Toxicology: Effects of Substance Abuse
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Questions and Answers

After a certain amount of units, which organs are damaged?

  • Liver, myocardium, and nervous system
  • Liver and myocardium
  • Liver, heart, and skeletal muscles
  • Liver, myocardium, and endocrine glands (correct)
  • At what point do organ damages occur in adults?

  • After 20 units
  • After 70 units
  • After 30 units
  • After 50 units (correct)
  • What is true about the amount of units in children compared to adults?

  • Children have the same amount of units
  • Children have no units
  • Children have a higher amount of units
  • Children have a lesser amount of units (correct)
  • What type of glands are damaged?

    <p>Endocrine glands</p> Signup and view all the answers

    What is the order of organ damage?

    <p>Liver, myocardium, endocrine glands</p> Signup and view all the answers

    What is the platelet count threshold for considering platelet transfusion?

    <p>100,000 /µL</p> Signup and view all the answers

    Why might platelet transfusion be necessary?

    <p>To prevent bleeding</p> Signup and view all the answers

    In which situation might platelet transfusion be required?

    <p>Before surgical intervention</p> Signup and view all the answers

    What is a potential consequence of a low platelet count?

    <p>Increased risk of bleeding</p> Signup and view all the answers

    When might platelet transfusion be considered?

    <p>If there is bleeding or surgical intervention</p> Signup and view all the answers

    What is the primary goal of aggressive early replacement in massive blood transfusion?

    <p>To maintain normal tissue perfusion</p> Signup and view all the answers

    What is the consequence of too little blood transfusion too late?

    <p>Far more serious consequences than massive blood transfusion itself</p> Signup and view all the answers

    Why is aggressive early replacement essential in massive blood transfusion?

    <p>To maintain normal tissue perfusion and prevent development of coagulopathy or thrombocytopenia</p> Signup and view all the answers

    What is the result of inadequate blood transfusion?

    <p>Far more serious consequences than massive blood transfusion itself</p> Signup and view all the answers

    What is the main consideration in massive blood transfusion?

    <p>To replace blood loss quickly and adequately</p> Signup and view all the answers

    What is the percentage of bacterial contamination in Packed RBC units according to a local study?

    <p>9%</p> Signup and view all the answers

    What is commonly found in the soil?

    <p>Bacterial contamination</p> Signup and view all the answers

    What is Bacillus subtilis considered to be?

    <p>Not pathogenic or toxic to humans</p> Signup and view all the answers

    What type of study is mentioned in the content?

    <p>Local study</p> Signup and view all the answers

    What is packed in Packed RBC units?

    <p>Red blood cells</p> Signup and view all the answers

    What is one of the causes of post transfusion hepatitis?

    <p>Hepatitis viruses (A, B, C)</p> Signup and view all the answers

    Which of the following viruses is not a cause of post transfusion hepatitis?

    <p>Rabies virus</p> Signup and view all the answers

    What is a common cause of post transfusion hepatitis, besides hepatitis viruses?

    <p>Cytomegalovirus (CMV)</p> Signup and view all the answers

    Which of the following is a cause of post transfusion hepatitis?

    <p>Epstein-Bar virus (EBV)</p> Signup and view all the answers

    What is a cause of post transfusion hepatitis, which is not a type of hepatitis virus?

    <p>Cytomegalovirus (CMV)</p> Signup and view all the answers

    Study Notes

    Blood Transfusion and Complications

    • After 50 units in adults, and a lesser amount in children, the liver, myocardium, and endocrine glands are damaged.

    Platelet Transfusion

    • Platelet transfusion is given when platelet count falls below 100,000/µL, especially in cases of bleeding or surgical intervention.

    Bacterial Contamination in Packed RBC Units

    • Bacterial contamination in packed RBC units is a common issue, with a local study showing a 9% contamination rate.
    • Bacillus subtilis, a contaminant, is not pathogenic or toxigenic to humans.

    Massive Blood Transfusion

    • The most important consideration in massive blood transfusion is to replace blood loss quickly and adequately to maintain normal tissue perfusion and prevent coagulopathy or thrombocytopenia.

    Complications of Blood Transfusion

    • Delayed or inadequate blood transfusion can have more severe consequences than the transfusion itself.
    • Post-transfusion hepatitis can be caused by:
      • Hepatitis viruses (A, B, C)
      • Cytomegalovirus (CMV)
      • Epstein-Barr virus (EBV)

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    Description

    This quiz assesses your understanding of the effects of substance abuse on the human body. Specifically, it explores the damage caused to the liver, myocardium, and endocrine glands after a certain amount of units in adults and children.

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