Transport of CO2 in Respiratory Physiology

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Questions and Answers

What is the approximate CO2 content in arterial blood when the partial pressure of CO2 (PCO2) is 46mmHg?

  • 52ml/dl (correct)
  • 48ml/dl
  • 56ml/dl
  • 45ml/dl

What is the primary mechanism by which CO2 is transported in the blood?

  • Physical solution in plasma
  • Bound to hemoglobin in red blood cells
  • As bicarbonate ions in plasma
  • All of the above (correct)

What is the significance of the Haldane effect?

  • It facilitates the release of oxygen from hemoglobin in the tissues
  • It facilitates the release of CO2 from the blood in the lungs (correct)
  • It facilitates the uptake of oxygen by hemoglobin in the lungs
  • It facilitates the uptake of CO2 by the blood in the tissues

How does the Bohr effect influence oxygen delivery to the tissues?

<p>It shifts the oxygen dissociation curve to the right, decreasing oxygen affinity to hemoglobin (B)</p> Signup and view all the answers

Which of the following scenarios directly contributes to the Bohr effect?

<p>Increased metabolic activity in the tissues (B)</p> Signup and view all the answers

Flashcards

CO2 content in arterial blood

The total amount of CO2 present in the arterial blood, totaling 48 ml/dl.

Tidal CO2

The average CO2 transported from tissues to lungs, about 4 ml per 100 ml of blood.

CO2 dissociation curve

Graph showing the relationship between CO2 content of blood and CO2 tension (PCO2).

Haldane Effect

Oxygen binding to hemoglobin in lungs causes the release of CO2 from blood to alveoli.

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Bohr Effect

Increased CO2 and H+ cause the oxygen dissociation curve to shift right, aiding oxygen release to tissues.

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Study Notes

Transport of CO2

  • CO2 content in arterial blood: 48ml/dL
  • Physical solution: 3ml/dL
  • Chemical combination in plasma and RBCs: 45ml/dL
  • Tidal CO2: 4 ml of CO2 is transported from tissues to lungs in each 100 ml of blood during resting conditions
  • CO2 dissociation Curve: illustrates the relationship between total CO2 content in blood and CO2 tension (PCO2)

At the Lungs

  • PCO2 = 40mmHg → CO2 content = 48ml/dL
  • At the tissues: PCO2 = 46mmHg → CO2 content = 52ml/dL

Haldane Effect

  • Oxygen binding to hemoglobin in the lungs displaces/releases CO2 from blood to alveoli

Bohr Effect

  • Increased CO2 and H+ shift the oxygen dissociation curve to the right
  • Facilitates oxygen release to tissues

Important Effect

  • Haldane effect is more important than Bohr effect.

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