Podcast
Questions and Answers
What is the rate of mRNA synthesis during the transcription elongation phase?
What is the rate of mRNA synthesis during the transcription elongation phase?
- 80 nucleotides per second
- 40 nucleotides per second (correct)
- 10 nucleotides per second
- 100 nucleotides per second
In which direction is mRNA synthesized during the transcription elongation phase?
In which direction is mRNA synthesized during the transcription elongation phase?
- Neither, it's randomized
- 5' to 3' direction (correct)
- 3' to 5' direction
- Bidirectional
What is the primary function of the RNA polymerase during the transcription elongation phase?
What is the primary function of the RNA polymerase during the transcription elongation phase?
- To act as a stable linker between the DNA template and the nascent RNA strands (correct)
- To unwind the DNA template
- To synthesize proteins
- To release the σ subunit
What happens to the DNA template during the transcription elongation phase?
What happens to the DNA template during the transcription elongation phase?
What event initiates the transcription elongation phase?
What event initiates the transcription elongation phase?
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Study Notes
Transcription Elongation Phase
- Begins with the release of the σ subunit from the polymerase, allowing the core enzyme to proceed along the DNA template
- mRNA is synthesized in the 5' to 3' direction at a rate of approximately 40 nucleotides per second
- During elongation, the DNA is continuously unwound ahead of the core enzyme and rewound behind it
Importance of RNA Polymerase
- Acts as a stable linker between the DNA template and the nascent RNA strands
- Ensures that elongation is not interrupted prematurely, as base pairing between DNA and RNA is not stable enough to maintain the stability of the mRNA synthesis components
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