Transport of Gases and Protein Structure Lecture Quiz

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What effect does 2,3-BPG have on the oxygen affinity of hemoglobin?

Stabilizes the T conformation

Decreases the oxygen affinity (correct)

Increases the oxygen affinity

Has no effect on the oxygen affinity

Where does 2,3-BPG bind on hemoglobin?

To a pocket formed by two beta-globin chains (correct)

To the heme group

To the oxygen molecule

To the alpha-globin chain

What happens to 2,3-BPG levels in response to chronic hypoxia or anemia?

Decreases

Increases (correct)

Turns into oxyhemoglobin

Remains unchanged

What is the primary function of myoglobin?

Serving as an oxygen reservoir in muscle cells Signup and view all the answers

What is the role of 2,3-Bis-phospho glycerate (2,3 BPG) in relation to hemoglobin?

Stabilizing the structure of hemoglobin Signup and view all the answers

What is the primary difference between myoglobin and hemoglobin?

Myoglobin consists of a single polypeptide chain, while hemoglobin consists of multiple subunits Signup and view all the answers

What is the significance of the steep slope in the oxygen dissociation curve?

It allows hemoglobin to carry and deliver oxygen efficiently from areas of high to low oxygen concentration. Signup and view all the answers

What is the effect of O2 binding on hemoglobin in the lungs?

The hemoglobin becomes saturated with O2. Signup and view all the answers

How does myoglobin differ from hemoglobin in terms of oxygen binding?

Myoglobin cannot achieve the same degree of O2 release within a range of partial pressures of O2 as hemoglobin. Signup and view all the answers

How does the binding of the 1st O2 molecule affect the remaining heme groups in the same hemoglobin molecule?

It increases the O2 affinity of the remaining heme groups. Signup and view all the answers

Transport of Gases and Protein Structure Lecture Quiz

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Questions and Answers

What effect does 2,3-BPG have on the oxygen affinity of hemoglobin?

Where does 2,3-BPG bind on hemoglobin?

What happens to 2,3-BPG levels in response to chronic hypoxia or anemia?

What is the primary function of myoglobin?

What is the role of 2,3-Bis-phospho glycerate (2,3 BPG) in relation to hemoglobin?

What is the primary difference between myoglobin and hemoglobin?

What is the significance of the steep slope in the oxygen dissociation curve?

What is the effect of O2 binding on hemoglobin in the lungs?

How does myoglobin differ from hemoglobin in terms of oxygen binding?

How does the binding of the 1st O2 molecule affect the remaining heme groups in the same hemoglobin molecule?

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