Total Body Water and Fluid Compartments
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Questions and Answers

What percentage of total body water is typically found in adults?

  • 40-45%
  • 60% in males, 50-55% in females (correct)
  • Up to 85%
  • 70-75%

At what age is total body water approximately 70-75%?

  • Extreme age
  • Adulthood
  • At birth
  • At 1 year of age (correct)

At what age is total body water up to 85%?

  • At birth (correct)
  • Extreme age
  • Adulthood
  • At 1 year of age

What fraction of total body water does extracellular fluid represent?

<p>1/3 TBW (A)</p> Signup and view all the answers

In children 6 months of age and older, interstitial fluid represents what fraction of extracellular fluid?

<p>3/4 ECF (A)</p> Signup and view all the answers

In children 6 months of age and older, what fraction of extracellular fluid does plasma represent?

<p>1/4 ECF (B)</p> Signup and view all the answers

What is the gram-molecular weight of Sodium?

<p>23.0</p> Signup and view all the answers

What is the intravascular concentration of Sodium (in mEq/L)?

<p>145</p> Signup and view all the answers

What is the intracellular concentration of Potassium (in mEq/L)?

<p>140</p> Signup and view all the answers

What is the interstitial concentration of Chloride (in Meq/L)?

<p>110</p> Signup and view all the answers

Which age group has the highest percentage of total body water (TBW)?

<p>Neonate (B)</p> Signup and view all the answers

Which of the following correctly lists the body fluid compartments?

<p>Extracellular and Intracellular (C)</p> Signup and view all the answers

The percentage of blood volume is higher in neonates than young adults.

<p>True (A)</p> Signup and view all the answers

In pregnancy, blood and plasma volumes increase by 45% and 50% respectively by term.

<p>True (A)</p> Signup and view all the answers

Flashcards

Total Body Water (TBW)

The total volume of water in the body, expressed as a percentage of body weight.

TBW at Birth

Up to 85% (70-80%) of body weight in newborns.

TBW at 1 Year

70-75% of body weight by one year of age.

TBW in Adults

Approximately 60% in males and 50-55% in females.

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TBW in Elderly

Total body water decreases to 40-45% in elderly individuals.

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Extracellular Fluid (ECF)

Fluid outside of cells, comprising about 1/3 of TBW.

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Interstitial Fluid

Fluid found between cells, making up 3/4 of ECF.

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Intravascular Fluid

Fluid contained within blood vessels, accounting for 1/4 of ECF.

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Intracellular Fluid

Fluid contained within cells, comprising about 2/3 of TBW.

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Sodium in ECF

Main cation in extracellular fluid, with a concentration of 145 mEq/L.

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Potassium in ICF

Major cation in intracellular fluid, with a concentration of 140 mEq/L.

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Calcium in Body Fluids

Important for various physiological functions, detailed values are provided.

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Fluid Composition of TBW

TBW is divided into ECF (1/3) and ICF (2/3).

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ECF Composition

ECF consists of interstitial fluid (3/4) and intravascular fluid (1/4).

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Age-Related Variation

TBW decreases from birth to old age.

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Pregnancy Blood Volume

During pregnancy, blood and plasma volumes increase by 45% and 50%, respectively.

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Blood Volume in Neonates

Blood volume in neonates is about 9% of body weight.

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6-month Blood Volume

Blood volume decreases further as babies grow, specific values not provided.

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Fluid Compartments Diagram

Visual representation showing the hierarchical structure of body fluid compartments.

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Fluid Volume Ratios

Understanding the ratios helps in medical assessments.

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Fluid Balance Importance

Maintaining fluid balance is essential for physiological functions.

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Age Effects on Body Water

Younger individuals have higher TBW percentages compared to older adults.

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ECF vs. ICF Comparison

ECF is outside cells; ICF is inside cells.

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Fluid Distribution

Distribution of fluids impacts physiological processes.

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Main Electrolytes in Body Fluids

Sodium and potassium are key electrolytes in ECF and ICF.

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Study Notes

Total Body Water

  • At birth, total body water is up to 85% (70-80%) of body weight.
  • At 1 year of age, total body water is 70-75%
  • Adult male total body water is about 60%
  • Adult female total body water is 50-55%
  • Extreme age (elderly) total body water is 40-45%

Body Fluid Compartments

  • Total body water (TBW) is divided into extracellular fluid (ECF) and intracellular fluid.
  • ECF is further divided into interstitial fluid (ISF) and intravascular fluid.
  • ISF (3/4 ECF) accounts for 3/4 of the total extracellular fluid.
  • Intravascular fluid(1/4 ECF)accounts for 1/4 of the total extracellular fluid.

Composition of Fluid Compartments

  • Table 49-2 details the composition of different fluid compartments (intracellular and extracellular) in miliequivalents per liter (mEq/L).
  • Sodium levels in extracellular fluid are approximately 145 mEq/L and 10 mEq/L in intracellular fluid.
  • Potassium levels are 4 mEq/L in extracellular fluid and 140 mEq/L in intracellular fluid
  • Calcium levels in extracellular fluid are approximately 3 mEq/L with less than 1 mEq/L in intracellular fluid.
  • Chloride levels in extracellular fluid are about 105 mEq/L and 4 mEq/L in intracellular fluid.
  • Bicarbonate levels are 24 mEq/L in extracellular fluid and 10 mEq/L in intracellular fluid
  • Phosphorus levels are approximately 75 mEq/L in intracellular fluid and 2mEq/L in extracellular fluids
  • Protein level variations between compartments exist

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Description

This quiz explores the various aspects of total body water, including its percentage at different life stages and the composition of body fluid compartments. Additionally, it delves into the distinctions between extracellular and intracellular fluids and their electrolyte compositions. Test your knowledge on these vital concepts related to human physiology.

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