dissolved CO2, bicarbonate ions, and carbaminohemoglobin
How do the O2 and CO2 dissociation curves compare and contrast?
The O2 dissociation curve is linear, while the CO2 dissociation curve is sigmoidal.
Study Notes
Oxygen Transport
- Dissolved oxygen and hemoglobin-bound oxygen differ in that dissolved oxygen is transported in the blood plasma, whereas hemoglobin-bound oxygen is transported bound to hemoglobin in red blood cells.
- PaO2 (partial pressure of oxygen) is directly related to the percentage of hemoglobin (Hgb) saturation, with higher PaO2 values resulting in higher Hgb saturation.
Factors Influencing Hgb-O2 Dissociation Curve
- The Hgb-O2 dissociation curve is influenced by variables such as pH, temperature, and 2,3-bisphosphoglycerate (2,3-BPG) levels, which can shift the curve to the right or left.
CO2 Transport
- CO2 in blood exists in three forms: dissolved CO2, carbaminohemoglobin, and bicarbonate ions.
O2 and CO2 Dissociation Curves
- The O2 and CO2 dissociation curves are inversely related, with the O2 curve being sigmoidal and the CO2 curve being more linear.
- The O2 curve is shifted to the right by factors such as increased temperature, decreased pH, and increased 2,3-BPG levels, whereas the CO2 curve is shifted to the left by these factors.
- The O2 curve is influenced by the binding of O2 to hemoglobin, whereas the CO2 curve is influenced by the buffering of H+ ions by bicarbonate.
Test your knowledge on the transport of oxygen (O2) and carbon dioxide (CO2) in the blood with this informative quiz. Explore the key concepts and mechanisms involved in this vital process.
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