Total Body Water and Fluid Compartments

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Questions and Answers

What percentage of total body water (TBW) is typically found in a neonate?

  • 40-45%
  • 60-65%
  • 50%
  • 70-80% (correct)

What is the approximate ratio of extracellular fluid (ECF) to total body water (TBW)?

  • 1/2 TBW
  • 3/4 TBW
  • 2/3 TBW
  • 1/3 TBW (correct)

Which of the following best describes the distribution of extracellular fluid (ECF) in the body?

  • 1/4 intravascular, 3/4 interstitial (correct)
  • 3/4 intravascular, 1/4 interstitial
  • 1/2 intravascular, 1/2 interstitial
  • 1/3 intravascular, 2/3 interstitial

What is the approximate blood volume percentage in a young adult?

<p>7% (B)</p> Signup and view all the answers

In adults, what is the approximate total body water (TBW) percentage in females?

<p>50-55% (C)</p> Signup and view all the answers

What is the approximate intracellular concentration of Sodium (Na+)?

<p>10 mEq/L (B)</p> Signup and view all the answers

What is the approximate intracellular concentration of Potassium (K+)?

<p>140 mEq/L (B)</p> Signup and view all the answers

Under normal conditions, which age group would you expect to have the lowest percentage of total body water (TBW)?

<p>Elderly individual (C)</p> Signup and view all the answers

Flashcards

Total Body Water (TBW)

The total amount of water in a person's body, expressed as a percentage of body weight.

ECF (Extracellular Fluid)

Fluid outside of cells, making up about 1/3 of Total Body Water.

ICF (Intracellular Fluid)

Fluid within cells, making up about 2/3 of Total Body Water.

Neonate TBW percentage

Total Body Water percentage in neonates is approximately 80% of body weight.

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Elderly TBW percentage

Total Body Water percentage in elderly individuals is about 50-55% of body weight.

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Sodium in ECF vs ICF

Sodium concentration is higher in the extracellular fluid (145 mEq/L) than in intracellular fluid (10 mEq/L).

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Potassium in ICF vs ECF

Potassium concentration is significantly higher in intracellular fluid (140 mEq/L) than in extracellular fluid (4 mEq/L).

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Age-related TBW change

Total Body Water decreases with age; it is highest at birth and lowest in elderly.

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Study Notes

Total Body Water

  • At birth, total body water accounts for 70-80% of body weight.
  • At one year of age, it is about 70-75%
  • In adults, males have 60% and females have 50-55% of their weight as total body water.
  • In extreme old age, it is about 40-45%.
  • Pregnancy increases blood and plasma volume by 45% and 50%, respectively.

Body Fluid Compartments

  • Total body water is divided into extracellular fluid and intracellular fluid.
  • Extracellular fluid (ECF) is one-third of total body water (TBW).
  • ECF is further divided into interstitial fluid (comprising 3/4 of ECF) and intravascular fluid (comprising 1/4 of ECF).
  • Intracellular fluid is the remaining two-thirds of TBW.
  • These proportions are different at various ages

Composition of Fluid Compartments

  • The table lists the composition of different fluid compartments (intracellular, interstitial, intravascular)
  • It shows the concentration of various electrolytes (e.g., sodium, potassium, calcium, chloride, bicarbonate, phosphorus) in milliequivalents per liter (mEq/L) and protein in grams per deciliter (g/dL)
  • Values are accurate for children 6 months of age and older

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