Podcast Beta
Questions and Answers
(a) Describe the process of translation. (3 marks)
Any 3 points from the following:
The ribosome reads mRNA a codon (3 bases) at a time
tRNA molecules carry amino acid to mRNA
complementary anti-codon binds with codon
tRNA releases amino acid
peptide bonds form between amino acids (as process is repeated for each codon)
(b) Define epigenetics. (2 marks)
the study of changes in gene expression
in env factors that can cause genomic changes that are inherited by offspring that do not alter DNA sequence
(c) Describe how histone acetylation can lead to differences in gene expression. (4 marks)
Addition of an acetyl group (CH3CO) to the histone protein tail
This relaxes or unwinds the chromatin
DNA is exposed and transcription promoted
Promotes transcription; allowing RNA polymerase to access nucleotides (to copy mRNA)
(b) Explain the role of the nucleus in protein synthesis. (4 marks)
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The enzymes DNA helicase and DNA polymerase are involved in DNA replication. Describe the functions of these enzymes.
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Define the term epigenetics and explain how chromatin modification can affect gene expression. (9 marks) Definition (3 mark) Acetylation (3 marks) Methylation (3 marks)
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- Outline the process that would result in the PRODUCTION of a protein FROM a strand of mRNA.
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compare and contrast DNA with mDNA
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Compare the processes of meiosis and mitosis. Explain why each process is important in humans.
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