Transport Across Cell Membrane
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Questions and Answers

What are the two main types of transport across the cell membrane?

  • Simple Diffusion and Facilitated Diffusion
  • Diffusion and Osmosis
  • Facilitated Diffusion and Active Transport
  • Passive Transport and Active Transport (correct)
  • What are the two types of passive transport?

  • Osmosis and Diffusion
  • Simple Diffusion and Facilitated Diffusion (correct)
  • Endocytosis and Exocytosis
  • Primary Active Transport and Secondary Active Transport
  • Simple diffusion requires energy.

    False (B)

    Facilitated diffusion requires energy.

    <p>False (B)</p> Signup and view all the answers

    Active transport requires a carrier protein.

    <p>True (A)</p> Signup and view all the answers

    Active transport requires energy.

    <p>True (A)</p> Signup and view all the answers

    Passive transport does not require energy.

    <p>True (A)</p> Signup and view all the answers

    What does the term 'osmosis' mean and how is it different from simple diffusion?

    <p>Osmosis is the passive movement of water across a semi permeable membrane from a region of higher water concentration to a region of lower water concentration. It is different from simple diffusion as it is specifically about the movement of water across a membrane rather than other substances.</p> Signup and view all the answers

    What are the main ways ions move across the cell membrane?

    <p>Ions can move across the cell membrane through ion channels, which are specific protein pores that allow the passage of certain ions. There are several types of ion channels: leakage channels, which are always open, voltage-gated channels, which open in response to changes in membrane potential, and ligand-gated channels, which open in response to the binding of a specific molecule.</p> Signup and view all the answers

    What is the function of sodium potassium pumps?

    <p>Sodium-potassium pumps are active transporter proteins that use ATP to pump sodium ions out of the cell and potassium ions into the cell. They maintain the concentration gradients of sodium and potassium across the cell membrane, which is essential for nerve impulse conduction and maintaining cell volume.</p> Signup and view all the answers

    What is 'Transport Maximum' and what determines it?

    <p>Transport maximum is the maximum rate at which a substance can be transported across a membrane using a carrier protein. It is determined by the number of carrier proteins present in the membrane. In some cases, factors like hormones can also influence the number of carriers.</p> Signup and view all the answers

    Match the following types of transport with their descriptions:

    <p>Simple Diffusion = Movement of substances across a membrane without the use of energy, following the concentration gradient Facilitated Diffusion = Movement of substances across a membrane with the help of carrier proteins, but still without requiring energy, following the concentration gradient Active Transport = Movement of substances across a membrane against their concentration gradient, requiring energy and often involving carrier proteins Endocytosis = Process by which cells engulf particles or molecules from outside the cell, forming a vesicle Exocytosis = Process by which cells release particles or molecules from inside the cell, by fusing a vesicle containing these substances with the cell membrane</p> Signup and view all the answers

    Flashcards

    Passive Transport

    Movement of substances across cell membrane without requiring energy.

    Active Transport

    Movement of substances across cell membrane requiring energy.

    Simple Diffusion

    Simple diffusion occurs directly through the cell membrane from high concentration to low concentration, doesn't need a carrier protein.

    Concentration Gradient

    Movement of substances according to its concentration gradient, from high concentration to low concentration.

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    Fick's Law of Diffusion

    The rate of diffusion is affected by factors like the size of the molecule, solubility in the membrane, temperature, and surface area.

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    Leakage Channels

    Watery pathways through integral protein part of cell membrane that allow specific ions to pass through.

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    Gated Channels

    Channels that open or close in response to a specific stimulus, such as change in voltage or the binding of a ligand.

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    Ligand-Gated Channels

    Gated channels that open or close in response to the binding of specific molecules, like neurotransmitters.

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    Voltage-Gated Channels

    Gated channels that open or close in response to changes in the electrical potential across the membrane.

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    Facilitated Diffusion

    A type of passive transport that involves the movement of substances across the membrane with the aid of carrier proteins, following the concentration gradient.

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    Transport Maximum

    The maximum rate at which a carrier protein can transport a specific solute, determined by the number of carriers.

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    Primary Active Transport

    A type of active transport that directly uses energy (ATP) from the breakdown of ATP to move substances across the membrane against their concentration gradient.

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    Sodium-Potassium Pump

    A carrier protein that pumps sodium ions out of the cell and potassium ions into the cell, maintaining concentration gradients and contributing to cell membrane potential.

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    Secondary Active Transport

    A type of active transport that uses the energy stored in the concentration gradient of one substance to move another substance across the membrane against its concentration gradient.

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    Cotransport

    Secondary active transport where the two substances move in the same direction across the membrane.

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    Countertransport

    Secondary active transport where the two substances move in opposite directions across the membrane.

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    Exocytosis

    Process of transporting substances from inside the cell to the outside of the cell.

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    Endocytosis

    Process of transporting substances from the outside of the cell to the inside of the cell.

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    Phagocytosis

    A type of endocytosis where the cell engulfs large particles, like bacteria or debris.

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    Osmosis

    The movement of water across a semipermeable membrane from an area of high water concentration to an area of low water concentration, or from an area of low solute concentration to an area of high solute concentration.

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    Osmotic Pressure

    The pressure required to prevent the movement of water across a semipermeable membrane from a diluted solution to a concentrated solution.

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    Isotonic Solution

    A solution with the same solute concentration as the inside of the cell.

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    Hypotonic Solution

    A solution with a lower solute concentration than the inside of the cell.

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    Hypertonic Solution

    A solution with a higher solute concentration than the inside of the cell.

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    Hypotonic Solution

    A solution with a lower solute concentration than the inside of the cell, causing water to move into the cell, which can cause swelling or even bursting.

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    Hypertonic Solution

    A solution with a higher solute concentration than the inside of the cell, causing water to move out of the cell, which can cause shrinking or dehydration.

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    Study Notes

    Transport Across the Cell Membrane

    • Transport across cell membranes is either passive or active.
    • Passive transport does not require energy; active transport does.
    • Passive transport includes simple diffusion and facilitated diffusion.
    • Active transport can be primary or secondary.

    Objectives

    • Differentiate between types of cellular transport.
    • Identify different channel and carrier types.
    • Explain how macromolecules cross cell membranes.
    • Define osmosis and osmotic pressure.

    Simple Diffusion

    • A passive transport mechanism.
    • No energy required.
    • Movement of particles from high to low concentration.
    • Affected by Fick's Law of diffusion.
    • Rate of diffusion is influenced by permeability coefficient, concentration gradient, surface area, and membrane thickness.
    • Also affected by the substance's solubility and molecular weight.

    Fick's Law of Diffusion

    • Diffusion rate is directly proportional to the:
      • Permeability coefficient
      • Concentration gradient
      • Surface area
    • Diffusion rate is inversely proportional to membrane thickness.

    Demonstration of Diffusion in Fluids and Effect of Temperature

    • Temperature increases the rate of diffusion.
    • Procedure includes placing methylene blue crystals in beakers of varying water temperatures (cold, room temperature, hot) and observing the time it takes for the dye to disperse.

    Ion Channels

    • Important for ion diffusion.
    • Includes leakage channels, voltage-gated channels, and ligand-gated channels.
    • Ions move based on their electrochemical gradients.

    Leakage Channels

    • Watery pathways through integral proteins.
    • Tubed shape, extending from the extracellular fluid (ECF) to the intracellular fluid (ICF).
    • Highly selective channels.
    • Examples: Na+ and K+ leakage channels.

    Facilitated Diffusion

    • Passive transport that follows the concentration gradient.
    • Does not require energy.
    • Relies on carrier proteins.
    • Has a transport maximum.
    • Example: glucose transport.

    Transport Maximum (Tm)

    • The maximum rate at which a particular substance can be transported.
    • Dependent on the number of carrier proteins available.
    • Influenced by hormones (e.g., insulin).
    • Reduced in certain conditions (e.g., diabetes).

    Active Transport

    • Movement of substances against their concentration gradient.
    • Requires energy.
    • Uses carrier proteins.
    • Types include primary and secondary active transport.

    Primary Active Transport

    • ATPase activity of the carrier protein.
    • Examples: Na+/K+ pump, Ca2+ pump, H+/K+ pump.

    Secondary Active Transport

    • Depends on the sodium gradient established by the Na+/K+ pump.
    • Either cotransport or countertransport.

    Exocytosis

    • Transport of substances out of the cell.
    • Active process that requires energy.

    Endocytosis

    • Transport of substances into the cell.
    • Active process that requires energy.
    • Includes phagocytosis (ingestion of large particles).

    Osmosis

    • Passive transport of water across a selectively permeable membrane.
    • Movement from high water concentration to low water concentration or from low solute concentration to high solute concentration.

    Osmotic Pressure

    • Pressure needed to prevent water movement across a selectively permeable membrane.

    Hypertonic Solution

    • Solute concentration outside the cell is higher than inside.
    • Water moves out of the cell.
    • Cell shrinks (crenation).

    Hypotonic Solution

    • Solute concentration outside the cell is lower than inside.
    • Water moves into the cell.
    • Cell swells (lysis).

    Isotonic Solution

    • Solute concentration inside and outside the cell is equal.
    • No net water movement.

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    Description

    This quiz covers the mechanisms of transport across cell membranes, emphasizing passive and active transport types. Learn to differentiate between simple diffusion and facilitated diffusion, as well as explore how macromolecules traverse cell membranes. Understand key concepts such as osmosis and the factors influencing diffusion rates.

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