TPGS Pharmaceutical and Nutraceutical Uses Quiz
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Questions and Answers

What is the main benefit of high-grade TPGS in pharmaceutical and nutraceutical industries?

  • Improving taste of medications
  • Reducing manufacturing costs
  • Enhancing absorption of health-transforming ingredients (correct)
  • Increasing shelf life of products

Why does Quicksilver Scientific use high-grade TPGS as a PEG source despite its higher cost?

  • To extend product shelf life
  • To enhance the absorption of ingredients (correct)
  • To reduce manufacturing time
  • To improve drug taste

In what condition did d-α-tocopheryl polyethylene glycol-1000 succinate show enhanced absorption of vitamin D?

  • Chronic cholestatic liver disease (correct)
  • Chronic kidney disease
  • Diabetes mellitus
  • Hyperthyroidism

What distinguishes the cost of high-grade TPGS from other commercial PEG types?

<p>High-grade TPGS is 5-10 times more expensive (C)</p> Signup and view all the answers

What is the main function of d-alpha-tocopheryl polyethylene glycol-1000 succinate in treating vitamin E deficiency during childhood cholestasis?

<p>To increase the absorption of vitamin E (B)</p> Signup and view all the answers

Why are lipid vesicles used in drug delivery systems?

<p>To protect substances from degradation by gastric juices. (C)</p> Signup and view all the answers

What is a key advantage of lipid nanoparticle delivery systems?

<p>They improve absorption of substances with poor bioavailability. (B)</p> Signup and view all the answers

How do liposomal delivery systems enhance the delivery of glutathione?

<p>By protecting it from breakdown in the digestive system. (D)</p> Signup and view all the answers

What is the role of optimally-sized liposomes in drug delivery systems?

<p>To prolong the time the therapeutic core remains in circulation. (B)</p> Signup and view all the answers

Why are liposomal delivery systems ideal for delivering substances with a prolonged systemic effect?

<p>Because they protect substances from degradation in gastric juices. (B)</p> Signup and view all the answers

What is a common symptom associated with consumption of meals high in fat?

<p>Generalized itching (D)</p> Signup and view all the answers

When are symptoms of pruritis in cholestasis typically worse in women?

<p>Before sleep or at night (A)</p> Signup and view all the answers

What additional symptoms may a person with cholestasis experience due to liver 'backfire'?

<p>Fatigue and impaired memory (D)</p> Signup and view all the answers

Which condition in pregnant women should prompt consultation with a physician before using a product?

<p>Cholestasis (A)</p> Signup and view all the answers

What type of symptoms may suggest the presence of primary biliary cholangitis?

<p>Fatigue and itching (B)</p> Signup and view all the answers

Which gastrointestinal symptom is suggestive of cholestasis related to biliary obstruction?

<p>Epigastric tenderness (A)</p> Signup and view all the answers

What adaptation occurs in the intestines due to biliary obstruction?

<p>Decreased reabsorption of bile acids (A)</p> Signup and view all the answers

In cholestasis, what may indicate evidence of gross fat malabsorption?

<p>Stool changes suggesting fat malabsorption (D)</p> Signup and view all the answers

Which clinical condition may lead to cholestasis?

<p>Chronic viral hepatitis (C)</p> Signup and view all the answers

What symptom may be suggestive of primary biliary cholangitis?

<p>Right upper quadrant pain or tenderness (A)</p> Signup and view all the answers

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