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Questions and Answers
What effect does 2,3-BPG have on the oxygen affinity of hemoglobin?
What effect does 2,3-BPG have on the oxygen affinity of hemoglobin?
- Stabilizes the T conformation
- Decreases the oxygen affinity (correct)
- Increases the oxygen affinity
- Has no effect on the oxygen affinity
Where does 2,3-BPG bind on hemoglobin?
Where does 2,3-BPG bind on hemoglobin?
- To a pocket formed by two beta-globin chains (correct)
- To the heme group
- To the oxygen molecule
- To the alpha-globin chain
What happens to 2,3-BPG levels in response to chronic hypoxia or anemia?
What happens to 2,3-BPG levels in response to chronic hypoxia or anemia?
- Decreases
- Increases (correct)
- Turns into oxyhemoglobin
- Remains unchanged
What is the primary function of myoglobin?
What is the primary function of myoglobin?
What is the role of 2,3-Bis-phospho glycerate (2,3 BPG) in relation to hemoglobin?
What is the role of 2,3-Bis-phospho glycerate (2,3 BPG) in relation to hemoglobin?
What is the primary difference between myoglobin and hemoglobin?
What is the primary difference between myoglobin and hemoglobin?
What is the significance of the steep slope in the oxygen dissociation curve?
What is the significance of the steep slope in the oxygen dissociation curve?
What is the effect of O2 binding on hemoglobin in the lungs?
What is the effect of O2 binding on hemoglobin in the lungs?
How does myoglobin differ from hemoglobin in terms of oxygen binding?
How does myoglobin differ from hemoglobin in terms of oxygen binding?
How does the binding of the 1st O2 molecule affect the remaining heme groups in the same hemoglobin molecule?
How does the binding of the 1st O2 molecule affect the remaining heme groups in the same hemoglobin molecule?
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